starting at $352
starting at $347
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Panama City to Guatemala City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
The minimum one-way ticket price from Panama City to Guatemala City is $277 (November 2026), while the maximum is $347 (January 2027). On average, a ticket costs $317–$673.
A non-stop flight is the most convenient and comfortable way to fly from Panama City to Guatemala City, despite the fact that sometimes flights with transfers can cost significantly less.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Flight prices from Panama City to Guatemala City barely change from month to month. You can comfortably choose any convenient dates — there won't be a significant overpayment.
There is a slight difference: it's a bit cheaper in October 2026–November 2026 (averaging $302) and slightly more in November 2026–January 2027 ($312). But overall, the difference is small.
On this route, you don't need to target specific months — prices are stable. The difference between the cheapest and most expensive period is only 3%. Book whenever it's convenient.
Monthly price variation is just 9.2%. Ticket costs on this route are among the most predictable.
The route Panama City — Guatemala City is served by several airlines: Copa Airlines and Avianca. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $347 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.
starting at $352
starting at $347
Panama City — Guatemala City
10/28/2026
Departure
Direct flight
CM380
starting at $484
Panama City — Guatemala City
10/29/2026
Departure
Direct flight
CM390
starting at $537
Panama City — Guatemala City
10/31/2026
Departure
Direct flight
CM390
starting at $920
Panama City — Guatemala City
11/01/2026
Departure
Direct flight
CM390
starting at $638
Panama City — Guatemala City
11/02/2026
Departure
Direct flight
CM390
starting at $638
Panama City — Guatemala City
11/03/2026
Departure
Direct flight
CM380
starting at $497
Panama City — Guatemala City
11/04/2026
Departure
Direct flight
CM390
starting at $544
Panama City — Guatemala City
12/27/2026
Departure
Direct flight
CM390
starting at $518
Panama City — Guatemala City
12/29/2026
Departure
Direct flight
CM391
starting at $368
Panama City — Guatemala City
01/12/2027
Departure
Direct flight
CM380
starting at $476
There are most likely no direct flights on the Panama City — Guatemala City route
The cheapest flight ticket from Panama City to Guatemala City according to data for the last 48 hours costs $347
Often the best time to buy tickets from Panama City to Guatemala City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Panama City to Guatemala City can be found flying in these months: November, October, January.
The fastest flights from Panama City to Guatemala City start from 4 hours 2 minutes in the air.
The following airlines operate direct flights on the route Panama City — Guatemala City: Copa Airlines
All airports
The cheapest one-way flight from Panama City to Guatemala City departs on 01/21/2027, is operated by Avianca and costs $347
The cheapest roundtrip flight from Panama City to Guatemala City departs on 12/25/2026, is operated by TACA Airlines and costs $296
Fastest flight from Panama City to Guatemala City takes 4h 2m
There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa
The distance between Panama City and Guatemala City is 1349km (836 miles). There are 48 direct flights from Panama City to Guatemala City. The time difference between Panama City and Guatemala City is 1h. Flights from Panama City begin at 7:24 AM. The latest flight from Panama City departs at 9:45 PM
We couldn't find any special offers for flights from Panama City to Guatemala City