Copa Airlines
Every day
starting at $253
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Sao Paulo to Panama City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
The cost of a one-way flight from Sao Paulo to Panama City ranges from $265 (November 2026) to $441 (January 2027). On average, the ticket price is about $352–$703.
A non-stop flight is the most convenient and comfortable way to fly from Sao Paulo to Panama City, despite the fact that sometimes flights with transfers can cost significantly less.
The only airline operating direct flights from Sao Paulo to Panama City is Copa Airlines. Flights operate every day.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The Sao Paulo — Panama City route shows a classic seasonal pattern: prices rise, peak, then fall again. Knowing this, you can pick a more affordable time to fly.
Prices rise from October 2026 to January 2027 (+66%), then decline from January 2027 to August 2027 (21%). The cheapest tickets are in October 2026–November 2026 (averaging $265), while the priciest are in December 2026–January 2027 ($440).
For savings, plan your flight for October 2026–November 2026 — you could save up to 40%. Try to avoid December 2026–January 2027 when possible: prices are at their highest then.
Price spread on this route is 18.8%. Costs depend heavily on the season, so flexibility in choosing your departure month is especially valuable here.
Copa Airlines
Every day
starting at $253
All airports
Sao Paulo — Panama City
11/04/2026
Departure
Direct flight
CM758
starting at $351
Sao Paulo — Panama City
02/15/2027
Departure
Direct flight
CM700
starting at $714
Sao Paulo — Panama City
01/11/2027
Departure
Direct flight
CM841
starting at $814
Sao Paulo — Panama City
11/27/2026
Departure
Direct flight
CM758
starting at $865
Sao Paulo — Panama City
01/03/2027
Departure
Direct flight
CM758
starting at $902
Sao Paulo — Panama City
02/10/2027
Departure
Direct flight
CM758
starting at $964
Sao Paulo — Panama City
11/03/2026
Departure
Direct flight
CM758
starting at $808
Sao Paulo — Panama City
11/13/2026
Departure
Direct flight
CM758
starting at $916
Sao Paulo — Panama City
11/21/2026
Departure
Direct flight
CM841
starting at $622
Sao Paulo — Panama City
11/20/2026
Departure
Direct flight
CM700
starting at $799
starting at $246
starting at $322
starting at $502
starting at $608
starting at $659
More than 5 airlines operate flights from Sao Paulo to Panama City, including Copa Airlines, Avianca, Sky Airline, LATAM Chile, and LATAM Brasil. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $246, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
The cheapest flight ticket from Sao Paulo to Panama City according to data for the last 48 hours costs $246
Often the best time to buy tickets from Sao Paulo to Panama City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Sao Paulo to Panama City can be found flying in these months: November, October, August.
The fastest flights from Sao Paulo to Panama City start from 6 hours 59 minutes in the air.
The following airlines operate direct flights on the route Sao Paulo — Panama City: Copa Airlines
The cheapest one-way flight from Sao Paulo to Panama City departs on 11/03/2026, is operated by Copa Airlines and costs $246
The cheapest roundtrip flight from Sao Paulo to Panama City departs on 11/13/2026, is operated by Copa Airlines and costs $537
Fastest flight from Sao Paulo to Panama City takes 6h 59m
There are direct flights on this route 6 days a week: Su, Mo, Tu, We, Fr, and Sa
The distance between Sao Paulo and Panama City is 5086km (3153 miles). The average flight duration is 6h 58m. There are 92 direct flights from Sao Paulo to Panama City. The time difference between Sao Paulo and Panama City is 2h. Flights from Sao Paulo begin at 4:45 AM. The latest flight from Sao Paulo departs at 3:15 AM
We couldn't find any special offers for flights from Sao Paulo to Panama City
