Cheap Flights from Santiago to Medellin Starting at $135
Helping travelers to find the best flight offers
Cheapest flights from Santiago to Medellin
Fly from Santiago to Medellín with confidence — our search scans over 700 airlines, 50+ agencies and 5+ top booking systems to uncover the best fares, schedules and ticket conditions for your trip. Compare options in seconds and lock in the deal that fits your budget and travel plans.
Remember that on average the ideal time to book flights is 2 months before departure!
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Santiago to Medellin
Airlines operating on route
Direct Flights from Santiago to Medellin
Schedule of direct flights from Santiago to Medellin
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Medellin:
Santiago airports overview
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Medellin airports overview
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Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Santiago to Medellin
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Alternative routes
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Cheapest one way flight
$135
B&H Airlines
Direct flight
6h 15m
02/28/2026
The cheapest one-way flight from Santiago to Medellin departs on 02/28/2026, is operated by B&H Airlines and costs $135
Cheapest round trip flight
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There is no information about the cheapest roundtrip flight from Santiago to Medellin
The fastest flight
6h 15m
Fastest flight from Santiago to Medellin takes 6h 15m
Direct flights
Several times a week
There are direct flights on this route 2 days a week: Mo and Sa
Distance
4440km
Timezone difference
1h
The distance between Santiago and Medellin is 4440km (2753 miles). The time difference between Santiago and Medellin is 1h
January 2026
Lowest price
on average:
$140
Avg Price
Unable to find information about the schedule of direct flights from
More than 4 airlines operate flights from Santiago to Medellin, including B&H Airlines, Jet Ops, Copa Airlines, and LATAM Chile. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $135, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
How much is the cheapest flight ticket from Santiago to Medellin?
The cheapest flight ticket from Santiago to Medellin according to data for the last 48 hours costs $135
When is the best time to buy air tickets on the route Santiago — Medellin?
Often the best time to buy tickets from Santiago to Medellin is 2 months before departure.
When is the cheapest time of year to fly from Santiago to Medellin?
Based on statistics over the past years, the lowest prices for flights from Santiago to Medellin can be found flying in these months: January.
How long does it take to fly from Santiago to Medellin?
The fastest flights from Santiago to Medellin start from 6 hours 15 minutes in the air.
Which airline can fly direct from Santiago to Medellin?
The following airlines operate direct flights on the route Santiago — Medellin: B&H Airlines, Jet Ops
We couldn't find any special offers for flights from Santiago to Medellin
José María Córdova International (MDE) is Medellín’s primary international gateway, serving long-haul and regional carriers including Avianca, LATAM and several low-cost airlines on international routes. Located about 35 km southeast of downtown Medellín in Rionegro, transfers typically take 40–60 minutes by taxi or private shuttle and can be longer in peak traffic; shared vans and airport buses offer cheaper alternatives with fares usually lower than private cars. Expect a more complete set of passenger services and international connections here, though travel time to the city can add cost and complexity. Pros: wide route network and facilities; cons: longer transfer times and occasional congestion.
Olaya Herrera Airport (EOH) functions mainly as Medellín’s domestic and regional airport, handling short-haul flights and turboprops operated by regional carriers. Sitting roughly 4 km from the city center, it is easily reachable by taxi or ride-hail in about 10–20 minutes, with fares typically cheaper than transfers from the international airport. Its compact terminals make for quick check-ins and short walks, but expect fewer amenities and limited international options. Pros: proximity and fast city access; cons: fewer services and airlines compared with the international airport, and smaller aircraft facilities.
Santiago’s main gateway is Comodoro Arturo Merino Benítez International (SCL), the country’s largest international hub handling most long-haul and regional flights and commonly served by full-service carriers as well as several low-cost airlines. It sits about 15–20 km northwest of downtown Santiago, with travel times typically ranging from 20–45 minutes by taxi or ride‑share depending on traffic; airport shuttles and the Line 1 metro extension plus bus services can also connect you in roughly 30–60 minutes for modest fares. A smaller option for private and some domestic traffic can be found at nearby smaller aerodromes. Pros: modern terminal facilities and a wide route network. Cons: peak-hour congestion and distance from the city center can add time and cost to transfers.
Fly nonstop from Santiago to Medellín for the quickest, most convenient way to link Chile’s capital with Colombia’s vibrant city—no layovers, less hassle, and more time to enjoy your trip. While connecting options can sometimes be cheaper, a direct flight saves hours and offers a smoother, more comfortable journey so you arrive refreshed and ready to explore.
