Airlines operating on route
Below you will find a list of airlines operating flights on the Santiago — Antofagasta route and the starting prices for flights of each specific airline on it.
Starting at $22
Starting at $39
Helping travelers to find the best flight offers
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to Antofagasta. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Santiago to Antofagasta
Below you will find a list of airlines operating flights on the Santiago — Antofagasta route and the starting prices for flights of each specific airline on it.
Starting at $22
Starting at $39
A direct flight is the most convenient and comfortable way to fly from Santiago to Antofagasta, despite the fact that sometimes flights with transfers can cost significantly less.
Santiago — Antofagasta
11/22/2025
Departure
Direct flight
JA52
Starting at $22
Santiago — Antofagasta
09/17/2025
Departure
Direct flight
JA56
Starting at $37
Santiago — Antofagasta
09/18/2025
Departure
Direct flight
JA56
Starting at $37
Santiago — Antofagasta
09/30/2025
Departure
Direct flight
H2450
Starting at $39
Santiago — Antofagasta
12/14/2025
Departure
Direct flight
H21714
Starting at $40
Santiago — Antofagasta
12/15/2025
Departure
Direct flight
H21710
Starting at $40
Santiago — Antofagasta
08/20/2025
Departure
Direct flight
H2290
Starting at $44
Santiago — Antofagasta
09/02/2025
Departure
Direct flight
H2270
Starting at $44
Santiago — Antofagasta
08/07/2025
Departure
Direct flight
H2290
Starting at $45
Santiago — Antofagasta
08/08/2025
Departure
Direct flight
H2288
Starting at $45
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Antofagasta:
Unable to find information about the schedule of direct flights from
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The cheapest one-way flight from Santiago to Antofagasta departs on 11/22/2025, is operated by B&H Airlines and costs $22
The cheapest roundtrip flight from Santiago to Antofagasta departs on 09/05/2025, is operated by B&H Airlines and costs $73
Fastest flight from Santiago to Antofagasta takes 2h 1m
There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa
The distance between Santiago and Antofagasta is 1108km (687 miles). There are 132 direct flights from Santiago to Antofagasta. Santiago and Antofagasta are in the same time zone. Flights from Santiago begin at 4:00 AM. The latest flight from Santiago departs at 9:19 PM.
We couldn't find any special offers for flights from Santiago to Antofagasta
The cheapest flight ticket from Santiago to Antofagasta according to data for the last 48 hours costs $22
Often the best time to buy tickets from Santiago to Antofagasta is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Antofagasta can be found flying in these months: December, September.
The fastest flights from Santiago to Antofagasta start from 2 hours 1 minute in the air.
The following airlines operate direct flights on the route Santiago — Antofagasta: B&H Airlines, Sky Airline
