LATAM Chile
Mo, Tu, We, Th, Fr, and Sa
starting at $734
Iberia
Tu, Th, and Fr
starting at $549
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Madrid to Santiago. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Madrid to Santiago, despite the fact that sometimes flights with transfers can cost significantly less.
The airlines on the Madrid — Santiago route each fly on specific days: LATAM Chile flies every day except Sunday. Iberia only flies on Tuesday, Thursday, and Friday.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
LATAM Chile
Mo, Tu, We, Th, Fr, and Sa
starting at $734
Iberia
Tu, Th, and Fr
starting at $549
The minimum one-way ticket price from Madrid to Santiago is $475 (May 2026), while the maximum is $966 (August 2026). On average, a ticket costs $594–$662.
Prices on the Madrid — Santiago route are unpredictable: costs change from month to month with no clear pattern. Still, even here some periods are more affordable than others.
Despite the fluctuations, patterns exist: the cheapest period is May 2026–June 2026 — averaging $515. The most expensive is July 2026–August 2026 ($902). The difference reaches 43%.
With this kind of price behavior, it's worth comparing prices across several months and booking when a good deal appears. A good benchmark is May 2026–June 2026, where you can save up to 43%.
Price spread on this route is 22.4%. Costs vary significantly, so your choice of month can noticeably affect your travel budget.
Madrid — Santiago
05/16/2026
Departure
Direct flight
LA707
starting at $784
Madrid — Santiago
05/17/2026
Departure
Direct flight
LA707
starting at $694
Madrid — Santiago
05/24/2026
Departure
Direct flight
LA6651
starting at $745
Madrid — Santiago
05/27/2026
Departure
Direct flight
IB113
starting at $619
Madrid — Santiago
05/29/2026
Departure
Direct flight
IB113
starting at $610
Madrid — Santiago
05/31/2026
Departure
Direct flight
LA1790
starting at $953
Madrid — Santiago
06/01/2026
Departure
Direct flight
IB113
starting at $898
Madrid — Santiago
08/13/2026
Departure
Direct flight
IB117
starting at $841
Madrid — Santiago
09/28/2026
Departure
Direct flight
LA707
starting at $875
Madrid — Santiago
11/05/2026
Departure
Direct flight
LA707
starting at $778
starting at $431
starting at $542
starting at $562
starting at $568
starting at $580
starting at $618
starting at $645
starting at $669
starting at $813
starting at $858
starting at $871
starting at $875
The Madrid — Santiago route is served by a wide range of airlines: 12 in total, including LATAM Chile, Iberia, Air Ocean, United Airlines, Avianca, Air Canada, Ryanair, LC Busre SAC, Aerolineas Argentinas, Azul Brazilian Airlines, Aeromexico, and DHL Aviation EEMEA B.S.C.(c). Competition among carriers gives passengers the opportunity to find tickets at attractive fares — with prices starting from $431. Our service helps compare all available offers within seconds and choose the most convenient option. You can filter flights by price, departure time, or baggage rules to make your trip as comfortable as possible. With so many airlines, there’s always a chance to catch special promotions and save.
The cheapest flight ticket from Madrid to Santiago according to data for the last 48 hours costs $431
Often the best time to buy tickets from Madrid to Santiago is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Madrid to Santiago can be found flying in these months: May, June, September.
The fastest flights from Madrid to Santiago start from 13 hours 20 minutes in the air.
The following airlines operate direct flights on the route Madrid — Santiago: LATAM Chile, Iberia
We couldn't find any special offers for flights from Madrid to Santiago
The cheapest one-way flight from Madrid to Santiago departs on 06/09/2026, is operated by LATAM Chile and costs $431
The cheapest roundtrip flight from Madrid to Santiago departs on 06/01/2026, is operated by LATAM Chile and costs $938
Fastest flight from Madrid to Santiago takes 13h 20m
There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa
The distance between Madrid and Santiago is 10691km (6628 miles). The average flight duration is 13h 20m. There are 28 direct flights from Madrid to Santiago. The time difference between Madrid and Santiago is 5h. Flights from Madrid begin at 1:00 PM. The latest flight from Madrid departs at 11:59 PM
