Compare airlines, prices, and flight durations for your trip
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Medellin to Mexico City:
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Answers to questions about the route that travelers are most interested in.
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Fly from Medellín to Mexico City with confidence — our search scans over 700 airlines, 50+ agencies, and more than 5 top booking systems to find the best prices, schedules, and flexible conditions for your trip. Friendly, fast and thorough, we make it easy to compare nonstop and connecting options so you can book the flight that fits your plans and budget.
Unable to find information about the schedule of direct flights from
Medellin — Mexico City
04/20/2026
Departure
Direct flight
0O234
starting at $406
Medellin — Mexico City
04/27/2026
Departure
Direct flight
AM799
starting at $440
Medellin — Mexico City
04/30/2026
Departure
Direct flight
AM799
starting at $486
Medellin — Mexico City
09/10/2026
Departure
Direct flight
0O234
starting at $321
Medellin — Mexico City
10/30/2026
Departure
Direct flight
AM799
starting at $560
starting at $321
starting at $440
starting at $247
starting at $250
starting at $269
starting at $291
starting at $291
The Medellin — Mexico City route is served by a wide range of airlines: 7 in total, including Air Ocean, Aeromexico, C.A.I. Second, Southern Air, Avianca, Asian Air, and B&H Airlines. Competition among carriers gives passengers the opportunity to find tickets at attractive fares — with prices starting from $247. Our service helps compare all available offers within seconds and choose the most convenient option. You can filter flights by price, departure time, or baggage rules to make your trip as comfortable as possible. With so many airlines, there’s always a chance to catch special promotions and save.
Medellín is served by two main airports with different roles. José María Córdova (MDE) is the international hub located in Rionegro, typically handling most long-haul and full-service carriers; it sits about 35–45 km from downtown Medellín (roughly 45–60 minutes by car depending on traffic). Ground transport options usually include airport shuttles, taxis and app-based rides (fares commonly range from moderate to higher than city taxis), plus occasional private transfer services — public buses are available but slower. Olaya Herrera (EOH) is a smaller domestic airport much closer to the city center (around 5–10 minutes by car), primarily serving regional and budget flights; it can be convenient for quick domestic connections though facilities may be more basic. Pros: MDE offers broader international connections and fuller amenities; EOH provides unbeatable proximity and faster access to central neighborhoods. Cons: MDE’s distance can add time and cost, while EOH’s limited international service and smaller terminals may feel cramped.
Fly non-stop from Medellín to Mexico City for the quickest, most convenient way to connect Colombia’s vibrant culture with Mexico’s bustling capital — perfect for business or a short getaway. While connecting options can sometimes be cheaper, a direct flight saves you hours, reduces hassle and keeps your trip more comfortable, so book now to maximize time on the ground.
Mexico City is served primarily by Benito Juárez International (MEX), the country’s main international hub, and Felipe Ángeles International (NLU), a newer facility handling growing domestic and some international services. MEX typically hosts full-service and low-cost carriers alike — think Aeroméxico and several budget airlines — while NLU can be more budget- and domestic-oriented depending on schedules. Benito Juárez sits about 10–15 km east of the historic center, reachable by metro/light rail in roughly 30–50 minutes for low fares or by taxi/ride-hail in 20–40 minutes with variable fares; Felipe Ángeles is farther north, often taking 45–75 minutes by road. Pros: MEX offers extensive connections and frequent public-transit links; NLU can be less crowded and may offer cheaper options for domestic flyers. Cons: both can be affected by heavy traffic to/from the city and peak-hour congestion at terminals.
The cheapest flight ticket from Medellin to Mexico City according to data for the last 48 hours costs $247
Often the best time to buy tickets from Medellin to Mexico City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Medellin to Mexico City can be found flying in these months: April, October, September.
The fastest flights from Medellin to Mexico City start from 13 hours 34 minutes in the air.
The following airlines operate direct flights on the route Medellin — Mexico City: Air Ocean, Aeromexico
The minimum one-way ticket price from Medellin to Mexico City is $247 (April 2026), while the maximum is $291 (September 2026). On average, a ticket costs $276–$582.
The cheapest one-way flight from Medellin to Mexico City departs on 04/30/2026, is operated by C.A.I. Second and costs $247
The cheapest roundtrip flight from Medellin to Mexico City departs on 04/17/2026, is operated by Asian Air and costs $422
Fastest flight from Medellin to Mexico City takes 13h 34m
There are direct flights on this route 3 days a week: Mo, Th, and Fr
The distance between Medellin and Mexico City is 2938km (1822 miles). There are 23 direct flights from Medellin to Mexico City. The time difference between Medellin and Mexico City is 1h. Flights from Medellin begin at 10:35 PM. The latest flight from Medellin departs at 12:45 AM
We couldn't find any special offers for flights from Medellin to Mexico City