Cheap Flights from Santiago to Mexico City Starting at $229

Comodoro Arturo Merino Benítez Airport (SCL) is Santiago’s main international gateway and typically serves as Chile’s primary hub for full-service carriers and many long-haul flights, while also handling some low-cost operators. It sits about 15–20 km northwest of downtown Santiago; road transfer by taxi or rideshare can take roughly 20–40 minutes depending on traffic, with airport buses and shared shuttles usually offering cheaper options in the 30–90 minute range overall. A suburban metro extension and bus connections provide budget-friendly access, though transfer times vary. Pros: comprehensive facilities, many international connections and frequent airline choices. Cons: can be busy during peak hours and traffic to the city can be unpredictable.

Fly nonstop from Santiago to Mexico City for the quickest, most convenient way to bridge South and Central America — arrive sooner and skip the hassle of layovers. While you may sometimes find cheaper connecting options, a direct flight saves hours and keeps your trip more comfortable, making it a smart choice for business or leisure travel.

Mexico City’s main gateway is Benito Juárez International Airport (MEX), the country’s primary international hub handling a mix of full-service and low-cost carriers; it typically serves most long-haul and domestic flights. Located about 8–13 km east of the historic center, travel times to downtown can range from 20–60 minutes depending on traffic. Options include the metro (Line 5 and transfer connections) and the newer airport bus and Aerotren links, with fares usually low to moderate, while taxis and rideshares are faster but can cost more. Pros: extensive connections and amenities; cons: can be crowded and subject to traffic delays during peak hours. There are also smaller general-aviation fields and military airbases around the metropolitan area for private or charter operations.

In different months, ticket prices from Santiago to Mexico City vary: minimum — $234 (February 2026), maximum — $339 (June 2026). Typically, the flight costs $277–$596.

The route Santiago — Mexico City is served by many carriers — 6 in total, including Aeromexico, LATAM Chile, Jatayu Airlines, Sky Airline, Asian Air, and Copa Airlines. This gives passengers wide opportunities: from finding the lowest fare (from $229) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.