Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Antofagasta to Santiago. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
The cost of a one-way flight from Antofagasta to Santiago ranges from $29 (October 2026) to $99 (September 2026). On average, the ticket price is about $64–$99.
A non-stop flight is the most convenient and comfortable way to fly from Antofagasta to Santiago, despite the fact that sometimes flights with transfers can cost significantly less.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Flights from Antofagasta to Santiago are operated by several airlines — Sky Airline, LATAM Chile, and B&H Airlines. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $26, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.
Antofagasta — Santiago
11/20/2026
Departure
Direct flight
H21297
starting at $66
Antofagasta — Santiago
10/24/2026
Departure
Direct flight
LA121
starting at $97
Antofagasta — Santiago
10/31/2026
Departure
Direct flight
JA53
starting at $187
Antofagasta — Santiago
11/20/2026
Departure
Direct flight
LA349
starting at $55
Antofagasta — Santiago
11/10/2026
Departure
Direct flight
LA363
starting at $132
Antofagasta — Santiago
01/18/2027
Departure
Direct flight
LA345
starting at $122
There are most likely no direct flights on the Antofagasta — Santiago route
The cheapest flight ticket from Antofagasta to Santiago according to data for the last 48 hours costs $26
Often the best time to buy tickets from Antofagasta to Santiago is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Antofagasta to Santiago can be found flying in these months: October, September.
The fastest flights from Antofagasta to Santiago start from 1 hour 52 minutes in the air.
The following airlines operate direct flights on the route Antofagasta — Santiago: Sky Airline, LATAM Chile, B&H Airlines
The cheapest one-way flight from Antofagasta to Santiago departs on 11/10/2026, is operated by Sky Airline and costs $26
There is no information about the cheapest roundtrip flight from Antofagasta to Santiago
Fastest flight from Antofagasta to Santiago takes 1h 52m
All airports
There are direct flights on this route 4 days a week: Mo, Tu, Fr, and Sa
The distance between Antofagasta and Santiago is 1089km (675 miles). The average flight duration is 1h 57m. There are 145 direct flights from Antofagasta to Santiago. Antofagasta and Santiago are in the same time zone. Flights from Antofagasta begin at 7:12 AM. The latest flight from Antofagasta departs at 2:00 AM
We couldn't find any special offers for flights from Antofagasta to Santiago