Airlines operating on route
Starting at $96
Starting at $113
Starting at $123
Starting at $163
Helping travelers to find the best flight offers
Starting at $96
Starting at $113
Starting at $123
Starting at $163
Santiago — Sao Paulo
10/22/2025
Departure
Direct flight
H2610
Starting at $96
Santiago — Sao Paulo
10/05/2025
Departure
Direct flight
H2610
Starting at $98
Santiago — Sao Paulo
11/15/2025
Departure
Direct flight
H2610
Starting at $99
Santiago — Sao Paulo
10/19/2025
Departure
Direct flight
H2604
Starting at $112
Santiago — Sao Paulo
09/28/2025
Departure
Direct flight
LA8201
Starting at $113
Santiago — Sao Paulo
08/13/2025
Departure
Direct flight
JA770
Starting at $123
Santiago — Sao Paulo
08/16/2025
Departure
Direct flight
JA770
Starting at $124
Santiago — Sao Paulo
08/22/2025
Departure
Direct flight
JA770
Starting at $125
Santiago — Sao Paulo
10/23/2025
Departure
Direct flight
H2610
Starting at $130
Santiago — Sao Paulo
11/08/2025
Departure
Direct flight
H2610
Starting at $130
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Sao Paulo:
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The cheapest one-way flight from Santiago to Sao Paulo departs on 10/22/2025, is operated by Sky Airline and costs $96
The cheapest roundtrip flight from Santiago to Sao Paulo departs on 11/21/2025, is operated by Sky Airline and costs $170
Fastest flight from Santiago to Sao Paulo takes 3h 45m
There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa
The distance between Santiago and Sao Paulo is 2566km (1591 miles). The average flight duration is 3h 46m. There are 143 direct flights from Santiago to Sao Paulo. The time difference between Santiago and Sao Paulo is 1h . Flights from Santiago begin at 5:02 AM. The latest flight from Santiago departs at 12:37 AM.
The cheapest flight ticket from Santiago to Sao Paulo according to data for the last 48 hours costs $96
Often the best time to buy tickets from Santiago to Sao Paulo is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Sao Paulo can be found flying in these months: October, November, August.
The fastest flights from Santiago to Sao Paulo start from 3 hours 45 minutes in the air.
The following airlines operate direct flights on the route Santiago — Sao Paulo: Sky Airline, LATAM Chile, B&H Airlines
LATAM Chile
Every day
Starting at $292
Sky Airline
Every day
Starting at $98
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to Sao Paulo. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Santiago to Sao Paulo
Below you will find a list of airlines operating flights on the Santiago — Sao Paulo route and the starting prices for flights of each specific airline on it.
A direct flight is the most convenient and comfortable way to fly from Santiago to Sao Paulo, despite the fact that sometimes flights with transfers can cost significantly less.
We couldn't find any special offers for flights from Santiago to Sao Paulo