Cheap Flights from Madrid to Santiago

Cheapest flights from Madrid to Santiago

Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Madrid to Santiago. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.

Cheapest one way flight

$490

Avianca

1 layover

18h 55m

02/27/2027

The cheapest one-way flight from Madrid to Santiago departs on 02/27/2027, is operated by Avianca and costs $490

Cheapest round trip flight

$854

Azul Brazilian Airlines

1 layover

1d 23h 10m

11/28/2026

The cheapest roundtrip flight from Madrid to Santiago departs on 11/28/2026, is operated by Azul Brazilian Airlines and costs $854

The fastest flight

13h 20m

Fastest flight from Madrid to Santiago takes 13h 20m

Direct flights

Every day

There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa

Earliest flight

1:00 PM

Latest flight

11:59 PM

Average flight duration

13h 30m

Direct flights count

29

Distance

10701km

Timezone difference

5h

The distance between Madrid and Santiago is 10701km (6635 miles). The average flight duration is 13h 30m. There are 29 direct flights from Madrid to Santiago. The time difference between Madrid and Santiago is 5h. Flights from Madrid begin at 1:00 PM. The latest flight from Madrid departs at 11:59 PM

Remember that on average the ideal time to book flights is 2 months before departure!

Airfare from Madrid to Santiago by month

The minimum one-way ticket price from Madrid to Santiago is $508 (March 2027), while the maximum is $693 (January 2027). On average, a ticket costs $622–$1,357.

March 2027

Lowest price

on average:

$508

January 2027

Highest price

on average:

$693

Avg Price

Price dynamics

On the Madrid — Santiago route, prices first decline, hit a low, then start rising again. The middle of the period creates a price window — the best time to book.

Cheaper and more expensive periods

Prices fall from October 2026 to November 2026 (20%), then rise from November 2026 to January 2027 (+25%). The best period is January 2027–March 2027 ($600), the most expensive is December 2026–January 2027 ($681).

Best time to buy

The best time to buy is January 2027–March 2027, when prices are at their lowest. This can save you up to 12% compared to the expensive months (December 2026–January 2027).

Price predictability

Monthly price variation is 12.4%. On this route, your departure date noticeably affects the cost, and choosing wisely can lead to real savings.

Airlines operating on route

The Madrid — Santiago route is served by a wide range of airlines: 11 in total, including Iberia, LATAM Chile, Avianca, United Airlines, Azul Brazilian Airlines, Air Europa, TAP Portugal, Ryanair, Aerolineas Argentinas, LASER Airlines, and EuroAtlantic Airways S.A.. Competition among carriers gives passengers the opportunity to find tickets at attractive fares — with prices starting from $490. Our service helps compare all available offers within seconds and choose the most convenient option. You can filter flights by price, departure time, or baggage rules to make your trip as comfortable as possible. With so many airlines, there’s always a chance to catch special promotions and save.

starting at $504

starting at $705

starting at $490

starting at $571

Azul Brazilian Airlines

starting at $591

Air Europa

starting at $592

TAP Portugal

starting at $594

Ryanair

starting at $694

Aerolineas Argentinas

starting at $731

LASER Airlines

starting at $911

EuroAtlantic Airways S.A.

starting at $966

Non-stop flights from Madrid to Santiago

A non-stop flight is the most convenient and comfortable way to fly from Madrid to Santiago, despite the fact that sometimes flights with transfers can cost significantly less.

Madrid — Santiago

MAD — SCL

12/30/2026

Departure

Direct flight

IB117

starting at $743

Madrid — Santiago

MAD — SCL

02/26/2027

Departure

Direct flight

IB113

starting at $508

Madrid — Santiago

MAD — SCL

02/27/2027

Departure

Direct flight

IB117

starting at $806

Madrid — Santiago

MAD — SCL

11/12/2026

Departure

Direct flight

IB113

starting at $849

Madrid — Santiago

MAD — SCL

03/26/2027

Departure

Direct flight

IB113

starting at $504

Madrid — Santiago

MAD — SCL

02/11/2027

Departure

Direct flight

IB117

starting at $529

Madrid — Santiago

MAD — SCL

02/13/2027

Departure

Direct flight

IB117

starting at $578

Madrid — Santiago

MAD — SCL

02/12/2027

Departure

Direct flight

IB113

starting at $580

Madrid — Santiago

MAD — SCL

01/02/2027

Departure

Direct flight

IB113

starting at $745

Madrid — Santiago

MAD — SCL

01/07/2027

Departure

Direct flight

IB113

starting at $752

Schedule of direct flights from Madrid to Santiago

There are most likely no direct flights on the Madrid — Santiago route

Madrid airports overview

Adolfo Suarez Madrid-Barajas Airport

•

MAD

13km

Madrid's main international airport handles domestic, European and long‑haul flights, with multiple terminals and frequent connections across Spain, Europe and Latin America.

•

Santiago airports overview

Arturo Merino Benitez Airport

•

SCL

23km

Santiago’s main international gateway serving Chile’s capital, offering domestic and international routes and connections across the country. Accessible to downtown by bus, taxi and highway links.

•

Frequently asked questions (FAQ)

Answers to questions about the route that travelers are most interested in.

What is the cheapest price for flights from Madrid to Santiago?

The cheapest flight ticket from Madrid to Santiago according to data for the last 48 hours costs $490

When is the best time to buy air tickets on the route Madrid — Santiago?

Often the best time to buy tickets from Madrid to Santiago is 2 months before departure.

When is the cheapest time of year to fly from Madrid to Santiago?

Based on statistics over the past years, the lowest prices for flights from Madrid to Santiago can be found flying in these months: March, November, December.

How long does it take to fly from Madrid to Santiago?

The fastest flights from Madrid to Santiago start from 13 hours 20 minutes in the air.

Which airline can fly direct from Madrid to Santiago?

The following airlines operate direct flights on the route Madrid — Santiago: Iberia, LATAM Chile

Special offers and sales on air tickets from Madrid to Santiago

We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.

Madrid — Santiago

février 27

Avianca

$539

Alternative routes

Albacete ➜ Santiago•Burgos ➜ Santiago•Logrono ➜ Santiago•Valladolid ➜ Santiago•Zaragoza ➜ Santiago•Madrid ➜ San Rafael•Madrid ➜ Concepcion•Madrid ➜ La Rioja•Madrid ➜ Vina del Mar•Madrid ➜ La Serena•Madrid ➜ Mendoza•Madrid ➜ Rio Cuarto•Madrid ➜ Merlo•Madrid ➜ San Juan•Madrid ➜ Temuco

•••••••••••••••••••

Cheapest one way flight

$490

Avianca

1 layover

18h 55m

02/27/2027

The cheapest one-way flight from Madrid to Santiago departs on 02/27/2027, is operated by Avianca and costs $490

Cheapest round trip flight

$854

Azul Brazilian Airlines

1 layover

1d 23h 10m

11/28/2026

The cheapest roundtrip flight from Madrid to Santiago departs on 11/28/2026, is operated by Azul Brazilian Airlines and costs $854

The fastest flight