Cheap Flights from Panama City to Sao Paulo — $276
Compare airlines, prices, and flight durations for your trip
Cheapest flights from Panama City to Sao Paulo
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Panama City to Sao Paulo. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
Remember that on average the ideal time to book flights is 2 months before departure!
A non-stop flight is the most convenient and comfortable way to fly from Panama City to Sao Paulo, despite the fact that sometimes flights with transfers can cost significantly less.
Schedule of direct flights from Panama City to Sao Paulo
The only airline operating direct flights from Panama City to Sao Paulo is Copa Airlines. Flights operate on Monday, Tuesday, and Thursday.
Panama City airports overview
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Sao Paulo airports overview
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Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Panama City to Sao Paulo
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Alternative routes
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Cheapest one way flight
$276
Avianca
1 layover
13 hours
09/29/2026
The cheapest one-way flight from Panama City to Sao Paulo departs on 09/29/2026, is operated by Avianca and costs $276
Cheapest round trip flight
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There is no information about the cheapest roundtrip flight from Panama City to Sao Paulo
The fastest flight
10h 20m
Fastest flight from Panama City to Sao Paulo takes 10h 20m
Direct flights
Several times a week
There are direct flights on this route 2 days a week: Tu and We
Earliest flight
12:00 PM
Latest flight
9:40 PM
Direct flights count
10
Distance
5089km
Timezone difference
2h
The distance between Panama City and Sao Paulo is 5089km (3155 miles). There are 10 direct flights from Panama City to Sao Paulo. The time difference between Panama City and Sao Paulo is 2h. Flights from Panama City begin at 12:00 PM. The latest flight from Panama City departs at 9:40 PM
The route Panama City — Sao Paulo is served by several airlines: Copa Airlines and Avianca. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $276 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.
Panama City is primarily served by Tocumen International Airport (PTY), the region’s main international hub that typically handles long-haul and connecting flights for legacy carriers and major Latin American airlines. A secondary option is Albrook “Marcos A. Gelabert” (PAC), which is usually a domestic and low-cost alternative for short regional hops. Tocumen sits about 24 km (roughly 30–45 minutes by car) from downtown Panama City; taxis and ride-hailing services are common, with fares generally higher than local buses—bus and metro connections can be cheaper but take longer. Albrook is much closer, often 5–15 minutes to the city center by taxi or a short bus ride. Pros: Tocumen offers extensive international connections and amenities; Albrook is convenient for quick domestic trips. Cons: Tocumen can feel busy and farther from the city, while Albrook has limited international service and fewer facilities.
São Paulo is served by two main airports with different roles. São Paulo–Guarulhos International (GRU) is the primary international hub, typically handling most long-haul and full-service carriers such as LATAM, Gol’s international partners, and various global airlines; it’s about 25–30 km (roughly 40–50 minutes by road) from downtown, reachable by airport bus, taxi/Ride-hailing or the airport rail link with fares usually in the low to mid-range for public transport. Congonhas (CGH) functions more as a domestic/business-oriented airport favored by short-haul and legacy carriers; it sits much closer to the city (around 8 km, 15–25 minutes by car) and can be faster for business trips. GRU can be more comprehensive but busier and sometimes pricier, while Congonhas offers convenience for central arrivals but is limited in international connections.
We couldn't find any special offers for flights from Panama City to Sao Paulo
Flights from Panama City to Sao Paulo from $276 – Compare Airfares | Flaut.Travel
September 2026
Lowest price
on average:
$293
June 2026
Highest price
on average:
$445
Avg Price
What is the cheapest price for flights from Panama City to Sao Paulo?
The cheapest flight ticket from Panama City to Sao Paulo according to data for the last 48 hours costs $276
When is the best time to buy air tickets on the route Panama City — Sao Paulo?
Often the best time to buy tickets from Panama City to Sao Paulo is 2 months before departure.
When is the cheapest time of year to fly from Panama City to Sao Paulo?
Based on statistics over the past years, the lowest prices for flights from Panama City to Sao Paulo can be found flying in these months: September, June.
How long does it take to fly from Panama City to Sao Paulo?
The fastest flights from Panama City to Sao Paulo start from 10 hours 20 minutes in the air.
Which airline can fly direct from Panama City to Sao Paulo?
The following airlines operate direct flights on the route Panama City — Sao Paulo: Copa Airlines
The minimum one-way ticket price from Panama City to Sao Paulo is $293 (September 2026), while the maximum is $445 (June 2026). On average, a ticket costs $369–$445.
