Helping travelers to find the best flight offers
Fly from Istanbul to Panama City with confidence — our search scans over 700 airlines, 50+ travel agencies and more than 5 top booking systems to uncover the best prices, timetables and travel conditions for your trip. Compare routes and fares in seconds and book the option that fits your schedule and budget with ease.
The cost of a one-way flight from Istanbul to Panama City ranges from $471 (November 2025) to $641 (April 2026). On average, the ticket price is about $542–$1,095.
Fly nonstop from Istanbul to Panama City for the quickest, most hassle-free way to bridge continents—direct flights cut out layovers so you arrive sooner and more relaxed. While connecting options can sometimes be cheaper, choosing a direct route saves valuable time and adds comfort to long-haul travel, making it easy to focus on your trip instead of transfers.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Istanbul to Panama City:
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
More than 12 airlines operate flights from Istanbul to Panama City, including Turkish Airlines, British Airways, Valuair, Pegasus Airlines, Vueling, Wizz Air, Transavia, Wizz Air, Air Europa, Aegean Airlines, FlyOne, and East African Safari Air. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $496, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
Starting at $538
Starting at $496
Starting at $505
Starting at $512
Starting at $532
Starting at $569
Starting at $590
Starting at $610
Starting at $617
Starting at $631
Starting at $634
Starting at $760
Istanbul — Panama City
10/23/2025
Departure
Direct flight
TK801
Starting at $4,601
Istanbul — Panama City
10/24/2025
Departure
Direct flight
TK800
Starting at $4,607
Istanbul — Panama City
10/25/2025
Departure
Direct flight
TK801
Starting at $5,942
Istanbul — Panama City
10/26/2025
Departure
Direct flight
TK800
Starting at $4,529
Istanbul — Panama City
10/27/2025
Departure
Direct flight
TK903
Starting at $5,198
Istanbul — Panama City
10/28/2025
Departure
Direct flight
TK900
Starting at $4,615
Istanbul — Panama City
10/29/2025
Departure
Direct flight
TK903
Starting at $6,131
Istanbul — Panama City
10/30/2025
Departure
Direct flight
TK801
Starting at $4,539
Istanbul — Panama City
10/31/2025
Departure
Direct flight
TK800
Starting at $4,599
Istanbul — Panama City
11/01/2025
Departure
Direct flight
TK903
Starting at $4,615
Turkish Airlines
Su, Mo, Tu, We, Th, and Fr
Starting at $1,272
Istanbul has two main airports serving different market segments. Istanbul Airport (IST) is the city’s primary international hub, handling most long-haul and full-service carriers and often positioned as a premium gateway; it sits about 35–50 km northwest of the historic center, with airport shuttle buses, taxis and Havaist coaches typically taking 40–60 minutes depending on traffic and costing roughly mid-range compared with other European airports. Sabiha Gökçen (SAW), on the Asian side, tends to be favoured by low-cost and regional airlines and can be seen as more budget-friendly for many travelers; it’s around 45–60 km from central Sultanahmet, with express buses, Havabus shuttles and taxis taking 60–90 minutes and usually offering lower fares but longer transfers. Pros: IST offers extensive international connections and modern facilities; SAW can be cheaper and convenient for Asian-side destinations. Cons: both can involve lengthy transfers in peak traffic, and inter-airport transfers may add significant time and cost.
The cheapest flight ticket from Istanbul to Panama City according to data for the last 48 hours costs $496
Often the best time to buy tickets from Istanbul to Panama City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Istanbul to Panama City can be found flying in these months: November, October, January.
The fastest flights from Istanbul to Panama City start from 3 hours 15 minutes in the air.
The following airlines operate direct flights on the route Istanbul — Panama City: Turkish Airlines
The cheapest one-way flight from Istanbul to Panama City departs on 01/13/2026, is operated by British Airways and costs $496
The cheapest roundtrip flight from Istanbul to Panama City departs on 02/18/2026, is operated by Air Europa and costs $890
Fastest flight from Istanbul to Panama City takes 1d 3h 15m
There are no direct flights on this route.
The distance between Istanbul and Panama City is 10850km (6727 miles). The average flight duration is 14h 37m. There are 11 direct flights from Istanbul to Panama City. The time difference between Istanbul and Panama City is 8h. Flights from Istanbul begin at 8:00 AM. The latest flight from Istanbul departs at 2:20 PM
Tocumen International (PTY) is Panama City’s main international hub and typically handles the bulk of long-haul and regional flights, serving major carriers and many Latin American and North American connections. It’s located about 24 km (15 miles) east of downtown, with taxi and ride-hail journeys usually taking 25–40 minutes depending on traffic and costing roughly USD 25–40; an express airport bus and shared shuttles can be cheaper options but may take longer. Flights to smaller domestic destinations sometimes use Albrook Marcos A. Gelabert (PAC) closer to the city center (about 2–3 km), which is typically favored by local and budget carriers and can be more convenient for short-haul travel. Tocumen offers greater international connectivity and amenities, while Albrook is often quicker for downtown access but has fewer long-haul services.
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American Airlines