Cheap Flights from Amsterdam to Panama City — $478

Amsterdam Schiphol Airport (AMS) is the Netherlands’ main international hub, handling a mix of full-service carriers—most notably KLM and its partners—and a growing number of low-cost airlines. Located about 17 km southwest of the city center, Schiphol is well connected by frequent trains (15–20 minutes) and regional buses; taxi or rideshare transfers typically take 20–40 minutes depending on traffic. Train fares to Amsterdam Centraal are usually moderate and can be lower with prebooked tickets, while buses and shuttles offer budget-friendly options. Pros: extensive connections, plentiful facilities and efficient public transport; cons: can be busy at peak times and walking distances between facilities may be long.

The minimum one-way ticket price from Amsterdam to Panama City is $468 (March 2026), while the maximum is $631 (February 2026). On average, a ticket costs $568–$1,235.

Fly nonstop from Amsterdam to Panama City for the fastest, most convenient way to bridge Europe and Central America — fewer delays, no long layovers, and more time to enjoy Panama’s vibrant culture. While connecting options can sometimes be cheaper, a direct flight saves hours and reduces travel stress, making it the smarter choice for a smoother trip.

Tocumen International (PTY) is Panama City’s main international gateway and a regional hub for connecting flights, frequently served by full-service carriers and major Latin American airlines; it can be pricier than secondary airports but usually offers the widest route choice. The airport sits about 24 km (15 miles) east of downtown; transit options include the Metro Line 2 (around 30–40 minutes), taxis and app rides (25–40 minutes, fares typically varying by provider and time of day), and airport shuttles. Pros: extensive amenities and good connectivity for international itineraries. Cons: busy peak periods and longer transfers to central neighborhoods compared with smaller field options.

The route Amsterdam — Panama City is served by several airlines: KLM, Air Europa, and Vueling. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $478 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.