Cheap Flights from Cancun to Panama City — $131

Fly from Cancun to Panama City with confidence — our search scans over 700 airlines, 50+ agencies and 5+ top booking systems to uncover the best prices, schedules and ticket conditions for your trip. Friendly, fast comparisons help you pick the ideal flight so you can spend less time hunting deals and more time planning Panama’s adventures.

The cost of a one-way flight from Cancun to Panama City ranges from $145 (February 2026) to $242 (January 2026). On average, the ticket price is about $193–$242.

Cancún International Airport (CUN) is the main gateway for the Riviera Maya and serves as a large international hub, handling a mix of full-service and leisure carriers as well as many low-cost and charter flights. It’s located about 16 km (roughly 20–40 minutes) from downtown Cancún and 20–80 minutes from popular hotel zones, depending on traffic; taxis, shared shuttles and private transfers are common, with shuttle fares typically lower than private rides. The airport has multiple terminals with basic to modern amenities and on-site car rental desks. Pros: extensive international connections and plentiful transfer options. Cons: busy peak-season crowds and occasional longer queues for immigration and baggage.

Fly nonstop from Cancun to Panama City for the quickest, most convenient way to get between these tropical hubs — less time in transit means more time exploring Panama’s vibrant nightlife and canal sights. While connecting options can sometimes come cheaper, a direct flight saves hours, reduces hassle and gives you a more comfortable travel experience, perfect for short getaways or tight itineraries.

More than 6 airlines operate flights from Cancun to Panama City, including Copa Airlines, Avianca, Spirit Airlines, VivaAerobus, Aeromexico, and Aerolíneas Mas. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $131, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.

Tocumen International Airport (PTY) is Panama City’s main international gateway and a major connecting hub for flights across the Americas, with a mix of full-service carriers and regional airlines handling most long-haul and transit traffic. Located about 24 km (roughly 30–45 minutes) east of downtown via the Corredor Norte or the Pan-American Highway, public buses, airport shuttles and taxis are common — expect shuttle or taxi rides to cost typically more than local buses. There’s also limited rapid transit connections planned or in development. Pros: extensive international connections, modern facilities and good transit options for transfers. Cons: can be busy during peak hours and travel times to the city center depend on traffic.