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Fly from Santiago to Cape Town with confidence—our search scans over 700 airlines, 50+ agencies and more than 5 top booking systems to uncover the best prices, schedules and travel conditions tailored to you. Compare nonstop and connecting options in seconds and lock in the deal that fits your dates and budget.
Fly direct from Santiago to Cape Town for the fastest, most convenient way to connect South America and South Africa—saving hours and avoiding the hassle of layovers so you can start exploring sooner. While some connecting options may be cheaper, a nonstop flight gives you extra comfort and time savings worth considering when planning your trip.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Cape Town:
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Answers to questions about the route that travelers are most interested in.
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Unable to find information about the schedule of direct flights from
Arturo Merino Benítez Airport (SCL) is Santiago’s main international gateway and typically functions as Chile’s principal long-haul and regional hub, serving legacy carriers and many international airlines alongside low-cost operators. Located about 20 km northwest of downtown Santiago, travel to the city center can take roughly 20–40 minutes by taxi or private transfer depending on traffic, with fares usually in the moderate range; public buses and airport shuttles offer cheaper options that can take around 30–60 minutes. The airport generally provides a full set of passenger amenities and frequent connections, though peak-time congestion and occasional security queues can affect comfort; it’s a convenient choice for international itineraries while budget-conscious travelers can find cheaper ground-transport alternatives.
There appear to be no non-stop flights from Santiago to Cape Town at this time.... Well, or something went wrong on our side and we couldn't find anything
starting at $633
You can fly from Santiago to Cape Town with LATAM Chile. It is the only carrier on this route, which makes the choice straightforward. Despite the lack of competition, ticket prices remain affordable: fares start from $633. Our service helps you track price changes, compare by dates, and select the most suitable flight. If you value stability and predictability, flying with LATAM Chile is a convenient solution. We make it easy to find good deals and ensure a comfortable booking process.
The cheapest one-way flight from Santiago to Cape Town departs on 03/18/2026, is operated by LATAM Chile and costs $633
There is no information about the cheapest roundtrip flight from Santiago to Cape Town
Fastest flight from Santiago to Cape Town takes 1d 0h 5m
There are no direct flights on this route.
The distance between Santiago and Cape Town is 7945km (4926 miles). The time difference between Santiago and Cape Town is 6h
Cape Town International is South Africa’s main gateway to the Western Cape and usually serves as the city’s international and regional hub, handling full-service carriers as well as low-cost airlines. The airport sits about 20–25 km (roughly 30–40 minutes by road) from the city centre, with transfer options including MyCiTi express buses (around 30–40 minutes), metered taxis or ride-hailing services (25–45 minutes) and private shuttles; fares can vary widely depending on service level. Domestic flights are frequent and can be competitively priced compared with long-haul connections. Pros: modern terminal amenities and good international connectivity; cons: peak-hour congestion and occasional traffic delays on the N2/M3 approaches.
We couldn't find any special offers for flights from Santiago to Cape Town
The cheapest flight ticket from Santiago to Cape Town according to data for the last 48 hours costs $633
Often the best time to buy tickets from Santiago to Cape Town is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Cape Town can be found flying in these months: March.
The fastest flights from Santiago to Cape Town start from 5 minutes in the air.
The following airlines operate direct flights on the route Santiago — Cape Town:
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Santiago to Cape Town