starting at $29
starting at $38
Compare airlines, prices, and flight durations for your trip
A non-stop flight is the most convenient and comfortable way to fly from Santiago to Mendoza, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Mendoza:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Looking for cheap flights from Santiago, Chile to Mendoza, Argentina? Look no further! Our air ticket search website provides you with the best deals and offers on this popular route. With convenient flight options, you can easily plan your journey without burning a hole in your pocket. Discover the stunning landscapes of Mendoza, famous for its world-class wineries and breathtaking Andes Mountains. Whether you're a wine enthusiast or an adventure seeker, Mendoza has something for everyone. Our user-friendly platform allows you to compare prices from various airlines, ensuring that you find the most affordable options. Take advantage of our advanced search filters to customize your travel preferences and find the best flight for your budget. Don't miss out on the opportunity to explore Mendoza while saving money on your airfare. Book your cheap flights from Santiago to Mendoza through our website today and embark on an unforgettable journey.
The route Santiago — Mendoza is served by several airlines: Sky Airline and B&H Airlines. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $29 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.
starting at $29
starting at $38
Santiago — Mendoza
01/19/2026
Departure
Direct flight
H2527
starting at $29
Santiago — Mendoza
03/15/2026
Departure
Direct flight
JA720
starting at $38
Santiago — Mendoza
02/03/2026
Departure
Direct flight
H2527
starting at $39
Santiago — Mendoza
03/16/2026
Departure
Direct flight
H2525
starting at $40
Santiago — Mendoza
03/04/2026
Departure
Direct flight
H2527
starting at $41
Santiago — Mendoza
03/09/2026
Departure
Direct flight
H2527
starting at $41
Santiago — Mendoza
02/20/2026
Departure
Direct flight
H2527
starting at $41
Santiago — Mendoza
03/01/2026
Departure
Direct flight
H2525
starting at $41
Santiago — Mendoza
02/19/2026
Departure
Direct flight
H2525
starting at $42
Santiago — Mendoza
02/21/2026
Departure
Direct flight
H2527
starting at $42
Sky Airline
Every day
starting at $52
LATAM Chile
Su, Mo, Tu, We, Th, and Fr
starting at $56
The cheapest flight ticket from Santiago to Mendoza according to data for the last 48 hours costs $29
Often the best time to buy tickets from Santiago to Mendoza is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Mendoza can be found flying in these months: January, March, February.
The fastest flights from Santiago to Mendoza start from 1 hour 4 minutes in the air.
The following airlines operate direct flights on the route Santiago — Mendoza: Sky Airline, B&H Airlines
The minimum one-way ticket price from Santiago to Mendoza is $48 (January 2026), while the maximum is $54 (February 2026). On average, a ticket costs $51–$105.
The cheapest one-way flight from Santiago to Mendoza departs on 01/19/2026, is operated by Sky Airline and costs $29
The cheapest roundtrip flight from Santiago to Mendoza departs on 02/10/2026, is operated by Sky Airline and costs $112
Fastest flight from Santiago to Mendoza takes 1h 4m
There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa
The distance between Santiago and Mendoza is 175km (109 miles). The average flight duration is 1h 5m. There are 28 direct flights from Santiago to Mendoza. The time difference between Santiago and Mendoza is 1h. Flights from Santiago begin at 6:56 AM. The latest flight from Santiago departs at 7:05 PM
We couldn't find any special offers for flights from Santiago to Mendoza