Iberia
Tu, Th, and Sa
starting at $1,057
LATAM Chile
Tu, We, Th, Fr, and Sa
starting at $1,064
Compare airlines, prices, and flight durations for your trip
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to Madrid. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
The cost of a one-way flight from Santiago to Madrid ranges from $415 (June 2026) to $625 (September 2026). On average, the ticket price is about $511–$548.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Madrid:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Iberia
Tu, Th, and Sa
starting at $1,057
LATAM Chile
Tu, We, Th, Fr, and Sa
starting at $1,064
Santiago — Madrid
04/01/2026
Departure
Direct flight
LA708
starting at $1,187
Santiago — Madrid
04/08/2026
Departure
Direct flight
LA714
starting at $1,119
Santiago — Madrid
04/10/2026
Departure
Direct flight
LA706
starting at $1,703
Santiago — Madrid
04/17/2026
Departure
Direct flight
LA714
starting at $1,933
Santiago — Madrid
04/22/2026
Departure
Direct flight
IB118
starting at $895
Santiago — Madrid
04/29/2026
Departure
Direct flight
IB6585
starting at $968
Santiago — Madrid
05/02/2026
Departure
Direct flight
LA714
starting at $2,620
Santiago — Madrid
07/11/2026
Departure
Direct flight
LA5410
starting at $1,349
Santiago — Madrid
01/11/2027
Departure
Direct flight
LA706
starting at $1,146
Santiago — Madrid
01/12/2027
Departure
Direct flight
LA706
starting at $1,146
starting at $489
starting at $895
starting at $606
starting at $701
starting at $725
starting at $781
starting at $900
More than 7 airlines operate flights from Santiago to Madrid, including LATAM Chile, Iberia, Avianca, Air Canada, Sky Airline, Air Ocean, and Copa Airlines. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $489, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
The cheapest flight ticket from Santiago to Madrid according to data for the last 48 hours costs $489
Often the best time to buy tickets from Santiago to Madrid is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Madrid can be found flying in these months: June, April, March.
The fastest flights from Santiago to Madrid start from 12 hours 55 minutes in the air.
The following airlines operate direct flights on the route Santiago — Madrid: LATAM Chile, Iberia
The cheapest one-way flight from Santiago to Madrid departs on 06/30/2026, is operated by LATAM Chile and costs $489
The cheapest roundtrip flight from Santiago to Madrid departs on 01/17/2027, is operated by Air Canada and costs $963
Fastest flight from Santiago to Madrid takes 12h 55m
There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa
The distance between Santiago and Madrid is 10691km (6628 miles). The average flight duration is 16h. There are 34 direct flights from Santiago to Madrid. The time difference between Santiago and Madrid is 5h. Flights from Santiago begin at 1:05 PM. The latest flight from Santiago departs at 11:55 PM
A non-stop flight is the most convenient and comfortable way to fly from Santiago to Madrid, despite the fact that sometimes flights with transfers can cost significantly less.
We couldn't find any special offers for flights from Santiago to Madrid
