Airlines operating on route
Below you will find a list of airlines operating flights on the La Serena — Santiago route and the starting prices for flights of each specific airline on it.
Starting at $23
Starting at $37
Helping travelers to find the best flight offers
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from La Serena to Santiago. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from La Serena to Santiago
Below you will find a list of airlines operating flights on the La Serena — Santiago route and the starting prices for flights of each specific airline on it.
Starting at $23
Starting at $37
A direct flight is the most convenient and comfortable way to fly from La Serena to Santiago, despite the fact that sometimes flights with transfers can cost significantly less.
La Serena — Santiago
11/14/2025
Departure date
Direct flight
H21713
Starting at $13
La Serena — Santiago
01/14/2026
Departure date
Direct flight
LA101
Starting at $78
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from La Serena to Santiago:
Unable to find information about the schedule of direct flights from
The cheapest flight ticket from La Serena to Santiago according to data for the last 48 hours costs $13
Often the best time to buy tickets from La Serena to Santiago is 2 months before departure.
The fastest flights from La Serena to Santiago start from 1 hour 4 minutes in the air.
The following airlines operate direct flights on the route La Serena — Santiago: Sky Airline, LATAM Chile
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
We couldn't find any special offers for flights from La Serena to Santiago
The cheapest one-way flight from La Serena to Santiago departs on 11/14/2025, is operated by Sky Airline and costs $13
There is no information about the cheapest roundtrip flight from La Serena to Santiago
Fastest flight from La Serena to Santiago takes 1h 4m
There are direct flights on this route 2 days a week: Th and Fr
The distance between La Serena and Santiago is 393km (244 miles). There are 57 direct flights from La Serena to Santiago. La Serena and Santiago are in the same time zone. Flights from La Serena begin at 9:35 AM. The latest flight from La Serena departs at 10:25 PM.
