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Find the best flights from São Paulo to Medellín with our fast search across 700+ airlines, 50+ agencies and 5+ top booking systems to uncover the cheapest fares, ideal schedules and flexible conditions. Compare options in seconds and book confidently for a smooth trip to Colombia’s vibrant city.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Sao Paulo to Medellin:
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Answers to questions about the route that travelers are most interested in.
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The Sao Paulo — Medellin route is served by multiple airlines, including Asian Air, Copa Airlines, and LATAM Chile. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $143, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.
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São Paulo is served by two main airports with distinct roles. São Paulo/Guarulhos–Governador André Franco Montoro (GRU) is the primary international hub, typically handling most long-haul and full-service carriers as well as some regional airlines; it is generally perceived as mid-to-upper range on price for transfers and services. GRU lies about 25–30 km northeast of downtown São Paulo, with airport buses, app taxis and ride-shares taking roughly 40–60 minutes depending on traffic (fares vary by operator), and an airport rail link offering faster connections in some services. Pros: broad airline choice and comprehensive facilities; cons: can be busy and transfers may be lengthy. Congonhas–Sao Paulo (CGH) functions primarily as a domestic/business airport favored by legacy carriers and short-haul flights, typically seen as more budget-friendly for quick regional hops. It sits much closer to the city center (around 8–10 km), with taxis and ride-shares usually taking 20–35 minutes, and local buses or shuttle options commonly available for lower fares. Pros: convenient for downtown access and short check-in times; cons: limited international services and stricter noise-driven operating hours.
Fly nonstop from São Paulo to Medellín for the quickest, most convenient way to reach Colombia’s vibrant city—less travel time, no layovers, and a smoother door-to-door experience. While connecting options can sometimes be cheaper, choosing a direct flight saves hours and reduces hassle, making it ideal for business trips or maximizing your time exploring Medellín.
José María Córdova International Airport (MDE) serves as Medellín’s main international gateway and typically functions as the city’s full-service hub for long-haul and regional flights. Major carriers and several international airlines usually operate here, so fares can be mid-to-high compared with smaller local fields. The airport is located roughly 35–45 minutes from Medellín’s city center by car (about 35–50 km depending on traffic); transfers are commonly by taxi or shared shuttle (roughly COP 70,000–120,000 typical taxi fares) or private transfer services. Pros: more flight options and international connections; cons: longer transfer time and occasionally heavy traffic to town. It can be a good choice if you prioritize nonstop international service. Olímpico/Enrique Olaya Herrera Airport (EOH) is the city’s closer, mostly domestic airport that tends to serve regional and low-cost carriers as well as some shorter connections. Sitting within a few minutes of the city center—around 10–20 minutes by taxi—this airport is usually perceived as more budget-friendly for short-haul trips and commuter routes. Ground options typically include taxis and local buses with minimal fares; rides into central neighborhoods can be quick but may be constrained by limited facilities. Pros: proximity to downtown and faster transfers; cons: fewer international flights and more basic passenger services. It’s often the practical choice for quick domestic hops or business travel with tight schedules.
The cheapest flight ticket from Sao Paulo to Medellin according to data for the last 48 hours costs $143
Often the best time to buy tickets from Sao Paulo to Medellin is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Sao Paulo to Medellin can be found flying in these months: February, January, November.
The fastest flights from Sao Paulo to Medellin start from 10 hours in the air.
The following airlines operate direct flights on the route Sao Paulo — Medellin:
In different months, ticket prices from Sao Paulo to Medellin vary: minimum — $145 (February 2026), maximum — $183 (April 2026). Typically, the flight costs $165–$171.
We couldn't find any special offers for flights from Sao Paulo to Medellin
The cheapest one-way flight from Sao Paulo to Medellin departs on 02/10/2026, is operated by Asian Air and costs $143
The cheapest roundtrip flight from Sao Paulo to Medellin departs on 11/05/2026, is operated by LATAM Chile and costs $390
Fastest flight from Sao Paulo to Medellin takes 10 hours
There are no direct flights on this route.
The distance between Sao Paulo and Medellin is 4568km (2832 miles). The average flight duration is 8h 15m. The time difference between Sao Paulo and Medellin is 2h