Asian Air
Su, Mo, Tu, We, Fr, and Sa
starting at $222
Aerorepublica
Tu, Th, and Sa
starting at $218
Compare airlines, prices, and flight durations for your trip
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Medellin to Santo Domingo. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Medellin to Santo Domingo, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Medellin to Santo Domingo:
•
•
•
•
•
•
Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Asian Air
Su, Mo, Tu, We, Fr, and Sa
starting at $222
Aerorepublica
Tu, Th, and Sa
starting at $218
Medellin — Santo Domingo
03/26/2026
Departure
Direct flight
DM1697
starting at $207
starting at $207
starting at $153
The route Medellin — Santo Domingo is served by several airlines: Asian Air and Aerorepublica. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $153 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.
The cheapest one-way flight from Medellin to Santo Domingo departs on 03/26/2026, is operated by Aerorepublica and costs $153
There is no information about the cheapest roundtrip flight from Medellin to Santo Domingo
Fastest flight from Medellin to Santo Domingo takes 2h 33m
There are direct flights on this route 1 day a week: Th
The distance between Medellin and Santo Domingo is 1492km (925 miles). The average flight duration is 2h 32m. There are 19 direct flights from Medellin to Santo Domingo. The time difference between Medellin and Santo Domingo is 1h. Flights from Medellin begin at 10:05 AM. The latest flight from Medellin departs at 9:27 PM
The cheapest flight ticket from Medellin to Santo Domingo according to data for the last 48 hours costs $153
Often the best time to buy tickets from Medellin to Santo Domingo is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Medellin to Santo Domingo can be found flying in these months: April.
The fastest flights from Medellin to Santo Domingo start from 2 hours 33 minutes in the air.
The following airlines operate direct flights on the route Medellin — Santo Domingo: Asian Air
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Medellin to Santo Domingo
We couldn't find any special offers for flights from Medellin to Santo Domingo