Schedule of direct flights from Mexico City to Panama City
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Mexico City to Panama City:
Mexico City airports overview
Panama City airports overview
Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Mexico City to Panama City
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Alternative routes
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Cheapest one way flight
$184
VivaAerobus
2 transfers
15h 15m
02/25/2025
The cheapest one-way flight from Mexico City to Panama City departs on 02/25/2025, is operated by VivaAerobus and costs $184
Cheapest round trip flight
$476
Avianca
1 transfer
16h 35m
05/31/2025
The cheapest roundtrip flight from Mexico City to Panama City departs on 05/31/2025, is operated by Avianca and costs $476
The fastest flight
8h 40m
Fastest flight from Mexico City to Panama City takes 8h 40m
Direct flights
No direct flights
There are no direct flights on this route.
Earliest flight
5:55 AM
Latest flight
2:00 AM
Direct flights count
51
Distance
2407km
Timezone difference
1h
The distance between Mexico City and Panama City is 2407km (1492 miles).There are 51 direct flights from Mexico City to Panama City.The time difference between Mexico City and Panama City is 1h .Flights from Mexico City begin at 5:55 AM.The latest flight from Mexico City departs at 2:00 AM.
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Mexico City to Panama City
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Mexico City to Panama City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
Unable to find information about the schedule of direct flights from
Below you will find a list of airlines operating flights on the Mexico City — Panama City route and the starting prices for flights of each specific airline on it.
A direct flight is the most convenient and comfortable way to fly from Mexico City to Panama City, despite the fact that sometimes flights with transfers can cost significantly less.
Mexico City — Panama City
March 4
Avianca
$236
February 2025
Lowest price
on average:
$243
October 2025
Highest price
on average:
$383
How much is the cheapest flight ticket from Mexico City to Panama City?
The cheapest flight ticket from Mexico City to Panama City according to data for the last 48 hours costs $184
When is the best time to buy air tickets on the route Mexico City — Panama City?
Often the best time to buy tickets from Mexico City to Panama City is 2 months before departure.
When is the cheapest time of year to fly from Mexico City to Panama City?
Based on statistics over the past years, the lowest prices for flights from Mexico City to Panama City can be found flying in these months: February, July, October.
How long does it take to fly from Mexico City to Panama City?
The fastest flights from Mexico City to Panama City start from 8 hours 40 minutes in the air.
Which airline can fly direct from Mexico City to Panama City?
The following airlines operate direct flights on the route Mexico City — Panama City: Copa Airlines
