Iberia
Every day
starting at $719
Compare airlines, prices, and flight durations for your trip
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to Madrid. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Madrid:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Iberia
Every day
starting at $719
Santiago — Madrid
01/14/2026
Departure
Direct flight
IB118
starting at $1,675
Santiago — Madrid
01/15/2026
Departure
Direct flight
LA6652
starting at $2,077
Santiago — Madrid
01/17/2026
Departure
Direct flight
LA8
starting at $1,299
Santiago — Madrid
01/18/2026
Departure
Direct flight
LA6652
starting at $1,326
Santiago — Madrid
01/22/2026
Departure
Direct flight
IB6652
starting at $1,034
Santiago — Madrid
01/23/2026
Departure
Direct flight
LA6652
starting at $998
Santiago — Madrid
01/24/2026
Departure
Direct flight
LA6652
starting at $1,291
Santiago — Madrid
02/01/2026
Departure
Direct flight
LA706
starting at $1,074
Santiago — Madrid
02/03/2026
Departure
Direct flight
LA706
starting at $809
Santiago — Madrid
02/13/2026
Departure
Direct flight
LA6652
starting at $908
starting at $669
starting at $498
starting at $459
starting at $571
starting at $586
starting at $651
starting at $720
starting at $776
More than 8 airlines operate flights from Santiago to Madrid, including Iberia, LATAM Chile, United Airlines, Avianca, Sky Airline, Air Ocean, Air Canada, and Asian Air. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $459, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
The cheapest one-way flight from Santiago to Madrid departs on 01/25/2026, is operated by United Airlines and costs $459
The cheapest roundtrip flight from Santiago to Madrid departs on 02/07/2026, is operated by Air Canada and costs $725
Fastest flight from Santiago to Madrid takes 23 hours
There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa
The distance between Santiago and Madrid is 10691km (6628 miles). The average flight duration is 12h 55m. There are 55 direct flights from Santiago to Madrid. The time difference between Santiago and Madrid is 5h. Flights from Santiago begin at 11:55 AM. The latest flight from Santiago departs at 11:55 PM
A non-stop flight is the most convenient and comfortable way to fly from Santiago to Madrid, despite the fact that sometimes flights with transfers can cost significantly less.
The cheapest flight ticket from Santiago to Madrid according to data for the last 48 hours costs $459
Often the best time to buy tickets from Santiago to Madrid is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Madrid can be found flying in these months: January, February, March.
The fastest flights from Santiago to Madrid start from 23 hours in the air.
The following airlines operate direct flights on the route Santiago — Madrid: Iberia, LATAM Chile
The cost of a one-way flight from Santiago to Madrid ranges from $451 (January 2026) to $601 (May 2026). On average, the ticket price is about $510–$538.
