Schedule of direct flights from Saint Louis to Chicago
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Saint Louis to Chicago:
Saint Louis airports overview
Chicago airports overview
Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Saint Louis to Chicago
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Alternative routes
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Cheapest one way flight
$47
American Airlines
Direct flight
1h 20m
04/07/2025
The cheapest one-way flight from Saint Louis to Chicago departs on 04/07/2025, is operated by American Airlines and costs $47
The cheapest roundtrip flight from Saint Louis to Chicago departs on 03/24/2025, is operated by Executive Express Aviation LLC dbaSouthern Airways and costs $207
The fastest flight
1h 20m
Fastest flight from Saint Louis to Chicago takes 1h 20m
Direct flights
Several times a week
There are direct flights on this route 2 days a week: Mo and Th
Earliest flight
6:25 AM
Latest flight
8:25 PM
Direct flights count
31
Distance
422km
Timezone difference
0h
The distance between Saint Louis and Chicago is 422km (262 miles).There are 31 direct flights from Saint Louis to Chicago.Saint Louis and Chicago are in the same time zone.Flights from Saint Louis begin at 6:25 AM.The latest flight from Saint Louis departs at 8:25 PM.
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Saint Louis to Chicago
A direct flight is the most convenient and comfortable way to fly from Saint Louis to Chicago, despite the fact that sometimes flights with transfers can cost significantly less.
Unable to find information about the schedule of direct flights from
July 2025
Lowest price
on average:
$107
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Saint Louis to Chicago. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
Below you will find a list of airlines operating flights on the Saint Louis — Chicago route and the starting prices for flights of each specific airline on it.
Saint Louis — Chicago
STL — CHI
03/17/2025
Departure date
Direct flight
UA2424
Starting at $282
Saint Louis — Chicago
STL — CHI
03/20/2025
Departure date
Direct flight
WN540
Starting at $85
Saint Louis — Chicago
STL — CHI
04/07/2025
Departure date
Direct flight
WN554
Starting at $167
Saint Louis — Chicago
STL — CHI
04/07/2025
Departure date
Direct flight
AA2923
Starting at $47
Saint Louis — Chicago
STL — CHI
06/18/2025
Departure date
Direct flight
AA6324
Starting at $153
Saint Louis — Chicago
STL — CHI
07/12/2025
Departure date
Direct flight
UA4399
Starting at $259
Saint Louis — Chicago
STL — CHI
07/13/2025
Departure date
Direct flight
UA4423
Starting at $197
How much is the cheapest flight ticket from Saint Louis to Chicago?
The cheapest flight ticket from Saint Louis to Chicago according to data for the last 48 hours costs $47
When is the best time to buy air tickets on the route Saint Louis — Chicago?
Often the best time to buy tickets from Saint Louis to Chicago is 2 months before departure.
When is the cheapest time of year to fly from Saint Louis to Chicago?
Based on statistics over the past years, the lowest prices for flights from Saint Louis to Chicago can be found flying in these months: July.
How long does it take to fly from Saint Louis to Chicago?
The fastest flights from Saint Louis to Chicago start from 1 hour 20 minutes in the air.
Which airline can fly direct from Saint Louis to Chicago?
The following airlines operate direct flights on the route Saint Louis — Chicago: United Airlines, Southwest Airlines, American Airlines
