starting at $211
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starting at $369
starting at $414
starting at $431
starting at $433
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Mexico City to Panama City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
In different months, ticket prices from Mexico City to Panama City vary: minimum — $265 (September 2026), maximum — $307 (July 2027). Typically, the flight costs $286–$307.
A non-stop flight is the most convenient and comfortable way to fly from Mexico City to Panama City, despite the fact that sometimes flights with transfers can cost significantly less.
All airlines serving Mexico City — Panama City operate daily direct flights: Copa Airlines and Aeromexico fly every day.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Flight prices from Mexico City to Panama City barely change from month to month. You can comfortably choose any convenient dates — there won't be a significant overpayment.
There is a slight difference: it's a bit cheaper in September 2026–November 2026 (averaging $266) and slightly more in April 2027–July 2027 ($307). But overall, the difference is small.
On this route, you don't need to target specific months — prices are stable. The difference between the cheapest and most expensive period is only 13%. Book whenever it's convenient.
Monthly price variation is just 7.2%. Ticket costs on this route are among the most predictable.
The route Mexico City — Panama City is served by many carriers — 6 in total, including Copa Airlines, Aeromexico, VivaAerobus, Skytrans Airlines, Volaris, and Avianca. This gives passengers wide opportunities: from finding the lowest fare (from $211) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.
starting at $211
starting at $218
starting at $369
starting at $414
starting at $431
starting at $433
Mexico City — Panama City
10/24/2026
Departure
Direct flight
CM121
starting at $211
Mexico City — Panama City
10/27/2026
Departure
Direct flight
AM464
starting at $218
Mexico City — Panama City
11/09/2026
Departure
Direct flight
AM464
starting at $223
Mexico City — Panama City
11/07/2026
Departure
Direct flight
AM464
starting at $226
Mexico City — Panama City
10/16/2026
Departure
Direct flight
CM135
starting at $231
Mexico City — Panama City
11/08/2026
Departure
Direct flight
AM464
starting at $237
Mexico City — Panama City
10/10/2026
Departure
Direct flight
CM121
starting at $251
Mexico City — Panama City
12/15/2026
Departure
Direct flight
AM464
starting at $258
Mexico City — Panama City
12/09/2026
Departure
Direct flight
AM464
starting at $259
Mexico City — Panama City
10/14/2026
Departure
Direct flight
AM464
starting at $260
Copa Airlines
Every day
starting at $178
Aeromexico
Every day
starting at $172
The cheapest flight ticket from Mexico City to Panama City according to data for the last 48 hours costs $211
Often the best time to buy tickets from Mexico City to Panama City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Mexico City to Panama City can be found flying in these months: September, November, April.
The fastest flights from Mexico City to Panama City start from 3 hours 41 minutes in the air.
The following airlines operate direct flights on the route Mexico City — Panama City: Copa Airlines, Aeromexico
The cheapest one-way flight from Mexico City to Panama City departs on 10/24/2026, is operated by Copa Airlines and costs $211
The cheapest roundtrip flight from Mexico City to Panama City departs on 01/18/2027, is operated by Aeromexico and costs $356
Fastest flight from Mexico City to Panama City takes
All airports
There are direct flights on this route 6 days a week: Su, Mo, Tu, We, Fr, and Sa
The distance between Mexico City and Panama City is 2407km (1492 miles). The average flight duration is 4h. There are 55 direct flights from Mexico City to Panama City. The time difference between Mexico City and Panama City is 1h. Flights from Mexico City begin at 5:50 AM. The latest flight from Mexico City departs at 2:10 AM
We couldn't find any special offers for flights from Mexico City to Panama City