Cheap Flights from Santa Cruz to Sao Paulo — $257

The Santa Cruz — Sao Paulo route is served by a wide range of airlines: 5 in total, including Gol Transportes Aéreos, Boliviana de Aviación, Avianca, Aerolineas Argentinas, and LATAM Chile. Competition among carriers gives passengers the opportunity to find tickets at attractive fares — with prices starting from $257. Our service helps compare all available offers within seconds and choose the most convenient option. You can filter flights by price, departure time, or baggage rules to make your trip as comfortable as possible. With so many airlines, there’s always a chance to catch special promotions and save.

Santa Cruz de la Sierra is mainly served by Viru Viru International (VVI), the region’s principal international gateway and long-haul hub, while the smaller El Trompillo (SRZ) tends to handle limited domestic and charter services. VVI typically hosts major carriers and international connections and can be pricier on average than domestic-only airports; it lies about 20–30 km (30–45 minutes) east of downtown. Ground options include airport buses, taxis and app-based rideshares with fares varying widely, and private transfers often taking 30–45 minutes depending on traffic. El Trompillo is much closer to the city center (around 5–10 minutes), often cheaper for short hops, but offers fewer flight choices and more basic facilities. Pros: VVI provides broader connectivity and more passenger services; El Trompillo can be more convenient for quick domestic trips.

São Paulo is served by two main airports with different roles. São Paulo–Guarulhos (GRU) is the international gateway and busiest hub, typically handling most long-haul and full-service carriers as well as some domestic flights; it sits about 25–30 km northeast of the city center and can be reached by bus, airport shuttle, taxi or rideshare in roughly 40–60 minutes depending on traffic (airport buses and shared shuttles usually cost modest fares, while taxis and app cars are pricier). Congonhas (CGH) functions as the city’s domestic and business-focused airport, nearer to downtown at about 8–10 km and reachable in 15–30 minutes; it’s often used by budget and major Brazilian carriers for short hops. Pros of GRU include wide international connections and extensive services, while its distance and traffic can add time; Congonhas offers convenience and quicker access but can be crowded and has more limited long-haul options.