There are most likely no direct flights on the Iquique — Santiago route
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A non-stop flight is the most convenient and comfortable way to fly from Iquique to Santiago, despite the fact that sometimes flights with transfers can cost significantly less.
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There are most likely no direct flights on the Iquique — Santiago route
Iquique — Santiago
12/18/2026
Departure
Direct flight
H2321
starting at $56
starting at $56
The route Iquique — Santiago is served by a single airline — Sky Airline. This means that when planning your trip, you won’t need to spend time choosing between dozens of carriers: all flights are operated by one provider, which simplifies the booking process. Despite the limited choice, passengers can still plan ahead, select optimal departure dates, and buy tickets at the lowest price — from $56. Using our service, you can quickly compare available Sky Airline flights and book a seat in advance at a favorable rate.
The cheapest one-way flight from Iquique to Santiago departs on 09/15/2026, is operated by Sky Airline and costs $60
There is no information about the cheapest roundtrip flight from Iquique to Santiago
Fastest flight from Iquique to Santiago takes 2h 14m
There are direct flights on this route 1 day a week: Fr
The distance between Iquique and Santiago is 1470km (911 miles). There are 92 direct flights from Iquique to Santiago. Iquique and Santiago are in the same time zone. Flights from Iquique begin at 7:03 AM. The latest flight from Iquique departs at 1:57 AM
The cheapest flight ticket from Iquique to Santiago according to data for the last 48 hours costs $60
Often the best time to buy tickets from Iquique to Santiago is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Iquique to Santiago can be found flying in these months: December, September.
The fastest flights from Iquique to Santiago start from 2 hours 14 minutes in the air.
The following airlines operate direct flights on the route Iquique — Santiago: Sky Airline
The minimum one-way ticket price from Iquique to Santiago is $41 (December 2026), while the maximum is $45 (September 2026). On average, a ticket costs $43–$45.
We couldn't find any special offers for flights from Iquique to Santiago