There are most likely no direct flights on the Guatemala City — Panama City route
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Guatemala City to Panama City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
In different months, ticket prices from Guatemala City to Panama City vary: minimum — $158 (November 2026), maximum — $357 (January 2027). Typically, the flight costs $310–$698.
A non-stop flight is the most convenient and comfortable way to fly from Guatemala City to Panama City, despite the fact that sometimes flights with transfers can cost significantly less.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Flight costs from Guatemala City to Panama City climb toward the middle of the period, then start to drop. By choosing the right dates, you can save noticeably.
Prices rise from November 2026 to February 2027 (+126%), then decline from February 2027 to July 2027 (5%). The cheapest tickets are in November 2026–January 2027 (averaging $258), while the priciest are in January 2027–February 2027 ($357).
For savings, plan your flight for November 2026–January 2027 — you could save up to 28%. Try to avoid January 2027–February 2027 when possible: prices are at their highest then.
Price spread on this route is 24.7%. Costs depend heavily on the season, so flexibility in choosing your departure month is especially valuable here.
There are most likely no direct flights on the Guatemala City — Panama City route
All airports
Guatemala City — Panama City
10/28/2026
Departure
Direct flight
CM183
starting at $341
Guatemala City — Panama City
11/03/2026
Departure
Direct flight
CM407
starting at $329
Guatemala City — Panama City
11/16/2026
Departure
Direct flight
CM384
starting at $422
Guatemala City — Panama City
11/17/2026
Departure
Direct flight
CM111
starting at $339
Guatemala City — Panama City
11/25/2026
Departure
Direct flight
CM407
starting at $383
Guatemala City — Panama City
11/26/2026
Departure
Direct flight
CM392
starting at $475
Guatemala City — Panama City
11/27/2026
Departure
Direct flight
CM384
starting at $473
Guatemala City — Panama City
11/28/2026
Departure
Direct flight
CM389
starting at $357
Guatemala City — Panama City
12/01/2026
Departure
Direct flight
CM407
starting at $359
Guatemala City — Panama City
12/04/2026
Departure
Direct flight
CM539
starting at $359
The Guatemala City — Panama City route is served by multiple airlines, including Copa Airlines, Avianca, and TACA Airlines. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $314, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.
The cheapest flight ticket from Guatemala City to Panama City according to data for the last 48 hours costs $314
Often the best time to buy tickets from Guatemala City to Panama City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Guatemala City to Panama City can be found flying in these months: November, March, July.
The fastest flights from Guatemala City to Panama City start from 2 hours 27 minutes in the air.
The following airlines operate direct flights on the route Guatemala City — Panama City: Copa Airlines
The cheapest one-way flight from Guatemala City to Panama City departs on 10/28/2026, is operated by Avianca and costs $314
There is no information about the cheapest roundtrip flight from Guatemala City to Panama City
Fastest flight from Guatemala City to Panama City takes 2h 27m
There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa
The distance between Guatemala City and Panama City is 1349km (836 miles). There are 46 direct flights from Guatemala City to Panama City. The time difference between Guatemala City and Panama City is 1h. Flights from Guatemala City begin at 4:23 AM. The latest flight from Guatemala City departs at 2:28 AM
We couldn't find any special offers for flights from Guatemala City to Panama City
