Cheap Flights from Antofagasta to Santiago — $121

On the Antofagasta — Santiago route, flights are operated only by LATAM Chile. This simplifies the choice for passengers, as all tickets come from a single trusted carrier. Our service lets you instantly check fares for upcoming dates and find the most advantageous option. The minimum ticket price starts at $121, making this trip affordable for a wide range of travelers. To save even more, we recommend booking early and keeping an eye on promotions — LATAM Chile regularly offers special deals.

Fly from Antofagasta to Santiago with confidence—our search scans over 700 airlines, 50+ travel agencies and more than 5 top booking systems to surface the best fares, schedules and ticket conditions for your trip. Quick, clear comparisons help you pick the ideal flight so you can relax knowing you got the best deal and timing for your journey to Chile’s capital.

Comodoro Arturo Merino Benítez (Andrés Sabella) — Antofagasta's main airport is a medium-sized regional gateway handling domestic flights and a few international connections, often serving full-service carriers and local budget airlines alike. Located about 10–15 km north of the city center, it can be reached in roughly 15–30 minutes by taxi or shuttle; buses and ride-hailing services are also available with fares typically lower than private transfers. Travelers can expect a straightforward, functional terminal with basic amenities—convenient for quick connections but not as large as major international hubs. Pros: close to town and efficient for domestic travel; cons: limited long-haul options and fewer lounge or dining choices compared with larger airports.

Fly direct from Antofagasta to Santiago for the quickest, most convenient way to get between Chile’s north and capital — fewer hassles and more time for what matters. While connecting routes can sometimes be cheaper, a non-stop flight saves hours and offers a more comfortable, stress-free journey; book now to lock in convenience.

We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Antofagasta to Santiago

Santiago’s main air gateway is Comodoro Arturo Merino Benítez International Airport (SCL), the country’s primary international hub handling most long-haul and regional flights and serving carriers like LATAM, Sky Airline and JetSMART. It sits about 16 km northwest of downtown Santiago, with travel times typically around 20–40 minutes by taxi or ride-hail depending on traffic, and roughly 30–45 minutes by the airport express bus (fare ranges commonly fall in the low-to-mid single-digit USD equivalent). SCL offers a full range of passenger services and lounges but can be busy at peak times; public transport is affordable but may feel less convenient for luggage. For budget travellers, some low-cost carriers operate out of secondary terminals within the same complex, which can mean simpler facilities and sometimes lower fares.