Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to Medellin. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Santiago to Medellin, despite the fact that sometimes flights with transfers can cost significantly less.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
There are most likely no direct flights on the Santiago — Medellin route
Santiago — Medellin
06/12/2026
Departure
Direct flight
JA5839
starting at $368
Santiago — Medellin
09/11/2026
Departure
Direct flight
JA5839
starting at $340
Santiago — Medellin
12/08/2026
Departure
Direct flight
JA5839
starting at $286
starting at $165
starting at $228
Flights from Santiago to Medellin are operated by several airlines — B&H Airlines and Sky Airline. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $165, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.
The cheapest one-way flight from Santiago to Medellin departs on 12/08/2026, is operated by B&H Airlines and costs $165
The cheapest roundtrip flight from Santiago to Medellin departs on 08/27/2026, is operated by B&H Airlines and costs $328
Fastest flight from Santiago to Medellin takes 12h 44m
There are direct flights on this route 2 days a week: Tu and Fr
The distance between Santiago and Medellin is 4440km (2753 miles). The average flight duration is 6h 24m. There are 2 direct flights from Santiago to Medellin. The time difference between Santiago and Medellin is 1h. Flights from Santiago begin at 1:11 AM. The latest flight from Santiago departs at 1:11 AM
Santiago’s main gateway is Comodoro Arturo Merino Benítez International (SCL), the country’s largest international hub handling most long-haul and regional flights and commonly served by full-service carriers as well as several low-cost airlines. It sits about 15–20 km northwest of downtown Santiago, with travel times typically ranging from 20–45 minutes by taxi or ride‑share depending on traffic; airport shuttles and the Line 1 metro extension plus bus services can also connect you in roughly 30–60 minutes for modest fares. A smaller option for private and some domestic traffic can be found at nearby smaller aerodromes. Pros: modern terminal facilities and a wide route network. Cons: peak-hour congestion and distance from the city center can add time and cost to transfers.
José María Córdova International (MDE) is Medellín’s primary international gateway, serving long-haul and regional carriers including Avianca, LATAM and several low-cost airlines on international routes. Located about 35 km southeast of downtown Medellín in Rionegro, transfers typically take 40–60 minutes by taxi or private shuttle and can be longer in peak traffic; shared vans and airport buses offer cheaper alternatives with fares usually lower than private cars. Expect a more complete set of passenger services and international connections here, though travel time to the city can add cost and complexity. Pros: wide route network and facilities; cons: longer transfer times and occasional congestion. Olaya Herrera Airport (EOH) functions mainly as Medellín’s domestic and regional airport, handling short-haul flights and turboprops operated by regional carriers. Sitting roughly 4 km from the city center, it is easily reachable by taxi or ride-hail in about 10–20 minutes, with fares typically cheaper than transfers from the international airport. Its compact terminals make for quick check-ins and short walks, but expect fewer amenities and limited international options. Pros: proximity and fast city access; cons: fewer services and airlines compared with the international airport, and smaller aircraft facilities.
We couldn't find any special offers for flights from Santiago to Medellin
The cheapest flight ticket from Santiago to Medellin according to data for the last 48 hours costs $165
Often the best time to buy tickets from Santiago to Medellin is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Medellin can be found flying in these months: December, September, June.
The fastest flights from Santiago to Medellin start from 12 hours 44 minutes in the air.
The following airlines operate direct flights on the route Santiago — Medellin: B&H Airlines
The cost of a one-way flight from Santiago to Medellin ranges from $165 (December 2026) to $228 (June 2026). On average, the ticket price is about $188–$398.
Good news for anyone planning a flight from Santiago to Medellin: prices are steadily declining. From June 2026 to December 2026, tickets dropped by 28%, and the trend continues.
The most notable drop occurred from June 2026 to December 2026 — down 28%. The best period is September 2026–December 2026 (averaging $167), while the most expensive is June 2026–September 2026 ($199).
Since prices are falling, there's no rush to buy. The most cost-effective travel period is September 2026–December 2026: savings compared to expensive months can reach up to 16%.
Monthly price variation is 15.4%. Choosing the right departure date can lead to significant savings on this route.