Compare airlines, prices, and flight durations for your trip
Fly from Santiago to Quito with confidence — our search scans over 700 airlines, 50+ agencies and more than five leading booking systems to uncover the best prices, schedules and travel conditions for your trip. Compare nonstop and multi-stop options in seconds and lock in the ideal fare and itinerary for exploring Ecuador’s highlands.
Fly non-stop from Santiago to Quito for the fastest, most convenient way to link Chile’s capital with Ecuador’s highland gem — fewer hassles, no layovers, and more time to enjoy your trip. While connecting options can sometimes be cheaper, a direct flight saves time and adds comfort, making it the smart choice for busy travelers and those wanting a smoother journey.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Quito:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The Santiago — Quito route is served by multiple airlines, including B&H Airlines, Copa Airlines, and LATAM Chile. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $118, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.
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Santiago is primarily served by Comodoro Arturo Merino Benítez International Airport (SCL), the country’s main international hub and largest airport for both full-service and low-cost carriers. Major airlines and several regional carriers typically operate long-haul and domestic routes here, so fares can range from budget-friendly to premium depending on season and carrier. The airport sits about 15–20 km northwest of downtown Santiago; drivers usually take 20–40 minutes depending on traffic. Transport options include official airport taxis, shared shuttles and app-based rides (fares vary), a public bus service with cheaper tickets, and a recently extended metro line connection that can take around 30–50 minutes to the central area. Pros: well-equipped international facilities and many airline choices. Cons: can be busy at peak times and road transfers may be slowed by city traffic.
Mariscal Sucre International Airport (UIO) serves Quito as the country’s primary international gateway and a regional hub for carriers such as Avianca, LATAM and local airlines including TAME’s successors; it usually handles the bulk of long-haul and connecting services. Located about 18–18.5 km east of the historic center (new airport, about 30–40 minutes by road in normal traffic), transport options typically include taxis or ride-hailing (roughly 25–40 USD), airport shuttles and occasional bus lines (lower cost, longer journey). The facility can be convenient for international transfers but may feel busy at peak times; fares and travel times are subject to traffic and service variation. For budget travelers, Quito’s bus and shuttle choices can be the most economical.
The cheapest flight ticket from Santiago to Quito according to data for the last 48 hours costs $118
Often the best time to buy tickets from Santiago to Quito is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Quito can be found flying in these months: March, July, February.
The fastest flights from Santiago to Quito start from 8 hours 15 minutes in the air.
The following airlines operate direct flights on the route Santiago — Quito:
In different months, ticket prices from Santiago to Quito vary: minimum — $157 (March 2026), maximum — $243 (June 2026). Typically, the flight costs $193–$198.
We couldn't find any special offers for flights from Santiago to Quito
The cheapest one-way flight from Santiago to Quito departs on 06/12/2026, is operated by B&H Airlines and costs $118
The cheapest roundtrip flight from Santiago to Quito departs on 02/14/2026, is operated by Copa Airlines and costs $703
Fastest flight from Santiago to Quito takes 8h 15m
There are no direct flights on this route.
The distance between Santiago and Quito is 3791km (2350 miles). The average flight duration is 8h 20m. The time difference between Santiago and Quito is 1h
