Schedule of direct flights from Santiago to La Serena
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to La Serena:
Santiago airports overview
La Serena airports overview
Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Santiago to La Serena
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Alternative routes
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Cheapest one way flight
$27
LATAM Chile
Direct flight
1h 10m
04/30/2025
The cheapest one-way flight from Santiago to La Serena departs on 04/30/2025, is operated by LATAM Chile and costs $27
Cheapest round trip flight
$41
Sky Airline
Direct flight
2h 9m
05/16/2025
The cheapest roundtrip flight from Santiago to La Serena departs on 05/16/2025, is operated by Sky Airline and costs $41
The fastest flight
1h 10m
Fastest flight from Santiago to La Serena takes 1h 10m
Direct flights
Once a week
There are direct flights on this route 1 day a week: We
Earliest flight
7:47 AM
Latest flight
8:31 PM
Direct flights count
70
Distance
393km
Timezone difference
0h
The distance between Santiago and La Serena is 393km (244 miles).There are 70 direct flights from Santiago to La Serena.Santiago and La Serena are in the same time zone.Flights from Santiago begin at 7:47 AM.The latest flight from Santiago departs at 8:31 PM.
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to La Serena. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Santiago to La Serena
Below you will find a list of airlines operating flights on the Santiago — La Serena route and the starting prices for flights of each specific airline on it.
A direct flight is the most convenient and comfortable way to fly from Santiago to La Serena, despite the fact that sometimes flights with transfers can cost significantly less.
Santiago — La Serena
SCL — LSC
04/30/2025
Departure date
Direct flight
LA104
Starting at $60
Santiago — La Serena
SCL — LSC
01/14/2026
Departure date
Direct flight
H21720
Starting at $55
How much is the cheapest flight ticket from Santiago to La Serena?
The cheapest flight ticket from Santiago to La Serena according to data for the last 48 hours costs $27
When is the best time to buy air tickets on the route Santiago — La Serena?
Often the best time to buy tickets from Santiago to La Serena is 2 months before departure.
How long does it take to fly from Santiago to La Serena?
The fastest flights from Santiago to La Serena start from 1 hour 10 minutes in the air.
Which airline can fly direct from Santiago to La Serena?
The following airlines operate direct flights on the route Santiago — La Serena: LATAM Chile, Sky Airline
