Ryanair
Mo and Fr
starting at $351
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Pisa to Madrid. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Pisa to Madrid, despite the fact that sometimes flights with transfers can cost significantly less.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Ryanair
Mo and Fr
starting at $351
The only airline operating direct flights from Pisa to Madrid is Ryanair. Flights operate on Monday and Friday.
The cost of a one-way flight from Pisa to Madrid ranges from $39 (May 2026) to $99 (August 2026). On average, the ticket price is about $73–$87.
Flight prices from Pisa to Madrid are steadily rising: from May 2026 to August 2026, ticket costs increased by 153%. The sooner you book, the better the deal.
The most significant price increase was from May 2026 to August 2026 — up 153%. The best time to fly is May 2026–June 2026, when the average price is $53. In July 2026–August 2026, tickets cost around $93.
Given the rising prices, it's best not to delay your purchase. Flying in May 2026–June 2026 can save you up to 43% compared to the most expensive months.
Price variation across months on this route is 31%. Your choice of departure month significantly affects the total flight cost.
Pisa — Madrid
08/29/2026
Departure
Direct flight
MW9471
starting at $111
Pisa — Madrid
05/15/2026
Departure
Direct flight
MW9471
starting at $204
starting at $111
starting at $71
Flights from Pisa to Madrid are operated by several airlines — Mokulele Airlines and Ryanair. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $71, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.
The cheapest flight ticket from Pisa to Madrid according to data for the last 48 hours costs $71
Often the best time to buy tickets from Pisa to Madrid is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Pisa to Madrid can be found flying in these months: May, June, July.
The fastest flights from Pisa to Madrid start from 2 hours 20 minutes in the air.
The following airlines operate direct flights on the route Pisa — Madrid: Mokulele Airlines
We couldn't find any special offers for flights from Pisa to Madrid
The cheapest one-way flight from Pisa to Madrid departs on 05/14/2026, is operated by Ryanair and costs $71
The cheapest roundtrip flight from Pisa to Madrid departs on 06/08/2026, is operated by Ryanair and costs $117
Fastest flight from Pisa to Madrid takes 2h 20m
There are direct flights on this route 2 days a week: Fr and Sa
The distance between Pisa and Madrid is 1218km (755 miles). There are 3 direct flights from Pisa to Madrid. Pisa and Madrid are in the same time zone. Flights from Pisa begin at 6:10 AM. The latest flight from Pisa departs at 7:20 PM