Cheap Flights from Santiago to Mexico City — $273

Fly nonstop from Santiago to Mexico City for the quickest, most convenient way to bridge South and Central America — arrive sooner and skip the hassle of layovers. While you may sometimes find cheaper connecting options, a direct flight saves hours and keeps your trip more comfortable, making it a smart choice for business or leisure travel.

The route Santiago — Mexico City is served by many carriers — 9 in total, including Aeromexico, LATAM Chile, Wamos Air, B&H Airlines, Jatayu Airlines, Asian Air, Sky Airline, Avianca, and Copa Airlines. This gives passengers wide opportunities: from finding the lowest fare (from $273) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.

Comodoro Arturo Merino Benítez Airport (SCL) is Santiago’s main international gateway and typically serves as Chile’s primary hub for full-service carriers and many long-haul flights, while also handling some low-cost operators. It sits about 15–20 km northwest of downtown Santiago; road transfer by taxi or rideshare can take roughly 20–40 minutes depending on traffic, with airport buses and shared shuttles usually offering cheaper options in the 30–90 minute range overall. A suburban metro extension and bus connections provide budget-friendly access, though transfer times vary. Pros: comprehensive facilities, many international connections and frequent airline choices. Cons: can be busy during peak hours and traffic to the city can be unpredictable.

Mexico City’s main gateway is Benito Juárez International Airport (MEX), the country’s primary international hub handling a mix of full-service and low-cost carriers; it typically serves most long-haul and domestic flights. Located about 8–13 km east of the historic center, travel times to downtown can range from 20–60 minutes depending on traffic. Options include the metro (Line 5 and transfer connections) and the newer airport bus and Aerotren links, with fares usually low to moderate, while taxis and rideshares are faster but can cost more. Pros: extensive connections and amenities; cons: can be crowded and subject to traffic delays during peak hours. There are also smaller general-aviation fields and military airbases around the metropolitan area for private or charter operations.

In different months, ticket prices from Santiago to Mexico City vary: minimum — $190 (March 2026), maximum — $388 (June 2026). Typically, the flight costs $310–$337.