Cheap Flights from Panama City to Santo Domingo Starting at $237

Helping travelers to find the best flight offers

Cheapest flights from Panama City to Santo Domingo

Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Panama City to Santo Domingo. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.

Cheapest one way flight

$237

Avianca
Avianca
1 transfer
6h 36m
02/04/2025

The cheapest one-way flight from Panama City to Santo Domingo departs on 02/04/2025, is operated by Avianca and costs $237

Cheapest round trip flight

$444

Avianca
Avianca
1 transfer
19h 5m
01/25/2025

The cheapest roundtrip flight from Panama City to Santo Domingo departs on 01/25/2025, is operated by Avianca and costs $444

The fastest flight

6h 36m

Fastest flight from Panama City to Santo Domingo takes 6h 36m

Direct flights

No direct flights

There are no direct flights on this route.

Earliest flight

7:18 AM

Latest flight

10:13 PM

Direct flights count

35

Distance

1474km

Timezone difference

1h

The distance between Panama City and Santo Domingo is 1474km (914 miles). There are 35 direct flights from Panama City to Santo Domingo. The time difference between Panama City and Santo Domingo is 1h . Flights from Panama City begin at 7:18 AM. The latest flight from Panama City departs at 10:13 PM.

See also:

Cheap flights to Dominican Republic

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Direct flights airfares to Santo Domingo

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Cheapest air tickets to Panama City

Airfare from Panama City to Santo Domingo by month

We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Panama City to Santo Domingo

February 2025
Lowest price
on average:
$256

Airlines operating on route

Below you will find a list of airlines operating flights on the Panama City — Santo Domingo route and the starting prices for flights of each specific airline on it.

Avianca
Avianca

Starting at $246

Direct Flights from Panama City to Santo Domingo

A direct flight is the most convenient and comfortable way to fly from Panama City to Santo Domingo, despite the fact that sometimes flights with transfers can cost significantly less.

Copa Airlines

Panama City — Santo Domingo

PTY — SDQ

01/23/2025

Departure date

Direct flight

CM463

Starting at $561

Copa Airlines

Panama City — Santo Domingo

PTY — SDQ

01/28/2025

Departure date

Direct flight

CM268

Starting at $516

Copa Airlines

Panama City — Santo Domingo

PTY — SDQ

01/29/2025

Departure date

Direct flight

CM268

Starting at $516

Copa Airlines

Panama City — Santo Domingo

PTY — SDQ

01/31/2025

Departure date

Direct flight

CM298

Starting at $569

Copa Airlines

Panama City — Santo Domingo

PTY — SDQ

02/01/2025

Departure date

Direct flight

CM268

Starting at $615

Copa Airlines

Panama City — Santo Domingo

PTY — SDQ

02/04/2025

Departure date

Direct flight

CM463

Starting at $506

Copa Airlines

Panama City — Santo Domingo

PTY — SDQ

02/06/2025

Departure date

Direct flight

CM107

Starting at $553

Copa Airlines

Panama City — Santo Domingo

PTY — SDQ

02/27/2025

Departure date

Direct flight

CM463

Starting at $564

Schedule of direct flights from Panama City to Santo Domingo

A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Panama City to Santo Domingo:

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Unable to find information about the schedule of direct flights from

Panama City airports overview

PTY
Tocumen International Airport
Copa Airlines
Avianca
Airlines flying to this airport
$246
Starting at
$419
on average

Santo Domingo airports overview

SDQ
Las Americas International Airport
Copa Airlines
Avianca
Airlines flying to this airport
$246
Starting at
$419
on average

Frequently asked questions (FAQ)

Answers to questions about the route that travelers are most interested in.

How much is the cheapest flight ticket from Panama City to Santo Domingo?

The cheapest flight ticket from Panama City to Santo Domingo according to data for the last 48 hours costs $237

When is the best time to buy air tickets on the route Panama City — Santo Domingo?

Often the best time to buy tickets from Panama City to Santo Domingo is 2 months before departure.

When is the cheapest time of year to fly from Panama City to Santo Domingo?

Based on statistics over the past years, the lowest prices for flights from Panama City to Santo Domingo can be found flying in these months: February.

How long does it take to fly from Panama City to Santo Domingo?

The fastest flights from Panama City to Santo Domingo start from 6 hours 36 minutes in the air.

Which airline can fly direct from Panama City to Santo Domingo?

The following airlines operate direct flights on the route Panama City — Santo Domingo: Copa Airlines

Special offers and sales on air tickets from Panama City to Santo Domingo

We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.

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We couldn't find any special offers for flights from Panama City to Santo Domingo

Alternative routes

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