Cheap Flights from Panama City to Sao Paulo Starting at $273

The route Panama City — Sao Paulo is served by several airlines: Copa Airlines and Avianca. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $273 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.

Panama City is primarily served by Tocumen International Airport (PTY), the region’s main international hub that typically handles long-haul and connecting flights for legacy carriers and major Latin American airlines. A secondary option is Albrook “Marcos A. Gelabert” (PAC), which is usually a domestic and low-cost alternative for short regional hops. Tocumen sits about 24 km (roughly 30–45 minutes by car) from downtown Panama City; taxis and ride-hailing services are common, with fares generally higher than local buses—bus and metro connections can be cheaper but take longer. Albrook is much closer, often 5–15 minutes to the city center by taxi or a short bus ride. Pros: Tocumen offers extensive international connections and amenities; Albrook is convenient for quick domestic trips. Cons: Tocumen can feel busy and farther from the city, while Albrook has limited international service and fewer facilities.

São Paulo is served by two main airports with different roles. São Paulo–Guarulhos International (GRU) is the primary international hub, typically handling most long-haul and full-service carriers such as LATAM, Gol’s international partners, and various global airlines; it’s about 25–30 km (roughly 40–50 minutes by road) from downtown, reachable by airport bus, taxi/Ride-hailing or the airport rail link with fares usually in the low to mid-range for public transport. Congonhas (CGH) functions more as a domestic/business-oriented airport favored by short-haul and legacy carriers; it sits much closer to the city (around 8 km, 15–25 minutes by car) and can be faster for business trips. GRU can be more comprehensive but busier and sometimes pricier, while Congonhas offers convenience for central arrivals but is limited in international connections.