Starting at $247
Starting at $363
Starting at $389
Starting at $429
Starting at $577
Helping travelers to find the best flight offers
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santo Domingo to Madrid. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A direct flight is the most convenient and comfortable way to fly from Santo Domingo to Madrid, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santo Domingo to Madrid:
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We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
More than 5 airlines operate flights from Santo Domingo to Madrid, including Welcome Air, Air Europa, Iberia, Asian Air, and Frontier Airlines. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $247, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
Starting at $247
Starting at $363
Starting at $389
Starting at $429
Starting at $577
Santo Domingo — Madrid
12/14/2025
Departure
Direct flight
2W3410
Starting at $247
Santo Domingo — Madrid
12/12/2025
Departure
Direct flight
2W3410
Starting at $256
Santo Domingo — Madrid
12/25/2025
Departure
Direct flight
UX088
Starting at $363
Santo Domingo — Madrid
12/23/2025
Departure
Direct flight
UX186
Starting at $365
Santo Domingo — Madrid
12/22/2025
Departure
Direct flight
UX186
Starting at $377
Santo Domingo — Madrid
12/16/2025
Departure
Direct flight
IB264
Starting at $389
Santo Domingo — Madrid
12/17/2025
Departure
Direct flight
IB266
Starting at $390
Santo Domingo — Madrid
12/18/2025
Departure
Direct flight
IB266
Starting at $390
Santo Domingo — Madrid
12/11/2025
Departure
Direct flight
UX88
Starting at $449
Santo Domingo — Madrid
12/10/2025
Departure
Direct flight
UX88
Starting at $452
Unable to find information about the schedule of direct flights from
The cheapest flight ticket from Santo Domingo to Madrid according to data for the last 48 hours costs $247
Often the best time to buy tickets from Santo Domingo to Madrid is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santo Domingo to Madrid can be found flying in these months: December, January.
The fastest flights from Santo Domingo to Madrid start from 8 hours 5 minutes in the air.
The following airlines operate direct flights on the route Santo Domingo — Madrid: Welcome Air, Air Europa, Iberia
The cost of a one-way flight from Santo Domingo to Madrid ranges from $344 (December 2025) to $485 (January 2026). On average, the ticket price is about $415–$485.
The cheapest one-way flight from Santo Domingo to Madrid departs on 12/14/2025, is operated by Welcome Air and costs $247
The cheapest roundtrip flight from Santo Domingo to Madrid departs on 05/15/2026, is operated by Welcome Air and costs $790
Fastest flight from Santo Domingo to Madrid takes 8h 5m
There are direct flights on this route 6 days a week: Su, Mo, Tu, We, Th, and Fr
The distance between Santo Domingo and Madrid is 6699km (4153 miles). There are 19 direct flights from Santo Domingo to Madrid. The time difference between Santo Domingo and Madrid is 5h. Flights from Santo Domingo begin at 4:30 PM. The latest flight from Santo Domingo departs at 11:05 PM
We couldn't find any special offers for flights from Santo Domingo to Madrid