LATAM Chile
Every day
starting at $48
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to La Serena. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Santiago to La Serena, despite the fact that sometimes flights with transfers can cost significantly less.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
LATAM Chile
Every day
starting at $48
The only airline operating direct flights from Santiago to La Serena is LATAM Chile. Flights operate every day.
Santiago — La Serena
07/16/2026
Departure
Direct flight
H21742
starting at $50
Santiago — La Serena
07/18/2026
Departure
Direct flight
JA612
starting at $41
Santiago — La Serena
07/20/2026
Departure
Direct flight
JA610
starting at $59
Santiago — La Serena
09/04/2026
Departure
Direct flight
LA110
starting at $97
Santiago — La Serena
09/05/2026
Departure
Direct flight
LA106
starting at $37
The Santiago — La Serena route is served by multiple airlines, including Sky Airline, B&H Airlines, and LATAM Chile. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $19, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.
The cheapest one-way flight from Santiago to La Serena departs on 09/04/2026, is operated by B&H Airlines and costs $19
There is no information about the cheapest roundtrip flight from Santiago to La Serena
Fastest flight from Santiago to La Serena takes 1h 11m
There are direct flights on this route 4 days a week: Mo, Th, Fr, and Sa
The distance between Santiago and La Serena is 393km (244 miles). There are 61 direct flights from Santiago to La Serena. Santiago and La Serena are in the same time zone. Flights from Santiago begin at 7:49 AM. The latest flight from Santiago departs at 9:05 PM
The cheapest flight ticket from Santiago to La Serena according to data for the last 48 hours costs $19
Often the best time to buy tickets from Santiago to La Serena is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to La Serena can be found flying in these months: July, February.
The fastest flights from Santiago to La Serena start from 1 hour 11 minutes in the air.
The following airlines operate direct flights on the route Santiago — La Serena: Sky Airline, B&H Airlines, LATAM Chile
In different months, ticket prices from Santiago to La Serena vary: minimum — $23 (July 2026), maximum — $40 (February 2027). Typically, the flight costs $31–$40.
We couldn't find any special offers for flights from Santiago to La Serena