Compare airlines, prices, and flight durations for your trip
Fly from Santiago to Istanbul with confidence — our search scans over 700 airlines, 50+ agencies and 5+ top booking systems to uncover the best prices, schedules and booking conditions for your trip. Compare options in seconds and lock in the flight that fits your budget and timing for a seamless journey to Turkey’s vibrant gateway.
In different months, ticket prices from Santiago to Istanbul vary: minimum — $549 (February 2026), maximum — $859 (July 2026). Typically, the flight costs $737–$1,517.
Fly nonstop from Santiago to Istanbul for the fastest, most convenient way to bridge South America and Europe—arrive sooner and skip the hassle of layovers. While connecting flights can sometimes be cheaper, a direct service saves hours and offers a more relaxed journey so you can start exploring Istanbul refreshed and on schedule.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Istanbul:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The cheapest one-way flight from Santiago to Istanbul departs on 02/28/2026, is operated by United Airlines and costs $531
The cheapest roundtrip flight from Santiago to Istanbul departs on 02/17/2026, is operated by Air France and costs $1,098
Fastest flight from Santiago to Istanbul takes 1d 1h 25m
There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa
The distance between Santiago and Istanbul is 13078km (8108 miles). The average flight duration is 20h 2m. There are 5 direct flights from Santiago to Istanbul. The time difference between Santiago and Istanbul is 7h. Flights from Santiago begin at 11:30 AM. The latest flight from Santiago departs at 11:40 AM
The route Santiago — Istanbul is served by many carriers — 11 in total, including Turkish Airlines, United Airlines, Copa Airlines, LATAM Chile, Avianca, Sky Airline, British Airways, B&H Airlines, Air Canada, Iberia, and Miami Air International. This gives passengers wide opportunities: from finding the lowest fare (from $531) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.
starting at $801
starting at $531
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starting at $707
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starting at $796
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Santiago — Istanbul
02/12/2026
Departure
Direct flight
TK216
starting at $1,174
Santiago — Istanbul
03/01/2026
Departure
Direct flight
TK216
starting at $2,012
Santiago — Istanbul
06/08/2026
Departure
Direct flight
TK216
starting at $1,189
Santiago — Istanbul
07/01/2026
Departure
Direct flight
TK216
starting at $1,233
Santiago — Istanbul
07/02/2026
Departure
Direct flight
TK216
starting at $1,181
Santiago — Istanbul
02/17/2026
Departure
Direct flight
TK216
starting at $1,185
Santiago — Istanbul
02/19/2026
Departure
Direct flight
TK216
starting at $1,263
Santiago — Istanbul
02/21/2026
Departure
Direct flight
TK216
starting at $1,188
Santiago — Istanbul
02/22/2026
Departure
Direct flight
TK216
starting at $1,244
Santiago — Istanbul
02/24/2026
Departure
Direct flight
TK216
starting at $1,237
Turkish Airlines
Su, Tu, Th, and Fr
starting at $828
Arturo Merino Benítez International Airport (SCL) is Santiago’s main international gateway and typically functions as the country’s premium hub, handling most long-haul and regional flights with carriers such as LATAM, Sky Airline and JetSMART operating frequent services. Located about 15–20 km northwest of downtown Santiago, transfer times can be roughly 20–40 minutes by taxi or ride-share depending on traffic, and 30–40 minutes by the airport bus; expect fares to usually range from moderate to slightly higher for taxis and modest for public shuttles. The airport tends to offer a wide choice of lounges, duty-free shopping and multiple dining options, which can make it convenient for international connections, though peak-hour road congestion and occasional waits at immigration can be downsides for fast transfers.
The cheapest flight ticket from Santiago to Istanbul according to data for the last 48 hours costs $531
Often the best time to buy tickets from Santiago to Istanbul is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Istanbul can be found flying in these months: February, May, March.
The fastest flights from Santiago to Istanbul start from 1 hour 25 minutes in the air.
The following airlines operate direct flights on the route Santiago — Istanbul: Turkish Airlines
Istanbul Airport (IST) is the city’s large international hub, serving long-haul, regional and transfer traffic and hosting major carriers such as Turkish Airlines alongside many full-service international airlines. Located about 40–50 km northwest of the historic centre, transfers to Taksim or Sultanahmet can take 40–70 minutes by car depending on traffic. Options include Havaist and IETT airport buses (fares typically moderate), taxi rides and a growing metro connection that shortens journey times. Pros: modern facilities, extensive flight choices and good transfer infrastructure; cons: longer transfer distances and occasional heavy traffic to central districts. Sabiha Gökçen International Airport (SAW) operates primarily as a secondary international and low-cost gateway on Istanbul’s Asian side, favoured by budget carriers and many charter flights. It sits roughly 35–45 km southeast of the historic peninsula, with road transfers to Kadıköy or central Istanbul taking about 45–75 minutes depending on traffic and route. Transport choices include Havatas/Havabus shuttle services, municipal buses, taxis and some private shuttles; fares tend to be economical for bus options. Pros: often cheaper fares and quicker access for Asian-side neighbourhoods; cons: fewer long-haul connections and longer journeys to European-side attractions.