Sky Airline
Every day
starting at $56
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santiago to Antofagasta. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
The cost of a one-way flight from Santiago to Antofagasta ranges from $33 (July 2026) to $65 (January 2027). On average, the ticket price is about $49–$65.
A non-stop flight is the most convenient and comfortable way to fly from Santiago to Antofagasta, despite the fact that sometimes flights with transfers can cost significantly less.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Sky Airline
Every day
starting at $56
The only airline operating direct flights from Santiago to Antofagasta is Sky Airline. Flights operate every day.
Santiago — Antofagasta
01/10/2027
Departure
Direct flight
LA350
starting at $138
starting at $65
On the Santiago — Antofagasta route, flights are operated only by LATAM Chile. This simplifies the choice for passengers, as all tickets come from a single trusted carrier. Our service lets you instantly check fares for upcoming dates and find the most advantageous option. The minimum ticket price starts at $65, making this trip affordable for a wide range of travelers. To save even more, we recommend booking early and keeping an eye on promotions — LATAM Chile regularly offers special deals.
The cheapest flight ticket from Santiago to Antofagasta according to data for the last 48 hours costs $65
Often the best time to buy tickets from Santiago to Antofagasta is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Antofagasta can be found flying in these months: July, January.
The fastest flights from Santiago to Antofagasta start from 2 hours 1 minute in the air.
The following airlines operate direct flights on the route Santiago — Antofagasta: LATAM Chile
The cheapest one-way flight from Santiago to Antofagasta departs on 01/10/2027, is operated by LATAM Chile and costs $65
There is no information about the cheapest roundtrip flight from Santiago to Antofagasta
Fastest flight from Santiago to Antofagasta takes 2h 1m
There are direct flights on this route 1 day a week: Su
The distance between Santiago and Antofagasta is 1108km (687 miles). There are 144 direct flights from Santiago to Antofagasta. Santiago and Antofagasta are in the same time zone. Flights from Santiago begin at 4:31 AM. The latest flight from Santiago departs at 10:45 PM
We couldn't find any special offers for flights from Santiago to Antofagasta