Cheap Flights from Guatemala City to Panama City Starting at $135
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Cheapest flights from Guatemala City to Panama City
Fly from Guatemala City to Panama City with confidence — our search scans over 700 airlines, 50+ agencies, and 5+ top booking systems to uncover the best prices, schedules, and travel conditions for your trip. Compare nonstop and connecting options side-by-side and lock in the flight that fits your budget and timing in just a few clicks.
Remember that on average the ideal time to book flights is 2 months before departure!
Airfare from Guatemala City to Panama City by month
Airlines operating on route
Direct Flights from Guatemala City to Panama City
Fly nonstop from Guatemala City to Panama City for the fastest, most convenient way to connect Central America’s vibrant capitals — less time in transit means more time to explore Panama’s Canal, beaches and nightlife. While connecting flights can sometimes be cheaper, a direct option saves hours and offers a more comfortable, hassle-free journey worth the upgrade.
Schedule of direct flights from Guatemala City to Panama City
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Guatemala City to Panama City:
Guatemala City airports overview
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Panama City airports overview
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Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Guatemala City to Panama City
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Alternative routes
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Cheapest one way flight
$135
Avianca
1 transfer
8 hours
12/06/2025
The cheapest one-way flight from Guatemala City to Panama City departs on 12/06/2025, is operated by Avianca and costs $135
Cheapest round trip flight
$207
Aviateca
1 transfer
17h 30m
03/15/2026
The cheapest roundtrip flight from Guatemala City to Panama City departs on 03/15/2026, is operated by Aviateca and costs $207
The fastest flight
2h 24m
Fastest flight from Guatemala City to Panama City takes 2h 24m
Direct flights
Several times a week
There are direct flights on this route 3 days a week: Su, Fr, and Sa
Earliest flight
4:22 AM
Latest flight
3:59 AM
Direct flights count
46
Distance
1349km
Timezone difference
1h
The distance between Guatemala City and Panama City is 1349km (836 miles). There are 46 direct flights from Guatemala City to Panama City. The time difference between Guatemala City and Panama City is 1h. Flights from Guatemala City begin at 4:22 AM. The latest flight from Guatemala City departs at 3:59 AM
The Guatemala City — Panama City route is served by multiple airlines, including Copa Airlines and Avianca. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $135, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.
La Aurora International Airport (GUA) in Guatemala City is the country’s primary international gateway and typically serves as a hub for full-service carriers alongside regional and low-cost airlines. It sits about 6–10 km south of the historic center, with taxi rides usually taking 15–30 minutes depending on traffic and costing roughly USD 6–15; airport shuttles and app-based ride services are commonly available too. Buses can be cheaper but slower. The terminal is compact and generally convenient for transfers, though peak-hour congestion and security lines can extend wait times. Overall it’s a practical choice for international and domestic connections, balancing accessibility with occasional urban traffic delays.
Tocumen International Airport (PTY) serves Panama City as the country’s main international gateway and a regional connecting hub, favored by full-service carriers and many long-haul flights. It’s about 24 km (roughly 30–45 minutes) from Panama City’s downtown by road; taxis and ride-hailing are common (fares typically fall in a mid-range band), while airport buses and private shuttles offer cheaper fixed-price options for longer transfers. Domestic flights commonly use Marcos A. Gelabert Airport (PAC), closer to the city center for short hops. PTY is convenient for international connections and has extensive amenities, though congestion and longer walk times can be drawbacks; PAC is quicker for local travel but has fewer facilities and fewer airline choices.
How much is the cheapest flight ticket from Guatemala City to Panama City?
The cheapest flight ticket from Guatemala City to Panama City according to data for the last 48 hours costs $135
When is the best time to buy air tickets on the route Guatemala City — Panama City?
Often the best time to buy tickets from Guatemala City to Panama City is 2 months before departure.
When is the cheapest time of year to fly from Guatemala City to Panama City?
Based on statistics over the past years, the lowest prices for flights from Guatemala City to Panama City can be found flying in these months: December.
How long does it take to fly from Guatemala City to Panama City?
The fastest flights from Guatemala City to Panama City start from 2 hours 24 minutes in the air.
Which airline can fly direct from Guatemala City to Panama City?
The following airlines operate direct flights on the route Guatemala City — Panama City: Copa Airlines
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Guatemala City to Panama City
We couldn't find any special offers for flights from Guatemala City to Panama City
