A direct flight is the most convenient and comfortable way to fly from Pisa to Brussels, despite the fact that sometimes flights with transfers can cost significantly less.
Schedule of direct flights from Pisa to Brussels
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Pisa to Brussels:
Pisa airports overview
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Brussels airports overview
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Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Pisa to Brussels
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Alternative routes
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Cheapest one way flight
$35
Ryanair
Direct flight
1h 40m
12/19/2025
The cheapest one-way flight from Pisa to Brussels departs on 12/19/2025, is operated by Ryanair and costs $35
Cheapest round trip flight
$90
Ryanair
Direct flight
3h 20m
02/06/2026
The cheapest roundtrip flight from Pisa to Brussels departs on 02/06/2026, is operated by Ryanair and costs $90
The fastest flight
1h 40m
Fastest flight from Pisa to Brussels takes 1h 40m
Direct flights
Several times a week
There are direct flights on this route 3 days a week: Tu, We, and Fr
Earliest flight
6:00 AM
Latest flight
9:15 PM
Direct flights count
15
Distance
916km
Timezone difference
0h
The distance between Pisa and Brussels is 916km (568 miles). There are 15 direct flights from Pisa to Brussels. Pisa and Brussels are in the same time zone. Flights from Pisa begin at 6:00 AM. The latest flight from Pisa departs at 9:15 PM
The route Pisa — Brussels is served by several airlines: Air Malta, Ryanair, and LC Busre SAC. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $35 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.
We couldn't find any special offers for flights from Pisa to Brussels
How much is the cheapest flight ticket from Pisa to Brussels?
The cheapest flight ticket from Pisa to Brussels according to data for the last 48 hours costs $35
When is the best time to buy air tickets on the route Pisa — Brussels?
Often the best time to buy tickets from Pisa to Brussels is 2 months before departure.
When is the cheapest time of year to fly from Pisa to Brussels?
Based on statistics over the past years, the lowest prices for flights from Pisa to Brussels can be found flying in these months: November, January, December.
How long does it take to fly from Pisa to Brussels?
The fastest flights from Pisa to Brussels start from 1 hour 40 minutes in the air.
Which airline can fly direct from Pisa to Brussels?
The following airlines operate direct flights on the route Pisa — Brussels: Air Malta, Ryanair
The minimum one-way ticket price from Pisa to Brussels is $26 (November 2025), while the maximum is $53 (December 2025). On average, a ticket costs $36–$82.
