Cheap Flights from Cancun to Panama City Starting at $146
Helping travelers to find the best flight offers
Cheapest flights from Cancun to Panama City
Fly from Cancun to Panama City with confidence — our search scans over 700 airlines, 50+ agencies and 5+ top booking systems to uncover the best prices, schedules and ticket conditions for your trip. Friendly, fast comparisons help you pick the ideal flight so you can spend less time hunting deals and more time planning Panama’s adventures.
Remember that on average the ideal time to book flights is 2 months before departure!
The cost of a one-way flight from Cancun to Panama City ranges from $152 (March 2026) to $320 (April 2026). On average, the ticket price is about $228–$503.
Airlines operating on route
Direct Flights from Cancun to Panama City
Fly nonstop from Cancun to Panama City for the quickest, most convenient way to get between these tropical hubs — less time in transit means more time exploring Panama’s vibrant nightlife and canal sights. While connecting options can sometimes come cheaper, a direct flight saves hours, reduces hassle and gives you a more comfortable travel experience, perfect for short getaways or tight itineraries.
Schedule of direct flights from Cancun to Panama City
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Cancun to Panama City:
Cancun airports overview
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Panama City airports overview
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Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Cancun to Panama City
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Alternative routes
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Cheapest one way flight
$146
Avianca
1 transfer
14h 25m
12/24/2025
The cheapest one-way flight from Cancun to Panama City departs on 12/24/2025, is operated by Avianca and costs $146
Cheapest round trip flight
$280
Aeromexico
1 transfer
1d 15h 39m
01/11/2026
The cheapest roundtrip flight from Cancun to Panama City departs on 01/11/2026, is operated by Aeromexico and costs $280
The fastest flight
6h 35m
Fastest flight from Cancun to Panama City takes 6h 35m
Direct flights
No direct flights
There are no direct flights on this route.
Earliest flight
7:00 AM
Latest flight
4:42 PM
Direct flights count
47
Distance
1554km
Timezone difference
0h
The distance between Cancun and Panama City is 1554km (963 miles). There are 47 direct flights from Cancun to Panama City. Cancun and Panama City are in the same time zone. Flights from Cancun begin at 7:00 AM. The latest flight from Cancun departs at 4:42 PM
March 2026
Lowest price
on average:
$152
April 2026
Highest price
on average:
$320
Avg Price
Flights from Cancun to Panama City are operated by several airlines — Copa Airlines, Avianca, and Aerolíneas Mas. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $146, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.
Cancún International Airport (CUN) is the main gateway for the Riviera Maya and serves as a large international hub, handling a mix of full-service and leisure carriers as well as many low-cost and charter flights. It’s located about 16 km (roughly 20–40 minutes) from downtown Cancún and 20–80 minutes from popular hotel zones, depending on traffic; taxis, shared shuttles and private transfers are common, with shuttle fares typically lower than private rides. The airport has multiple terminals with basic to modern amenities and on-site car rental desks. Pros: extensive international connections and plentiful transfer options. Cons: busy peak-season crowds and occasional longer queues for immigration and baggage.
How much is the cheapest flight ticket from Cancun to Panama City?
The cheapest flight ticket from Cancun to Panama City according to data for the last 48 hours costs $146
When is the best time to buy air tickets on the route Cancun — Panama City?
Often the best time to buy tickets from Cancun to Panama City is 2 months before departure.
When is the cheapest time of year to fly from Cancun to Panama City?
Based on statistics over the past years, the lowest prices for flights from Cancun to Panama City can be found flying in these months: March, February, January.
How long does it take to fly from Cancun to Panama City?
The fastest flights from Cancun to Panama City start from 6 hours 35 minutes in the air.
Which airline can fly direct from Cancun to Panama City?
The following airlines operate direct flights on the route Cancun — Panama City: Copa Airlines
We couldn't find any special offers for flights from Cancun to Panama City
Tocumen International Airport (PTY) is Panama City’s main international gateway and a major connecting hub for flights across the Americas, with a mix of full-service carriers and regional airlines handling most long-haul and transit traffic. Located about 24 km (roughly 30–45 minutes) east of downtown via the Corredor Norte or the Pan-American Highway, public buses, airport shuttles and taxis are common — expect shuttle or taxi rides to cost typically more than local buses. There’s also limited rapid transit connections planned or in development. Pros: extensive international connections, modern facilities and good transit options for transfers. Cons: can be busy during peak hours and travel times to the city center depend on traffic.
