Helping travelers to find the best flight offers
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Panama City:
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to Panama City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Santiago to Panama City
A direct flight is the most convenient and comfortable way to fly from Santiago to Panama City, despite the fact that sometimes flights with transfers can cost significantly less.
Below you will find a list of airlines operating flights on the Santiago — Panama City route and the starting prices for flights of each specific airline on it.
The cheapest one-way flight from Santiago to Panama City departs on 04/28/2025, is operated by Avianca and costs $226
The cheapest roundtrip flight from Santiago to Panama City departs on 03/01/2025, is operated by Avianca and costs $592
Fastest flight from Santiago to Panama City takes 10h 40m
There are no direct flights on this route.
The distance between Santiago and Panama City is 4810km (2982 miles). There are 45 direct flights from Santiago to Panama City. The time difference between Santiago and Panama City is 1h . Flights from Santiago begin at 5:22 AM. The latest flight from Santiago departs at 3:28 AM.
Unable to find information about the schedule of direct flights from
We couldn't find any special offers for flights from Santiago to Panama City
Santiago — Panama City
02/12/2025
Departure date
Direct flight
CM498
Starting at $983
Santiago — Panama City
02/21/2025
Departure date
Direct flight
CM276
Starting at $1,085
Santiago — Panama City
02/22/2025
Departure date
Direct flight
CM174
Starting at $984
Santiago — Panama City
02/28/2025
Departure date
Direct flight
CM498
Starting at $710
Santiago — Panama City
03/01/2025
Departure date
Direct flight
CM276
Starting at $1,097
Santiago — Panama City
03/22/2025
Departure date
Direct flight
CM498
Starting at $831
Santiago — Panama City
03/23/2025
Departure date
Direct flight
CM276
Starting at $676
Santiago — Panama City
03/24/2025
Departure date
Direct flight
CM475
Starting at $572
Santiago — Panama City
03/28/2025
Departure date
Direct flight
CM118
Starting at $831
Santiago — Panama City
03/29/2025
Departure date
Direct flight
CM118
Starting at $734
The cheapest flight ticket from Santiago to Panama City according to data for the last 48 hours costs $226
Often the best time to buy tickets from Santiago to Panama City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Panama City can be found flying in these months: March.
The fastest flights from Santiago to Panama City start from 10 hours 40 minutes in the air.
The following airlines operate direct flights on the route Santiago — Panama City: Copa Airlines
