Cheap Flights from Santiago to Cartagena — $283

The Santiago — Cartagena route is served by multiple airlines, including Sky Airline and LATAM Chile. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $283, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.

Find the best deals from Santiago to Cartagena with a single search that scans over 700 airlines, 50+ agencies, and more than 5 top booking systems to uncover the cheapest fares, optimal schedules, and flexible ticket conditions. Whether you’re planning a beach getaway or a business trip to Colombia, we make it easy to compare options and book the right flight in minutes.

Santiago is served primarily by Comodoro Arturo Merino Benítez International Airport (SCL), the country’s main international hub and busiest gateway for both full-service carriers and major Latin American airlines; low-cost carriers also operate some routes here. Located about 15–20 km northwest of downtown Santiago, travel to the city center typically takes 20–40 minutes by taxi or ride-hail and can be 30–50 minutes by airport bus or shuttle; fares for buses are usually economical while taxis/ride-hails can be mid-range. The airport offers good transfer connectivity and modern facilities, though peak hours can be crowded and security lines may be longer—overall a convenient option for international and domestic connections across Chile.

Fly direct from Santiago to Cartagena for the fastest, most convenient way to trade Chilean skies for Colombia’s Caribbean charm—no layovers, less hassle, and more time to enjoy the city. While connecting flights can sometimes be cheaper, a direct service saves hours and makes your trip noticeably more comfortable, so consider booking nonstop for a smoother journey.

Rafael Núñez International Airport (CTG) serves Cartagena as the main international gateway and a regional hub for both leisure and business travelers. It typically handles a mix of full-service and low-cost carriers offering domestic connections to Bogotá and Medellín as well as seasonal international flights to the U.S., Canada and Latin America. The airport sits about 3–7 km (10–20 minutes) from the historic center; taxis and ride-hailing are the quickest options with fares generally modest, while buses and hotel shuttles can be cheaper but slower. Pros: compact terminals and short transfer times; cons: can be crowded in peak season and international connectivity is more limited than larger Colombian hubs.