Cheap Flights from Chicago to Saint Louis

Cheapest flights from Chicago to Saint Louis

Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Chicago to Saint Louis. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.

Cheapest one way flight

$120

Frontier Airlines

1 transfer

1d 8h 7m

12/08/2025

The cheapest one-way flight from Chicago to Saint Louis departs on 12/08/2025, is operated by Frontier Airlines and costs $120

Cheapest round trip flight

—

There is no information about the cheapest roundtrip flight from Chicago to Saint Louis

The fastest flight

1h 21m

Fastest flight from Chicago to Saint Louis takes 1h 21m

Direct flights

Once a week

There are direct flights on this route 1 day a week: We

Earliest flight

6:45 AM

Latest flight

10:34 PM

Direct flights count

107

Distance

422km

Timezone difference

0h

The distance between Chicago and Saint Louis is 422km (262 miles). There are 107 direct flights from Chicago to Saint Louis. Chicago and Saint Louis are in the same time zone. Flights from Chicago begin at 6:45 AM. The latest flight from Chicago departs at 10:34 PM

Remember that on average the ideal time to book flights is 2 months before departure!

Airfare from Chicago to Saint Louis by month

The cost of a one-way flight from Chicago to Saint Louis ranges from $120 (December 2025) to $135 (March 2026). On average, the ticket price is about $127–$135.

December 2025

Lowest price

on average:

$120

March 2026

Highest price

on average:

$135

Avg Price

Airlines operating on route

More than 5 airlines operate flights from Chicago to Saint Louis, including American Airlines, Southwest Airlines, SkyWest Airlines, United Airlines, and Frontier Airlines. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $120, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.

Starting at $154

Starting at $329

Starting at $180

Starting at $270

Starting at $120

Direct Flights from Chicago to Saint Louis

A direct flight is the most convenient and comfortable way to fly from Chicago to Saint Louis, despite the fact that sometimes flights with transfers can cost significantly less.

Chicago — Saint Louis

CHI — STL

12/02/2025

Departure

Direct flight

AA4595

Starting at $154

Chicago — Saint Louis

CHI — STL

12/08/2025

Departure

Direct flight

WN4355

Starting at $329

Chicago — Saint Louis

CHI — STL

03/06/2026

Departure

Direct flight

OO6388

Starting at $180

Chicago — Saint Louis

CHI — STL

03/12/2026

Departure

Direct flight

UA4596

Starting at $270

Schedule of direct flights from Chicago to Saint Louis

A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Chicago to Saint Louis:

Unable to find information about the schedule of direct flights from

Chicago airports overview

Merrill C Meigs

•

CGX

3km

Former single-runway general aviation facility on Chicago’s lakefront adjacent to downtown, serving business and private flights until its abrupt closure in 2003.

DuPage Airport

•

DPA

52km

General aviation reliever near Chicago in West Chicago, Illinois, serving corporate, private and flight-training traffic with hangars, FBO services and maintenance, convenient for access to the western suburbs.

Chicago Midway International Airport

•

MDW

14km

Serving Chicago’s Southwest Side and downtown, it handles mainly domestic flights with a strong presence of low-cost carriers and easy connections via the 'L' Orange Line and nearby expressways.

O'Hare International Airport

•

ORD

26km

Chicago Executive Airport

•

PWK

35km

Chicago Rockford International Airport

•

RFD

140km

Serving Rockford and northern Illinois, the airport handles domestic passenger flights and is a major cargo hub. Convenient ground links provide access to the Chicago metro and surrounding communities.

•

Saint Louis airports overview

Lambert-St. Louis International Airport

•

STL

20km

Spirit of St. Louis Airport

•

SUS

20km

•

Frequently asked questions (FAQ)

Answers to questions about the route that travelers are most interested in.

How much is the cheapest flight ticket from Chicago to Saint Louis?

The cheapest flight ticket from Chicago to Saint Louis according to data for the last 48 hours costs $120

When is the best time to buy air tickets on the route Chicago — Saint Louis?

Often the best time to buy tickets from Chicago to Saint Louis is 2 months before departure.

When is the cheapest time of year to fly from Chicago to Saint Louis?

Based on statistics over the past years, the lowest prices for flights from Chicago to Saint Louis can be found flying in these months: December, March.

How long does it take to fly from Chicago to Saint Louis?

The fastest flights from Chicago to Saint Louis start from 1 hour 21 minutes in the air.

Which airline can fly direct from Chicago to Saint Louis?

The following airlines operate direct flights on the route Chicago — Saint Louis: American Airlines, Southwest Airlines, SkyWest Airlines

Special offers and sales on air tickets from Chicago to Saint Louis

We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.

We couldn't find any special offers for flights from Chicago to Saint Louis

Alternative routes

Appleton ➜ Saint Louis•Kalamazoo ➜ Saint Louis•Champaign ➜ Saint Louis•Fort Wayne ➜ Saint Louis•Indianapolis ➜ Saint Louis•Lansing ➜ Saint Louis•Milwaukee ➜ Saint Louis•Muskegon ➜ Saint Louis•South Bend ➜ Saint Louis•Chicago ➜ Nashville•Chicago ➜ Burlington•Chicago ➜ Chicago•Chicago ➜ Cedar Rapids•Chicago ➜ Champaign•Chicago ➜ Evansville•Chicago ➜ Indianapolis•Chicago ➜ Memphis

•••••••••••••••••••

Cheapest one way flight

$120

Frontier Airlines

1 transfer

1d 8h 7m

12/08/2025

The cheapest one-way flight from Chicago to Saint Louis departs on 12/08/2025, is operated by Frontier Airlines and costs $120

Cheapest round trip flight

—

There is no information about the cheapest roundtrip flight from Chicago to Saint Louis

The fastest flight