Starting at $210
Starting at $288
Helping travelers to find the best flight offers
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Guayaquil:
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Starting at $210
Starting at $288
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Santiago to Guayaquil
A direct flight is the most convenient and comfortable way to fly from Santiago to Guayaquil, despite the fact that sometimes flights with transfers can cost significantly less.
Santiago — Guayaquil
01/24/2025
Departure date
Direct flight
LA1446
Starting at $544
Santiago — Guayaquil
01/31/2025
Departure date
Direct flight
LA1446
Starting at $528
Santiago — Guayaquil
02/27/2025
Departure date
Direct flight
LA1446
Starting at $207
Santiago — Guayaquil
03/07/2025
Departure date
Direct flight
LA1446
Starting at $185
Santiago — Guayaquil
05/20/2025
Departure date
Direct flight
LA1446
Starting at $279
Santiago — Guayaquil
11/07/2025
Departure date
Direct flight
LA1446
Starting at $294
The cheapest flight ticket from Santiago to Guayaquil according to data for the last 48 hours costs $185
Often the best time to buy tickets from Santiago to Guayaquil is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Guayaquil can be found flying in these months: February.
The fastest flights from Santiago to Guayaquil start from 5 hours 16 minutes in the air.
The following airlines operate direct flights on the route Santiago — Guayaquil: LATAM Chile
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to Guayaquil. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
Below you will find a list of airlines operating flights on the Santiago — Guayaquil route and the starting prices for flights of each specific airline on it.
LATAM Chile
Every day
Starting at $185
The cheapest one-way flight from Santiago to Guayaquil departs on 03/07/2025, is operated by LATAM Chile and costs $185
The cheapest roundtrip flight from Santiago to Guayaquil departs on 03/07/2025, is operated by LATAM Chile and costs $394
Fastest flight from Santiago to Guayaquil takes 5h 16m
There are direct flights on this route 1 day a week: Fr
The distance between Santiago and Guayaquil is 3610km (2238 miles). The average flight duration is 5h 16m. There are 8 direct flights from Santiago to Guayaquil. The time difference between Santiago and Guayaquil is 1h . Flights from Santiago begin at 12:45 AM. The latest flight from Santiago departs at 12:45 AM.
We couldn't find any special offers for flights from Santiago to Guayaquil
