Airlines operating on route
Starting at $104
Starting at $131
Helping travelers to find the best flight offers
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Guatemala City to Panama City
Starting at $104
Starting at $131
Guatemala City — Panama City
02/11/2026
Departure date
Direct flight
CM407
Starting at $607
Guatemala City — Panama City
02/24/2026
Departure date
Direct flight
CM384
Starting at $536
Guatemala City — Panama City
02/25/2026
Departure date
Direct flight
CM392
Starting at $536
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Guatemala City to Panama City:
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Below you will find a list of airlines operating flights on the Guatemala City — Panama City route and the starting prices for flights of each specific airline on it.
Unable to find information about the schedule of direct flights from
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Guatemala City to Panama City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A direct flight is the most convenient and comfortable way to fly from Guatemala City to Panama City, despite the fact that sometimes flights with transfers can cost significantly less.
The cheapest flight ticket from Guatemala City to Panama City according to data for the last 48 hours costs $140
Often the best time to buy tickets from Guatemala City to Panama City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Guatemala City to Panama City can be found flying in these months: August, March, May.
The fastest flights from Guatemala City to Panama City start from 8 hours 10 minutes in the air.
The following airlines operate direct flights on the route Guatemala City — Panama City: Copa Airlines
The cheapest one-way flight from Guatemala City to Panama City departs on 02/25/2026, is operated by Avianca and costs $140
The cheapest roundtrip flight from Guatemala City to Panama City departs on 06/10/2025, is operated by Avianca and costs $206
Fastest flight from Guatemala City to Panama City takes 8h 10m
There are no direct flights on this route.
The distance between Guatemala City and Panama City is 1349km (836 miles). There are 41 direct flights from Guatemala City to Panama City. The time difference between Guatemala City and Panama City is 1h . Flights from Guatemala City begin at 4:23 AM. The latest flight from Guatemala City departs at 4:23 PM.
We couldn't find any special offers for flights from Guatemala City to Panama City
