There are most likely no direct flights on the Santiago — Guayaquil route
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to Guayaquil. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Santiago to Guayaquil
A non-stop flight is the most convenient and comfortable way to fly from Santiago to Guayaquil, despite the fact that sometimes flights with transfers can cost significantly less.
•
•
•
•
•
•
Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
There are most likely no direct flights on the Santiago — Guayaquil route
All airports
Santiago — Guayaquil
11/30/2026
Departure
Direct flight
XL1446
starting at $343
Santiago — Guayaquil
12/01/2026
Departure
Direct flight
XL1446
starting at $739
Santiago — Guayaquil
11/18/2026
Departure
Direct flight
LA1446
starting at $258
The route Santiago — Guayaquil is served by several airlines: LATAM Ecuador, LATAM Chile, and Copa Airlines. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $234 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.
The cheapest flight ticket from Santiago to Guayaquil according to data for the last 48 hours costs $234
Often the best time to buy tickets from Santiago to Guayaquil is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Guayaquil can be found flying in these months: October.
The fastest flights from Santiago to Guayaquil start from 9 hours 59 minutes in the air.
The following airlines operate direct flights on the route Santiago — Guayaquil: LATAM Ecuador, LATAM Chile
The cheapest one-way flight from Santiago to Guayaquil departs on 11/18/2026, is operated by Copa Airlines and costs $234
The cheapest roundtrip flight from Santiago to Guayaquil departs on 12/21/2026, is operated by Copa Airlines and costs $593
Fastest flight from Santiago to Guayaquil takes 9h 59m
There are direct flights on this route 3 days a week: Mo, Tu, and We
The distance between Santiago and Guayaquil is 3605km (2235 miles). There are 8 direct flights from Santiago to Guayaquil. The time difference between Santiago and Guayaquil is 1h. Flights from Santiago begin at 12:45 AM. The latest flight from Santiago departs at 12:45 AM
We couldn't find any special offers for flights from Santiago to Guayaquil