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Find great deals from San Pedro Sula to Panama City with our fast, friendly search — we scan over 700 airlines, 50+ travel agencies and 5+ top booking systems to bring you the best prices, schedules and travel conditions. Compare nonstop and connecting options in seconds and book confidently knowing you’re getting the most complete market view for this popular Central America route.
Fly nonstop from San Pedro Sula to Panama City for the quickest, most convenient way to get between these vibrant Central American hubs — less time in transit means more time exploring Panama’s skyline and canals. While connecting options can sometimes be cheaper, a direct flight saves hours, reduces hassle and usually delivers a more comfortable travel experience.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from San Pedro Sula to Panama City:
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The cheapest one-way flight from San Pedro Sula to Panama City departs on 09/23/2026, is operated by Avianca and costs $205
There is no information about the cheapest roundtrip flight from San Pedro Sula to Panama City
Fastest flight from San Pedro Sula to Panama City takes 4h 20m
There are no direct flights on this route.
The distance between San Pedro Sula and Panama City is 1161km (720 miles). There are 12 direct flights from San Pedro Sula to Panama City. The time difference between San Pedro Sula and Panama City is 1h. Flights from San Pedro Sula begin at 4:28 AM. The latest flight from San Pedro Sula departs at 1:49 PM
You can fly from San Pedro Sula to Panama City with Avianca. It is the only carrier on this route, which makes the choice straightforward. Despite the lack of competition, ticket prices remain affordable: fares start from $205. Our service helps you track price changes, compare by dates, and select the most suitable flight. If you value stability and predictability, flying with Avianca is a convenient solution. We make it easy to find good deals and ensure a comfortable booking process.
Starting at $205
There appear to be no direct flights from San Pedro Sula to Panama City at this time.... Well, or something went wrong on our side and we couldn't find anything
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Ramón Villeda Morales International Airport (SAP) serves San Pedro Sula as Honduras’s main international gateway and a regional hub for both full-service and low-cost carriers, with frequent flights to the U.S., Central America and occasional South American connections. Fares can lean budget-friendly on low-cost carriers but overall pricing varies by season. The airport sits about 15–20 km east of downtown (roughly 20–35 minutes by car), with public buses and shared shuttles available for modest fares, taxis and private transfers that are quicker but costlier. Pros: relatively compact terminal and regular international connections; cons: can be busy at peak times and amenities are more limited than larger international hubs.
Tocumen International (PTY) serves as Panama City’s main international gateway and regional hub, handling most long-haul and intercontinental flights alongside Latin American carriers and major global airlines; it can feel busy but offers a wide range of services and lounges. The airport sits about 15–25 km east of the city center, with drive times typically 20–40 minutes depending on traffic. Options include taxis or ride‑hailing (fare ranges often moderate), airport shuttles and private transfers; local buses are cheaper but slower. Pros: extensive connections and modern facilities; cons: peak-hour congestion and longer transfer walks. For low‑cost domestic links, smaller regional airports and carriers operate separately within Panama.
We couldn't find any special offers for flights from San Pedro Sula to Panama City
The cheapest flight ticket from San Pedro Sula to Panama City according to data for the last 48 hours costs $205
Often the best time to buy tickets from San Pedro Sula to Panama City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from San Pedro Sula to Panama City can be found flying in these months: February.
The fastest flights from San Pedro Sula to Panama City start from 4 hours 20 minutes in the air.
The following airlines operate direct flights on the route San Pedro Sula — Panama City:
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from San Pedro Sula to Panama City