Cheap Flights from Santiago to Panama City Starting at $252
Helping travelers to find the best flight offers
Cheapest flights from Santiago to Panama City
Cheapest one way flight
$252
Avianca
1 transfer
16 hours
06/28/2025
The cheapest one-way flight from Santiago to Panama City departs on 06/28/2025, is operated by Avianca and costs $252
Cheapest round trip flight
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There is no information about the cheapest roundtrip flight from Santiago to Panama City
The fastest flight
16 hours
Fastest flight from Santiago to Panama City takes 16 hours
Direct flights
No direct flights
There are no direct flights on this route.
Earliest flight
4:11 AM
Latest flight
2:24 AM
Direct flights count
40
Distance
4810km
Timezone difference
1h
The distance between Santiago and Panama City is 4810km (2982 miles).There are 40 direct flights from Santiago to Panama City.The time difference between Santiago and Panama City is 1h .Flights from Santiago begin at 4:11 AM.The latest flight from Santiago departs at 2:24 AM.
Remember that on average the ideal time to book flights is 2 months before departure!
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Santiago to Panama City
June 2025
Lowest price
on average:
$252
Avg Price
Airlines operating on route
Below you will find a list of airlines operating flights on the Santiago — Panama City route and the starting prices for flights of each specific airline on it.
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Santiago to Panama City
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Alternative routes
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Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to Panama City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A direct flight is the most convenient and comfortable way to fly from Santiago to Panama City, despite the fact that sometimes flights with transfers can cost significantly less.
Copa Airlines
Every day
Starting at $982
How much is the cheapest flight ticket from Santiago to Panama City?
The cheapest flight ticket from Santiago to Panama City according to data for the last 48 hours costs $252
When is the best time to buy air tickets on the route Santiago — Panama City?
Often the best time to buy tickets from Santiago to Panama City is 2 months before departure.
When is the cheapest time of year to fly from Santiago to Panama City?
Based on statistics over the past years, the lowest prices for flights from Santiago to Panama City can be found flying in these months: June.
How long does it take to fly from Santiago to Panama City?
The fastest flights from Santiago to Panama City start from 16 hours in the air.
Which airline can fly direct from Santiago to Panama City?
The following airlines operate direct flights on the route Santiago — Panama City: Copa Airlines
