Cheap Flights from La Serena to Santiago

Cheapest flights from La Serena to Santiago

Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from La Serena to Santiago. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.

Cheapest one way flight

$24

Sky Airline

Direct flight

1h 1m

09/26/2026

The cheapest one-way flight from La Serena to Santiago departs on 09/26/2026, is operated by Sky Airline and costs $24

Cheapest round trip flight

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There is no information about the cheapest roundtrip flight from La Serena to Santiago

The fastest flight

1 hour

Fastest flight from La Serena to Santiago takes 1 hour

Direct flights

Several times a week

There are direct flights on this route 2 days a week: Su and Sa

Earliest flight

7:51 AM

Latest flight

11:33 PM

Direct flights count

69

Distance

398km

Timezone difference

0h

The distance between La Serena and Santiago is 398km (247 miles). There are 69 direct flights from La Serena to Santiago. La Serena and Santiago are in the same time zone. Flights from La Serena begin at 7:51 AM. The latest flight from La Serena departs at 11:33 PM

Remember that on average the ideal time to book flights is 2 months before departure!

Airfare from La Serena to Santiago by month

We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from La Serena to Santiago

September 2026

Lowest price

on average:

$29

Avg Price

Airlines operating on route

Flights from La Serena to Santiago are operated by several airlines — LATAM Chile, Sky Airline, and B&H Airlines. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $24, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.

LATAM Chile

starting at $41

Sky Airline

starting at $24

B&H Airlines

starting at $35

Non-stop flights from La Serena to Santiago

A non-stop flight is the most convenient and comfortable way to fly from La Serena to Santiago, despite the fact that sometimes flights with transfers can cost significantly less.

La Serena — Santiago

LSC — SCL

09/26/2026

Departure

Direct flight

LA103

starting at $83

La Serena — Santiago

LSC — SCL

09/27/2026

Departure

Direct flight

LA105

starting at $41

Schedule of direct flights from La Serena to Santiago

There are most likely no direct flights on the La Serena — Santiago route

La Serena airports overview

La Florida Airport

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LSC

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Santiago airports overview

Arturo Merino Benitez Airport

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SCL

23km

Santiago’s main international gateway serving Chile’s capital, offering domestic and international routes and connections across the country. Accessible to downtown by bus, taxi and highway links.

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Frequently asked questions (FAQ)

Answers to questions about the route that travelers are most interested in.

What is the cheapest price for flights from La Serena to Santiago?

The cheapest flight ticket from La Serena to Santiago according to data for the last 48 hours costs $24

When is the best time to buy air tickets on the route La Serena — Santiago?

Often the best time to buy tickets from La Serena to Santiago is 2 months before departure.

When is the cheapest time of year to fly from La Serena to Santiago?

Based on statistics over the past years, the lowest prices for flights from La Serena to Santiago can be found flying in these months: September.

How long does it take to fly from La Serena to Santiago?

The fastest flights from La Serena to Santiago start from 1 hour in the air.

Which airline can fly direct from La Serena to Santiago?

The following airlines operate direct flights on the route La Serena — Santiago: LATAM Chile

Special offers and sales on air tickets from La Serena to Santiago

We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.

We couldn't find any special offers for flights from La Serena to Santiago

Alternative routes

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Cheapest one way flight

$24

Sky Airline

Direct flight

1h 1m

09/26/2026

The cheapest one-way flight from La Serena to Santiago departs on 09/26/2026, is operated by Sky Airline and costs $24

Cheapest round trip flight

—

There is no information about the cheapest roundtrip flight from La Serena to Santiago

The fastest flight