Cheap Flights from Pittsburgh to Saint Louis

Cheapest flights from Pittsburgh to Saint Louis

Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Pittsburgh to Saint Louis. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.

Cheapest one way flight

$347

American Airlines

1 layover

4h 54m

05/19/2026

The cheapest one-way flight from Pittsburgh to Saint Louis departs on 05/19/2026, is operated by American Airlines and costs $347

Cheapest round trip flight

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There is no information about the cheapest roundtrip flight from Pittsburgh to Saint Louis

The fastest flight

4h 54m

Fastest flight from Pittsburgh to Saint Louis takes 4h 54m

Direct flights

Once a week

There are direct flights on this route 1 day a week: Tu

Earliest flight

6:55 AM

Latest flight

8:05 PM

Direct flights count

4

Distance

897km

Timezone difference

1h

The distance between Pittsburgh and Saint Louis is 897km (556 miles). There are 4 direct flights from Pittsburgh to Saint Louis. The time difference between Pittsburgh and Saint Louis is 1h. Flights from Pittsburgh begin at 6:55 AM. The latest flight from Pittsburgh departs at 8:05 PM

Remember that on average the ideal time to book flights is 2 months before departure!

Airfare from Pittsburgh to Saint Louis by month

We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Pittsburgh to Saint Louis

May 2026

Lowest price

on average:

$127

Avg Price

Airlines operating on route

The Pittsburgh — Saint Louis route is served by multiple airlines, including Southwest Airlines and American Airlines. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $347, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.

Southwest Airlines

starting at $516

American Airlines

starting at $347

Non-stop flights from Pittsburgh to Saint Louis

A non-stop flight is the most convenient and comfortable way to fly from Pittsburgh to Saint Louis, despite the fact that sometimes flights with transfers can cost significantly less.

Pittsburgh — Saint Louis

PIT — STL

05/19/2026

Departure

Direct flight

WN3945

starting at $516

Schedule of direct flights from Pittsburgh to Saint Louis

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Pittsburgh airports overview

Allegheny County Airport

•

AGC

12km

Near Pittsburgh in West Mifflin, Pennsylvania, serving general aviation and corporate flights as a reliever for the metropolitan area; convenient for private and business travel to downtown Pittsburgh.

Pittsburgh International Airport

•

PIT

23km

•

Saint Louis airports overview

Lambert-St. Louis International Airport

•

STL

20km

Serving St. Louis, Missouri, and the surrounding metro area, it handles domestic and limited international flights with major carriers, a compact terminal, and convenient access to downtown.

Spirit of St. Louis Airport

•

SUS

20km

Serving the St. Louis metro in western St. Louis County, Missouri, primarily a reliever and general aviation field with FBO services, hangars and private-charter operations.

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Frequently asked questions (FAQ)

Answers to questions about the route that travelers are most interested in.

What is the cheapest price for flights from Pittsburgh to Saint Louis?

The cheapest flight ticket from Pittsburgh to Saint Louis according to data for the last 48 hours costs $347

When is the best time to buy air tickets on the route Pittsburgh — Saint Louis?

Often the best time to buy tickets from Pittsburgh to Saint Louis is 2 months before departure.

When is the cheapest time of year to fly from Pittsburgh to Saint Louis?

Based on statistics over the past years, the lowest prices for flights from Pittsburgh to Saint Louis can be found flying in these months: May.

How long does it take to fly from Pittsburgh to Saint Louis?

The fastest flights from Pittsburgh to Saint Louis start from 4 hours 54 minutes in the air.

Which airline can fly direct from Pittsburgh to Saint Louis?

The following airlines operate direct flights on the route Pittsburgh — Saint Louis: Southwest Airlines

Special offers and sales on air tickets from Pittsburgh to Saint Louis

We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.

We couldn't find any special offers for flights from Pittsburgh to Saint Louis

Alternative routes

Baltimore ➜ Saint Louis•Charlottesville ➜ Saint Louis•Charleston ➜ Saint Louis•Erie ➜ Saint Louis•Hagerstown ➜ Saint Louis•Lancaster ➜ Saint Louis•London ➜ Saint Louis•Pittsburgh ➜ Nashville•Pittsburgh ➜ Burlington•Pittsburgh ➜ Chicago•Pittsburgh ➜ Cedar Rapids•Pittsburgh ➜ Champaign•Pittsburgh ➜ Evansville•Pittsburgh ➜ Indianapolis•Pittsburgh ➜ Memphis

•••••••••••••••••••

Cheapest one way flight

$347

American Airlines

1 layover

4h 54m

05/19/2026

The cheapest one-way flight from Pittsburgh to Saint Louis departs on 05/19/2026, is operated by American Airlines and costs $347

Cheapest round trip flight

—

There is no information about the cheapest roundtrip flight from Pittsburgh to Saint Louis

The fastest flight