There are most likely no direct flights on the Santo Domingo — Guatemala City route
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santo Domingo to Guatemala City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
The minimum one-way ticket price from Santo Domingo to Guatemala City is $132 (September 2026), while the maximum is $303 (August 2026). On average, a ticket costs $218–$303.
A non-stop flight is the most convenient and comfortable way to fly from Santo Domingo to Guatemala City, despite the fact that sometimes flights with transfers can cost significantly less.
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There are most likely no direct flights on the Santo Domingo — Guatemala City route
Santo Domingo — Guatemala City
09/12/2026
Departure
Direct flight
DM4602
starting at $174
starting at $132
The route Santo Domingo — Guatemala City is served by a single airline — Asian Air. This means that when planning your trip, you won’t need to spend time choosing between dozens of carriers: all flights are operated by one provider, which simplifies the booking process. Despite the limited choice, passengers can still plan ahead, select optimal departure dates, and buy tickets at the lowest price — from $132. Using our service, you can quickly compare available Asian Air flights and book a seat in advance at a favorable rate.
The cheapest flight ticket from Santo Domingo to Guatemala City according to data for the last 48 hours costs $132
Often the best time to buy tickets from Santo Domingo to Guatemala City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santo Domingo to Guatemala City can be found flying in these months: September, August.
The fastest flights from Santo Domingo to Guatemala City start from 3 hours 30 minutes in the air.
The following airlines operate direct flights on the route Santo Domingo — Guatemala City: Asian Air
The cheapest one-way flight from Santo Domingo to Guatemala City departs on 09/12/2026, is operated by Asian Air and costs $132
The cheapest roundtrip flight from Santo Domingo to Guatemala City departs on 09/24/2026, is operated by Asian Air and costs $285
Fastest flight from Santo Domingo to Guatemala City takes 3h 30m
There are direct flights on this route 1 day a week: Sa
The distance between Santo Domingo and Guatemala City is 2232km (1384 miles). There are 5 direct flights from Santo Domingo to Guatemala City. The time difference between Santo Domingo and Guatemala City is 2h. Flights from Santo Domingo begin at 7:15 AM. The latest flight from Santo Domingo departs at 4:00 PM
We couldn't find any special offers for flights from Santo Domingo to Guatemala City