Cheap Flights from Medellin to Santo Domingo

Cheapest flights from Medellin to Santo Domingo

Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Medellin to Santo Domingo. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.

Cheapest one way flight

$177

Asian Air

Direct flight

2h 32m

09/22/2026

The cheapest one-way flight from Medellin to Santo Domingo departs on 09/22/2026, is operated by Asian Air and costs $177

Cheapest round trip flight

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There is no information about the cheapest roundtrip flight from Medellin to Santo Domingo

The fastest flight

2h 32m

Fastest flight from Medellin to Santo Domingo takes 2h 32m

Direct flights

Several times a week

There are direct flights on this route 3 days a week: Mo, Tu, and Th

Earliest flight

10:05 AM

Latest flight

8:25 PM

Direct flights count

13

Distance

1493km

Timezone difference

1h

The distance between Medellin and Santo Domingo is 1493km (926 miles). There are 13 direct flights from Medellin to Santo Domingo. The time difference between Medellin and Santo Domingo is 1h. Flights from Medellin begin at 10:05 AM. The latest flight from Medellin departs at 8:25 PM

Remember that on average the ideal time to book flights is 2 months before departure!

Airfare from Medellin to Santo Domingo by month

The minimum one-way ticket price from Medellin to Santo Domingo is $208 (October 2026), while the maximum is $225 (September 2026). On average, a ticket costs $217–$225.

October 2026

Lowest price

on average:

$208

September 2026

Highest price

on average:

$225

Avg Price

Airlines operating on route

The route Medellin — Santo Domingo is served by a single airline — Asian Air. This means that when planning your trip, you won’t need to spend time choosing between dozens of carriers: all flights are operated by one provider, which simplifies the booking process. Despite the limited choice, passengers can still plan ahead, select optimal departure dates, and buy tickets at the lowest price — from $177. Using our service, you can quickly compare available Asian Air flights and book a seat in advance at a favorable rate.

Asian Air

starting at $177

Non-stop flights from Medellin to Santo Domingo

A non-stop flight is the most convenient and comfortable way to fly from Medellin to Santo Domingo, despite the fact that sometimes flights with transfers can cost significantly less.

Medellin — Santo Domingo

MDE — SDQ

09/22/2026

Departure

Direct flight

DM1739

starting at $216

Medellin — Santo Domingo

MDE — SDQ

09/21/2026

Departure

Direct flight

DM1737

starting at $226

Medellin — Santo Domingo

MDE — SDQ

10/22/2026

Departure

Direct flight

DM1737

starting at $208

Medellin — Santo Domingo

MDE — SDQ

10/27/2026

Departure

Direct flight

DM1735

starting at $227

Medellin — Santo Domingo

MDE — SDQ

12/01/2026

Departure

Direct flight

DM1739

starting at $434

Schedule of direct flights from Medellin to Santo Domingo

There are most likely no direct flights on the Medellin — Santo Domingo route

Medellin airports overview

Enrique Olaya Herrera Airport

•

EOH

3km

Small urban airport in Medellín, Colombia, handling mainly domestic and regional flights and general aviation; convenient for access to the city center and nearby neighborhoods.

Jose Maria Cordova International Airport

•

MDE

18km

•

Santo Domingo airports overview

La Isabela International Airport

•

JBQ

9km

Las Americas International Airport

•

SDQ

34km

Serving Santo Domingo, Dominican Republic, handling domestic and international flights with regular connections across the Caribbean and the Americas; convenient for access to the capital and nearby resort areas.

•

Frequently asked questions (FAQ)

Answers to questions about the route that travelers are most interested in.

What is the cheapest price for flights from Medellin to Santo Domingo?

The cheapest flight ticket from Medellin to Santo Domingo according to data for the last 48 hours costs $177

When is the best time to buy air tickets on the route Medellin — Santo Domingo?

Often the best time to buy tickets from Medellin to Santo Domingo is 2 months before departure.

When is the cheapest time of year to fly from Medellin to Santo Domingo?

Based on statistics over the past years, the lowest prices for flights from Medellin to Santo Domingo can be found flying in these months: October, September.

How long does it take to fly from Medellin to Santo Domingo?

The fastest flights from Medellin to Santo Domingo start from 2 hours 32 minutes in the air.

Which airline can fly direct from Medellin to Santo Domingo?

The following airlines operate direct flights on the route Medellin — Santo Domingo: Asian Air

Special offers and sales on air tickets from Medellin to Santo Domingo

We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.

We couldn't find any special offers for flights from Medellin to Santo Domingo

Alternative routes

Apartado ➜ Santo Domingo•Armenia ➜ Santo Domingo•Bucaramanga ➜ Santo Domingo•Bogota ➜ Santo Domingo•Cartago ➜ Santo Domingo•Barrancabermeja ➜ Santo Domingo•Ibague ➜ Santo Domingo•Manizales ➜ Santo Domingo•Pereira ➜ Santo Domingo•Quibdo ➜ Santo Domingo•Medellin ➜ Cap Haitien•Medellin ➜ Les Cayes•Medellin ➜ Guantanamo•Medellin ➜ La Romana•Medellin ➜ Port Au Prince•Medellin ➜ Puerto Plata•Medellin ➜ Ponce•Medellin ➜ San Juan•Medellin ➜ Santiago

•••••••••••••••••••

Cheapest one way flight

$177

Asian Air

Direct flight

2h 32m

09/22/2026

The cheapest one-way flight from Medellin to Santo Domingo departs on 09/22/2026, is operated by Asian Air and costs $177

Cheapest round trip flight

—

There is no information about the cheapest roundtrip flight from Medellin to Santo Domingo

The fastest flight