Unfortunately, we were unable to find any airports in Knoxville. We'll try to look better another time
Helping travelers to find the best flight offers
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Knoxville to Chicago:
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Unfortunately, we were unable to find any airports in Knoxville. We'll try to look better another time
Unfortunately, we were unable to find any airports in Chicago. We'll try to look better another time
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Knoxville to Chicago. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
Below you will find a list of airlines operating flights on the Knoxville — Chicago route and the starting prices for flights of each specific airline on it.
A direct flight is the most convenient and comfortable way to fly from Knoxville to Chicago, despite the fact that sometimes flights with transfers can cost significantly less.
We tried looking for a list of airlines flying on Knoxville to Chicago route and that list simply appears to be empty
Unable to find information about the schedule of direct flights from
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Knoxville to Chicago
We couldn't find any special offers for flights from Knoxville to Chicago
Knoxville — Chicago
04/08/2025
Departure date
Direct flight
AA5748
Starting at $445
Knoxville — Chicago
04/08/2025
Departure date
Direct flight
AA5742
Starting at $439
Knoxville — Chicago
01/12/2026
Departure date
Direct flight
UA4680
Starting at $318
The cheapest flight ticket from Knoxville to Chicago according to data for the last 48 hours costs $269
Often the best time to buy tickets from Knoxville to Chicago is 2 months before departure.
The fastest flights from Knoxville to Chicago start from 21 hours 59 minutes in the air.
The following airlines operate direct flights on the route Knoxville — Chicago: American Airlines, United Airlines
The cheapest one-way flight from Knoxville to Chicago departs on 04/07/2025, is operated by Allegiant Air and costs $269
There is no information about the cheapest roundtrip flight from Knoxville to Chicago
Fastest flight from Knoxville to Chicago takes 21h 59m
There are no direct flights on this route.
The distance between Knoxville and Chicago is 744km (461 miles). There are 40 direct flights from Knoxville to Chicago. The time difference between Knoxville and Chicago is 1h . Flights from Knoxville begin at 6:20 AM. The latest flight from Knoxville departs at 6:51 PM.