Airlines operating on route
Starting at $409
Starting at $443
Starting at $446
Starting at $453
Starting at $494
Starting at $559
Starting at $603
Starting at $614
Starting at $628
Starting at $727
Starting at $798
Helping travelers to find the best flight offers
Starting at $409
Starting at $443
Starting at $446
Starting at $453
Starting at $494
Starting at $559
Starting at $603
Starting at $614
Starting at $628
Starting at $727
Starting at $798
Madrid — Santiago
03/17/2025
Departure date
Direct flight
IB113
Starting at $813
Madrid — Santiago
03/21/2025
Departure date
Direct flight
LA6586
Starting at $785
Madrid — Santiago
03/24/2025
Departure date
Direct flight
IB117
Starting at $750
Madrid — Santiago
03/25/2025
Departure date
Direct flight
LA705
Starting at $784
Madrid — Santiago
03/28/2025
Departure date
Direct flight
IB113
Starting at $785
Madrid — Santiago
03/29/2025
Departure date
Direct flight
LA705
Starting at $1,172
Madrid — Santiago
03/30/2025
Departure date
Direct flight
LA707
Starting at $785
Madrid — Santiago
03/31/2025
Departure date
Direct flight
IB117
Starting at $714
Madrid — Santiago
04/05/2025
Departure date
Direct flight
LA705
Starting at $989
Madrid — Santiago
04/07/2025
Departure date
Direct flight
IB117
Starting at $708
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Madrid to Santiago:
Iberia
Su, Mo, Tu, We, Th, and Fr
Starting at $739
LATAM Chile
Every day
Starting at $779
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Madrid to Santiago. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
The cheapest flight ticket from Madrid to Santiago according to data for the last 48 hours costs $409
Often the best time to buy tickets from Madrid to Santiago is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Madrid to Santiago can be found flying in these months: April, March, June.
The fastest flights from Madrid to Santiago start from 17 hours 15 minutes in the air.
The following airlines operate direct flights on the route Madrid — Santiago: Iberia, LATAM Chile
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Madrid to Santiago
Below you will find a list of airlines operating flights on the Madrid — Santiago route and the starting prices for flights of each specific airline on it.
A direct flight is the most convenient and comfortable way to fly from Madrid to Santiago, despite the fact that sometimes flights with transfers can cost significantly less.
The cheapest one-way flight from Madrid to Santiago departs on 03/28/2025, is operated by Iberia and costs $409
The cheapest roundtrip flight from Madrid to Santiago departs on 12/10/2025, is operated by British Airways and costs $913
Fastest flight from Madrid to Santiago takes 17h 15m
There are no direct flights on this route.
The distance between Madrid and Santiago is 10691km (6628 miles). The average flight duration is 13h 21m. There are 31 direct flights from Madrid to Santiago. The time difference between Madrid and Santiago is 5h . Flights from Madrid begin at 11:05 AM. The latest flight from Madrid departs at 11:59 PM.
We couldn't find any special offers for flights from Madrid to Santiago
