LATAM Chile
Su, Mo, Tu, and Sa
starting at $155
Compare airlines, prices, and flight durations for your trip
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Cuzco to Santiago. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Cuzco to Santiago, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Cuzco to Santiago:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
LATAM Chile
Su, Mo, Tu, and Sa
starting at $155
The cost of a one-way flight from Cuzco to Santiago ranges from $135 (January 2027) to $260 (March 2026). On average, the ticket price is about $198–$260.
We couldn't find any special offers for flights from Cuzco to Santiago
Cuzco — Santiago
04/21/2026
Departure
Direct flight
LA2366
starting at $304
Cuzco — Santiago
04/26/2026
Departure
Direct flight
LA2466
starting at $286
Cuzco — Santiago
05/03/2026
Departure
Direct flight
LA2466
starting at $221
Cuzco — Santiago
05/05/2026
Departure
Direct flight
LA2366
starting at $304
Cuzco — Santiago
05/06/2026
Departure
Direct flight
LA2366
starting at $186
Cuzco — Santiago
05/24/2026
Departure
Direct flight
LA2366
starting at $476
Cuzco — Santiago
05/25/2026
Departure
Direct flight
LA2366
starting at $402
Cuzco — Santiago
01/22/2027
Departure
Direct flight
LA2366
starting at $186
Cuzco — Santiago
03/27/2026
Departure
Direct flight
LA2366
starting at $184
Cuzco — Santiago
05/08/2026
Departure
Direct flight
LA2366
starting at $277
Flights from Cuzco to Santiago are operated by several airlines — LATAM Chile, B&H Airlines, and Sky Airline. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $132, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.
The cheapest flight ticket from Cuzco to Santiago according to data for the last 48 hours costs $132
Often the best time to buy tickets from Cuzco to Santiago is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Cuzco to Santiago can be found flying in these months: January, March.
The fastest flights from Cuzco to Santiago start from 2 hours 20 minutes in the air.
The following airlines operate direct flights on the route Cuzco — Santiago: LATAM Chile
The cheapest one-way flight from Cuzco to Santiago departs on 05/06/2026, is operated by B&H Airlines and costs $132
There is no information about the cheapest roundtrip flight from Cuzco to Santiago
Fastest flight from Cuzco to Santiago takes 2h 20m
There are direct flights on this route 5 days a week: Su, Mo, Tu, We, and Fr
The distance between Cuzco and Santiago is 2214km (1373 miles). The average flight duration is 3h 15m. There are 5 direct flights from Cuzco to Santiago. The time difference between Cuzco and Santiago is 1h. Flights from Cuzco begin at 9:30 AM. The latest flight from Cuzco departs at 9:30 AM
