Cheap Flights from Santiago to Sao Paulo Starting at $121
Helping travelers to find the best flight offers
Cheapest flights from Santiago to Sao Paulo
Fly from Santiago to São Paulo with confidence — our search scans over 700 airlines, 50+ agencies and 5+ top booking systems to uncover the best prices, schedules and travel conditions for your trip. Compare options in seconds and book the flight that matches your budget and timing with ease.
Remember that on average the ideal time to book flights is 2 months before departure!
Fly direct from Santiago to São Paulo for the quickest, most comfortable way to bridge Chile and Brazil—no layovers, less hassle, and more time on the ground enjoying your destination. While connecting options can sometimes be cheaper, a nonstop route saves hours and reduces travel stress, making it a smart choice for business trips or short getaways—check fares now to find the best direct option.
Schedule of direct flights from Santiago to Sao Paulo
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Sao Paulo:
Santiago airports overview
Sao Paulo airports overview
Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Santiago to Sao Paulo
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Alternative routes
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Cheapest one way flight
$121
LATAM Chile
Direct flight
3h 55m
10/24/2025
The cheapest one-way flight from Santiago to Sao Paulo departs on 10/24/2025, is operated by LATAM Chile and costs $121
Cheapest round trip flight
$230
Turkish Airlines
Direct flight
8h 5m
11/27/2025
The cheapest roundtrip flight from Santiago to Sao Paulo departs on 11/27/2025, is operated by Turkish Airlines and costs $230
The fastest flight
3h 45m
Fastest flight from Santiago to Sao Paulo takes 3h 45m
Direct flights
Several times a week
There are direct flights on this route 6 days a week: Su, Tu, We, Th, Fr, and Sa
Earliest flight
6:05 AM
Latest flight
1:40 AM
Average flight duration
4h
Direct flights count
91
Distance
2566km
Timezone difference
1h
The distance between Santiago and Sao Paulo is 2566km (1591 miles). The average flight duration is 4h. There are 91 direct flights from Santiago to Sao Paulo. The time difference between Santiago and Sao Paulo is 1h. Flights from Santiago begin at 6:05 AM. The latest flight from Santiago departs at 1:40 AM
November 2025
Lowest price
on average:
$102
January 2026
Highest price
on average:
$150
Avg Price
More than 6 airlines operate flights from Santiago to Sao Paulo, including LATAM Chile, Sky Airline, LATAM Paraguay, LATAM Brasil, Aerolineas Argentinas, and Avianca. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $121, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
Arturo Merino Benítez Airport (SCL) is Santiago’s main international gateway and typically functions as a full-service hub for LATAM and other legacy carriers, while also handling a growing number of low-cost and regional flights. Located about 15–20 km northwest of downtown, travel time is usually 20–40 minutes by car depending on traffic; airport buses and shared shuttles can take 30–60 minutes and typically cost in the low single-digit to low double-digit USD-equivalent range. Ride-hailing and taxis are widely available for faster but pricier transfers. Pros: broad international connectivity, modern facilities and frequent scheduled services; cons: peak-hour congestion and longer transit times to central Santiago can be factors to weigh.
São Paulo is served mainly by three airports, each playing a distinct role. São Paulo–Guarulhos International (GRU) is the primary international hub, handling most long-haul and full-service carriers; it’s about 25–30 km from downtown São Paulo and typically reachable in 30–60 minutes by airport bus, taxi or app ride (fares vary widely), or by the commuter rail + airport bus combination for lower cost. Congonhas (CGH) functions as the city’s domestic/business gateway for short-haul flights and legacy carriers, sitting roughly 8–9 km from the center — a taxi or ride-share often takes 20–40 minutes depending on traffic, while buses offer cheaper if slower options. Viracopos (VCP), near Campinas and farther out (around 90–110 km from São Paulo), can be a lower-cost or cargo-focused alternative used by some international budget or charter services; coach transfers and regional buses connect it to the city in about 90–120 minutes. Pros: GRU offers extensive international connections and amenities; Congonhas is convenient for central access and business travel; Viracopos may yield cheaper fares or less congestion. Cons: GRU can be far and busy during peak times; Congonhas is subject to heavy road traffic; Viracopos involves a long ground transfer. Typical transport fares range from budget shuttle/bus options to higher taxi/app prices, so travelers often balance cost versus door-to-door time.
We couldn't find any special offers for flights from Santiago to Sao Paulo
How much is the cheapest flight ticket from Santiago to Sao Paulo?
The cheapest flight ticket from Santiago to Sao Paulo according to data for the last 48 hours costs $121
When is the best time to buy air tickets on the route Santiago — Sao Paulo?
Often the best time to buy tickets from Santiago to Sao Paulo is 2 months before departure.
When is the cheapest time of year to fly from Santiago to Sao Paulo?
Based on statistics over the past years, the lowest prices for flights from Santiago to Sao Paulo can be found flying in these months: November, October, December.
How long does it take to fly from Santiago to Sao Paulo?
The fastest flights from Santiago to Sao Paulo start from 3 hours 45 minutes in the air.
Which airline can fly direct from Santiago to Sao Paulo?
The following airlines operate direct flights on the route Santiago — Sao Paulo: LATAM Chile, Sky Airline
The cost of a one-way flight from Santiago to Sao Paulo ranges from $102 (November 2025) to $150 (January 2026). On average, the ticket price is about $125–$256.
