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A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Cartagena:
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Answers to questions about the route that travelers are most interested in.
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Find the best deals from Santiago to Cartagena with a single search that scans over 700 airlines, 50+ agencies, and more than 5 top booking systems to uncover the cheapest fares, optimal schedules, and flexible ticket conditions. Whether you’re planning a beach getaway or a business trip to Colombia, we make it easy to compare options and book the right flight in minutes.
Santiago is served primarily by Comodoro Arturo Merino Benítez International Airport (SCL), the country’s main international hub and busiest gateway for both full-service carriers and major Latin American airlines; low-cost carriers also operate some routes here. Located about 15–20 km northwest of downtown Santiago, travel to the city center typically takes 20–40 minutes by taxi or ride-hail and can be 30–50 minutes by airport bus or shuttle; fares for buses are usually economical while taxis/ride-hails can be mid-range. The airport offers good transfer connectivity and modern facilities, though peak hours can be crowded and security lines may be longer—overall a convenient option for international and domestic connections across Chile.
Fly direct from Santiago to Cartagena for the fastest, most convenient way to trade Chilean skies for Colombia’s Caribbean charm—no layovers, less hassle, and more time to enjoy the city. While connecting flights can sometimes be cheaper, a direct service saves hours and makes your trip noticeably more comfortable, so consider booking nonstop for a smoother journey.
Rafael Núñez International Airport (CTG) serves Cartagena as the main international gateway and a regional hub for both leisure and business travelers. It typically handles a mix of full-service and low-cost carriers offering domestic connections to Bogotá and Medellín as well as seasonal international flights to the U.S., Canada and Latin America. The airport sits about 3–7 km (10–20 minutes) from the historic center; taxis and ride-hailing are the quickest options with fares generally modest, while buses and hotel shuttles can be cheaper but slower. Pros: compact terminals and short transfer times; cons: can be crowded in peak season and international connectivity is more limited than larger Colombian hubs.
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Santiago to Cartagena
There appear to be no non-stop flights from Santiago to Cartagena at this time.... Well, or something went wrong on our side and we couldn't find anything
starting at $161
You can fly from Santiago to Cartagena with B&H Airlines. It is the only carrier on this route, which makes the choice straightforward. Despite the lack of competition, ticket prices remain affordable: fares start from $161. Our service helps you track price changes, compare by dates, and select the most suitable flight. If you value stability and predictability, flying with B&H Airlines is a convenient solution. We make it easy to find good deals and ensure a comfortable booking process.
The cheapest flight ticket from Santiago to Cartagena according to data for the last 48 hours costs $161
Often the best time to buy tickets from Santiago to Cartagena is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Cartagena can be found flying in these months: January.
The fastest flights from Santiago to Cartagena start from 12 hours 16 minutes in the air.
The following airlines operate direct flights on the route Santiago — Cartagena:
We couldn't find any special offers for flights from Santiago to Cartagena
The cheapest one-way flight from Santiago to Cartagena departs on 04/16/2026, is operated by B&H Airlines and costs $161
The cheapest roundtrip flight from Santiago to Cartagena departs on 07/16/2026, is operated by B&H Airlines and costs $432
Fastest flight from Santiago to Cartagena takes 12h 16m
There are no direct flights on this route.
The distance between Santiago and Cartagena is 4905km (3041 miles). There are 4 direct flights from Santiago to Cartagena. The time difference between Santiago and Cartagena is 1h. Flights from Santiago begin at 5:10 AM. The latest flight from Santiago departs at 5:10 AM