Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Panama City to Mexico City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Panama City to Mexico City, despite the fact that sometimes flights with transfers can cost significantly less.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
There are most likely no direct flights on the Panama City — Mexico City route
Tocumen International Airport (PTY) is Panama City’s main international hub, handling most long-haul and connecting flights and serving carriers from legacy network airlines to regional and low-cost operators. Located about 24 km (15 miles) northeast of downtown, it’s typically reached by taxi, ride-share or airport shuttle in roughly 25–40 minutes depending on traffic; fares can vary but are usually comparable to other Latin American capitals. PTY offers a wide range of passenger services and connections, making it convenient for transfers, though peak-time crowds and occasional delays can affect comfort. Public buses and private transfers are cheaper alternatives but are slightly slower. Albrook “Marcos A. Gelabert” International Airport (PAC) functions mainly as Panama City’s domestic and regional airport, often used by local carriers and short-haul budget airlines. Situated roughly 3–4 km (about 2 miles) from the city center near the Albrook district, it’s typically a 10–15 minute taxi or ride-share trip and can be reached by city buses for a very low fare. PAC can be a good option for quick regional hops and lower-cost domestic travel, though facilities are smaller and flight options fewer than at Tocumen; security queues and limited international services are occasional drawbacks.
Mexico City is served mainly by Benito Juárez International (MEX), the country's primary international hub that handles a mix of full-service carriers and growing low-cost airlines; a new Felipe Ángeles Airport (NLU) north of the city is increasingly used for budget and domestic connections. Benito Juárez sits about 5–10 km east of downtown, typically reachable by taxi or ride-hailing in 20–40 minutes depending on traffic, and by metro/Metrobus in around 35–60 minutes with fares usually low-cost. Felipe Ángeles is roughly 40–50 km from the center, often taking 45–90 minutes by road; shuttle and bus services are available at modest fares. Pros: MEX offers extensive international connections and public transit links; NLU can be cheaper and less congested. Cons: both airports can face heavy traffic and longer transfer times, and services at peripheral terminals may be more basic.
The minimum one-way ticket price from Panama City to Mexico City is $183 (June 2026), while the maximum is $275 (November 2026). On average, a ticket costs $229–$275.
Panama City — Mexico City
09/10/2026
Departure
Direct flight
AM465
starting at $597
Panama City — Mexico City
06/29/2026
Departure
Direct flight
CM120
starting at $626
Panama City — Mexico City
06/22/2026
Departure
Direct flight
AM465
starting at $556
The route Panama City — Mexico City is served by several airlines: Aeromexico, Copa Airlines, and Avianca. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $205 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.
The cheapest flight ticket from Panama City to Mexico City according to data for the last 48 hours costs $205
Often the best time to buy tickets from Panama City to Mexico City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Panama City to Mexico City can be found flying in these months: June, November.
The fastest flights from Panama City to Mexico City start from 8 hours 45 minutes in the air.
The following airlines operate direct flights on the route Panama City — Mexico City: Aeromexico, Copa Airlines
We couldn't find any special offers for flights from Panama City to Mexico City
The cheapest one-way flight from Panama City to Mexico City departs on 06/22/2026, is operated by Avianca and costs $205
The cheapest roundtrip flight from Panama City to Mexico City departs on 07/15/2026, is operated by Aeromexico and costs $411
Fastest flight from Panama City to Mexico City takes 8h 45m
There are direct flights on this route 2 days a week: Mo and Th
The distance between Panama City and Mexico City is 2407km (1492 miles). There are 39 direct flights from Panama City to Mexico City. The time difference between Panama City and Mexico City is 1h. Flights from Panama City begin at 9:19 AM. The latest flight from Panama City departs at 10:11 PM