Panama City — Manaus
11/27/2026
Departure
Direct flight
CM141
starting at $674
Panama City — Manaus
02/28/2027
Departure
Direct flight
CM141
starting at $783
Compare fares and flight options for Panama City — Manaus. Prices can change; check availability when searching.
A non-stop flight is the most convenient and comfortable way to fly from Panama City to Manaus, despite the fact that sometimes flights with transfers can cost significantly less.
Answers to questions about the route that travelers are most interested in.
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No monthly price comparison is available yet.
Panama City — Manaus
11/27/2026
Departure
Direct flight
CM141
starting at $674
Panama City — Manaus
02/28/2027
Departure
Direct flight
CM141
starting at $783
starting at $674
starting at $566
Copa Airlines
Su and Fr
starting at $674
The flight selection for Panama City — Manaus includes offers from Copa Airlines and Avianca. Compare the featured carriers: the cheapest ticket found costs $566.
Direct offers from Panama City to Manaus were found for these airlines: Copa Airlines: Su and Fr.
Weekdays and prices come from the offers found. This is not a complete schedule; availability and flight frequency can change.
The cheapest flight ticket from Panama City to Manaus according to data for the last 48 hours costs $566
The lowest prices in the available monthly data for Panama City — Manaus are in: November. Prices can change.
The shortest duration among the offers found for Panama City — Manaus is 21 hours 15 minutes, including connections if present.
Direct flight offers from Panama City to Manaus were found for: Copa Airlines
We couldn't find any special offers for flights from Panama City to Manaus
The cheapest one-way flight from Panama City to Manaus departs on 02/28/2027, is operated by Avianca and costs $566
There is no information about the cheapest roundtrip flight from Panama City to Manaus
Fastest flight from Panama City to Manaus takes 21h 15m
Direct offers were found on these weekdays: Su and Fr.
The found offers from Panama City to Manaus depart between 2:30 AM and 6:10 PM, in the origin city’s time zone. The straight-line distance between Panama City and Manaus is 2539km.
Direct-flight weekdays and the fastest option are based on the offers found.
Duration and departure times are based on found offers, not the full schedule. Times use the origin city’s time zone.