Cheap Flights from Sao Paulo to Panama City — $226

Flights from Sao Paulo to Panama City are operated by several airlines — Azul Brazilian Airlines, Copa Airlines, and Avianca. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $226, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.

São Paulo–Guarulhos International (GRU) is the city’s main international hub and typically handles most long-haul and premium carriers, including flag and full-service airlines. Located about 25–30 km northeast of downtown São Paulo, travel times to the center are generally 40–60 minutes by airport taxi or app-based car services, and 45–75 minutes by airport bus or shuttle depending on traffic; fares can range from moderate to premium. A rail link (Airport Express and commuter connections) is becoming more available and can be a cost-competitive option. Pros: extensive international connections and full-service facilities; cons: can be busy and subject to heavy traffic on road links, which may affect transfers. Congonhas Airport (CGH) functions primarily as São Paulo’s domestic and regional airport and is usually favored by business travelers for short-haul flights operated by legacy and regional airlines. It sits conveniently close to the city center — roughly 8–11 km — so transfers are often quick: expect about 20–40 minutes by taxi or rideshare, and similar times by bus depending on traffic; fares are typically lower than long-distance transfers but can vary with peak-hour demand. Pros: excellent proximity and frequent domestic schedules; cons: limited international services and potentially cramped peak-hour terminal areas. Viracopos–Campinas (VCP) serves as a secondary international and cargo-oriented airport and is commonly used for low-cost carriers and freight operations. It is located about 95–110 km northwest of central São Paulo, so journey times can be around 1–1.5 hours by car or intercity bus, with buses often offering economical fares but longer door-to-door times. Pros: often less congested and can have more budget-friendly fares for certain routes; cons: substantial distance from São Paulo’s core makes transfers lengthier and less convenient for tight connections. São Paulo–Campo de Marte (private/heliport operations) is primarily a smaller, general aviation and helicopter hub close to the city, used for private flights, air taxis and some charter services. It lies within the northern part of the metropolis and is typically just a short drive to central neighborhoods, making it convenient for specialized travel needs; road times are usually under 30 minutes when traffic permits. Pros: very convenient for private and rapid transfers; cons: not suitable for scheduled commercial flights and lacking full passenger terminals and services.

Direct flights

The distance between Sao Paulo and Panama City is 5089km (3155 miles). There are 85 direct flights from Sao Paulo to Panama City. The time difference between Sao Paulo and Panama City is 2h. Flights from Sao Paulo begin at 5:25 AM. The latest flight from Sao Paulo departs at 3:10 AM

Panama City is primarily served by Tocumen International Airport (PTY), the country’s main international hub and a key connecting point for Latin America. PTY typically hosts full-service carriers and regional airlines, so fares can range from budget-friendly to premium depending on carrier and routing. The airport sits about 24 km (15 miles) east of downtown Panama City; travel by taxi or rideshare usually takes 25–40 minutes and can be moderately priced, while the MetroBus and occasional airport shuttle are cheaper but slower options. Tocumen offers extensive passenger facilities and international connections, though peak times can mean longer lines and transfers may require extra time. For some low-cost or domestic flights, smaller airports and regional terminals closer to the city can be used, offering shorter commutes but fewer long-haul options.

The cost of a one-way flight from Sao Paulo to Panama City ranges from $227 (February 2026) to $238 (May 2026). On average, the ticket price is about $234–$470.