Helping travelers to find the best flight offers
Fly from Santiago to Istanbul with confidence — our search scans over 700 airlines, 50+ agencies and 5+ top booking systems to uncover the best prices, schedules and booking conditions for your trip. Compare options in seconds and lock in the flight that fits your budget and timing for a seamless journey to Turkey’s vibrant gateway.
Fly nonstop from Santiago to Istanbul for the fastest, most convenient way to bridge South America and Europe—arrive sooner and skip the hassle of layovers. While connecting flights can sometimes be cheaper, a direct service saves hours and offers a more relaxed journey so you can start exploring Istanbul refreshed and on schedule.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Istanbul:
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We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The cheapest one-way flight from Santiago to Istanbul departs on 12/04/2025, is operated by LATAM Chile and costs $468
The cheapest roundtrip flight from Santiago to Istanbul departs on 03/06/2026, is operated by Iberia and costs $1,169
Fastest flight from Santiago to Istanbul takes 1d 0h 30m
There are no direct flights on this route.
The distance between Santiago and Istanbul is 13078km (8108 miles). The average flight duration is 18h 5m. There are 4 direct flights from Santiago to Istanbul. The time difference between Santiago and Istanbul is 7h. Flights from Santiago begin at 10:45 AM. The latest flight from Santiago departs at 11:40 AM
The route Santiago — Istanbul is served by many carriers — 9 in total, including Turkish Airlines, LATAM Chile, Avianca, United Airlines, Iberia, Sky Airline, B&H Airlines, Jatayu Airlines, and Asian Air. This gives passengers wide opportunities: from finding the lowest fare (from $468) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.
Starting at $997
Starting at $468
Starting at $545
Starting at $554
Starting at $557
Starting at $608
Starting at $653
Starting at $694
Starting at $725
Santiago — Istanbul
11/02/2025
Departure
Direct flight
TK216
Starting at $1,273
Santiago — Istanbul
11/04/2025
Departure
Direct flight
TK216
Starting at $1,186
Santiago — Istanbul
11/06/2025
Departure
Direct flight
TK216
Starting at $1,186
Santiago — Istanbul
11/27/2025
Departure
Direct flight
TK216
Starting at $1,170
Santiago — Istanbul
11/30/2025
Departure
Direct flight
TK216
Starting at $997
Santiago — Istanbul
12/02/2025
Departure
Direct flight
TK216
Starting at $1,198
Santiago — Istanbul
12/04/2025
Departure
Direct flight
TK216
Starting at $1,179
Santiago — Istanbul
12/05/2025
Departure
Direct flight
TK216
Starting at $1,165
Santiago — Istanbul
12/09/2025
Departure
Direct flight
TK216
Starting at $1,165
Santiago — Istanbul
12/16/2025
Departure
Direct flight
TK216
Starting at $1,914
Turkish Airlines
Su, Tu, Th, and Fr
Starting at $1,225
Arturo Merino Benítez International Airport (SCL) is Santiago’s main international gateway and typically functions as the country’s premium hub, handling most long-haul and regional flights with carriers such as LATAM, Sky Airline and JetSMART operating frequent services. Located about 15–20 km northwest of downtown Santiago, transfer times can be roughly 20–40 minutes by taxi or ride-share depending on traffic, and 30–40 minutes by the airport bus; expect fares to usually range from moderate to slightly higher for taxis and modest for public shuttles. The airport tends to offer a wide choice of lounges, duty-free shopping and multiple dining options, which can make it convenient for international connections, though peak-hour road congestion and occasional waits at immigration can be downsides for fast transfers.
Istanbul Airport (IST) is the city’s large international hub, serving long-haul, regional and transfer traffic and hosting major carriers such as Turkish Airlines alongside many full-service international airlines. Located about 40–50 km northwest of the historic centre, transfers to Taksim or Sultanahmet can take 40–70 minutes by car depending on traffic. Options include Havaist and IETT airport buses (fares typically moderate), taxi rides and a growing metro connection that shortens journey times. Pros: modern facilities, extensive flight choices and good transfer infrastructure; cons: longer transfer distances and occasional heavy traffic to central districts. Sabiha Gökçen International Airport (SAW) operates primarily as a secondary international and low-cost gateway on Istanbul’s Asian side, favoured by budget carriers and many charter flights. It sits roughly 35–45 km southeast of the historic peninsula, with road transfers to Kadıköy or central Istanbul taking about 45–75 minutes depending on traffic and route. Transport choices include Havatas/Havabus shuttle services, municipal buses, taxis and some private shuttles; fares tend to be economical for bus options. Pros: often cheaper fares and quicker access for Asian-side neighbourhoods; cons: fewer long-haul connections and longer journeys to European-side attractions.
We couldn't find any special offers for flights from Santiago to Istanbul
The cheapest flight ticket from Santiago to Istanbul according to data for the last 48 hours costs $468
Often the best time to buy tickets from Santiago to Istanbul is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Istanbul can be found flying in these months: November, October, February.
The fastest flights from Santiago to Istanbul start from 30 minutes in the air.
The following airlines operate direct flights on the route Santiago — Istanbul: Turkish Airlines, LATAM Chile
In different months, ticket prices from Santiago to Istanbul vary: minimum — $493 (November 2025), maximum — $647 (May 2026). Typically, the flight costs $543–$1,062.