Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to Mexico City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Santiago to Mexico City, despite the fact that sometimes flights with transfers can cost significantly less.
The only airline operating direct flights from Santiago to Mexico City is LATAM Chile. Flights operate on Wednesday and Saturday.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The cheapest one-way flight from Santiago to Mexico City departs on 06/17/2026, is operated by Sky Airline and costs $266
The cheapest roundtrip flight from Santiago to Mexico City departs on 06/09/2026, is operated by LATAM Chile and costs $653
Fastest flight from Santiago to Mexico City takes 11h 14m
There are direct flights on this route 6 days a week: Su, Mo, Tu, Th, Fr, and Sa
The distance between Santiago and Mexico City is 6611km (4099 miles). The average flight duration is 30m. There are 3 direct flights from Santiago to Mexico City. The time difference between Santiago and Mexico City is 2h. Flights from Santiago begin at 8:30 AM. The latest flight from Santiago departs at 8:30 AM
The route Santiago — Mexico City is served by many carriers — 9 in total, including LATAM Chile, Wamos Air, Aeromexico, Sky Airline, Asian Air, Jatayu Airlines, B&H Airlines, Copa Airlines, and Avianca. This gives passengers wide opportunities: from finding the lowest fare (from $266) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.
starting at $915
starting at $981
starting at $787
starting at $266
starting at $304
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starting at $363
starting at $385
starting at $409
Santiago — Mexico City
06/02/2026
Departure
Direct flight
LA622
starting at $981
Santiago — Mexico City
06/07/2026
Departure
Direct flight
LA622
starting at $1,046
Santiago — Mexico City
06/14/2026
Departure
Direct flight
LA622
starting at $1,166
Santiago — Mexico City
07/11/2026
Departure
Direct flight
LA622
starting at $975
Santiago — Mexico City
09/10/2026
Departure
Direct flight
LA622
starting at $1,013
Santiago — Mexico City
09/12/2026
Departure
Direct flight
EB622
starting at $981
Santiago — Mexico City
09/26/2026
Departure
Direct flight
LA622
starting at $1,202
Santiago — Mexico City
09/27/2026
Departure
Direct flight
EB622
starting at $1,073
Santiago — Mexico City
12/03/2026
Departure
Direct flight
AM11
starting at $840
Santiago — Mexico City
12/04/2026
Departure
Direct flight
AM11
starting at $787
LATAM Chile
We and Sa
starting at $4,798
Comodoro Arturo Merino Benítez Airport (SCL) is Santiago’s main international gateway and typically serves as Chile’s primary hub for full-service carriers and many long-haul flights, while also handling some low-cost operators. It sits about 15–20 km northwest of downtown Santiago; road transfer by taxi or rideshare can take roughly 20–40 minutes depending on traffic, with airport buses and shared shuttles usually offering cheaper options in the 30–90 minute range overall. A suburban metro extension and bus connections provide budget-friendly access, though transfer times vary. Pros: comprehensive facilities, many international connections and frequent airline choices. Cons: can be busy during peak hours and traffic to the city can be unpredictable.
Mexico City’s main gateway is Benito Juárez International Airport (MEX), the country’s primary international hub handling a mix of full-service and low-cost carriers; it typically serves most long-haul and domestic flights. Located about 8–13 km east of the historic center, travel times to downtown can range from 20–60 minutes depending on traffic. Options include the metro (Line 5 and transfer connections) and the newer airport bus and Aerotren links, with fares usually low to moderate, while taxis and rideshares are faster but can cost more. Pros: extensive connections and amenities; cons: can be crowded and subject to traffic delays during peak hours. There are also smaller general-aviation fields and military airbases around the metropolitan area for private or charter operations.
The cheapest flight ticket from Santiago to Mexico City according to data for the last 48 hours costs $266
Often the best time to buy tickets from Santiago to Mexico City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Mexico City can be found flying in these months: June, May, July.
The fastest flights from Santiago to Mexico City start from 11 hours 14 minutes in the air.
The following airlines operate direct flights on the route Santiago — Mexico City: LATAM Chile, Wamos Air, Aeromexico
In different months, ticket prices from Santiago to Mexico City vary: minimum — $340 (June 2026), maximum — $457 (September 2026). Typically, the flight costs $388–$399.
Ticket prices for Santiago — Mexico City follow a predictable curve: rise, peak, and decline. This typical seasonal pattern lets you plan your purchase to avoid overpaying.
Prices rise from June 2026 to September 2026 (+35%), then decline from May 2026 to June 2026 (4%). The cheapest tickets are in May 2026–June 2026 (averaging $347), while the priciest are in July 2026–September 2026 ($428).
For savings, plan your flight for May 2026–June 2026 — you could save up to 19%. Try to avoid July 2026–September 2026 when possible: prices are at their highest then.
Price spread on this route is 11.8%. Costs depend heavily on the season, so flexibility in choosing your departure month is especially valuable here.
We couldn't find any special offers for flights from Santiago to Mexico City