Compare airlines, prices, and flight durations for your trip
The minimum one-way ticket price from Palermo to Istanbul is $85 (April 2026), while the maximum is $162 (August 2026). On average, a ticket costs $106–$212.
A non-stop flight is the most convenient and comfortable way to fly from Palermo to Istanbul, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Palermo to Istanbul:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Turkish Airlines
Su, Mo, We, and Fr
starting at $160
Palermo — Istanbul
04/01/2026
Departure
Direct flight
TK1376
starting at $217
Palermo — Istanbul
04/11/2026
Departure
Direct flight
TK1376
starting at $207
Palermo — Istanbul
05/03/2026
Departure
Direct flight
TK1374
starting at $458
Palermo — Istanbul
05/13/2026
Departure
Direct flight
TK1376
starting at $180
Palermo — Istanbul
06/18/2026
Departure
Direct flight
TK1374
starting at $206
Palermo — Istanbul
06/26/2026
Departure
Direct flight
TK1374
starting at $284
Palermo — Istanbul
06/27/2026
Departure
Direct flight
TK1376
starting at $210
Palermo — Istanbul
06/30/2026
Departure
Direct flight
TK1376
starting at $193
Palermo — Istanbul
07/18/2026
Departure
Direct flight
TK1376
starting at $421
Palermo — Istanbul
08/07/2026
Departure
Direct flight
TK1374
starting at $441
starting at $177
starting at $79
starting at $101
starting at $102
starting at $110
starting at $117
starting at $118
starting at $129
starting at $139
starting at $146
starting at $166
starting at $199
The Palermo — Istanbul route is served by a wide range of airlines: 12 in total, including Turkish Airlines, EasyJet, Ryanair, Volotea, Air Serbia, Wizz Air, Transavia, Scandinavian Airlines, ITA Airways, South African Express, LC Busre SAC, and Vueling. Competition among carriers gives passengers the opportunity to find tickets at attractive fares — with prices starting from $79. Our service helps compare all available offers within seconds and choose the most convenient option. You can filter flights by price, departure time, or baggage rules to make your trip as comfortable as possible. With so many airlines, there’s always a chance to catch special promotions and save.
The cheapest flight ticket from Palermo to Istanbul according to data for the last 48 hours costs $79
Often the best time to buy tickets from Palermo to Istanbul is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Palermo to Istanbul can be found flying in these months: April, May, March.
The fastest flights from Palermo to Istanbul start from 2 hours 30 minutes in the air.
The following airlines operate direct flights on the route Palermo — Istanbul: Turkish Airlines
Looking for cheap flights from Palermo to Istanbul? Look no further! Our air ticket search website provides you with a hassle-free way to find the best deals on flights between these two beautiful cities. Explore the enchanting streets of Palermo, Italy, with its vibrant markets and stunning architecture, before immersing yourself in the rich cultural heritage of Istanbul, Turkey, where east meets west. With our optimized search engine, you can compare prices from various airlines and choose the most affordable option that suits your budget. Say goodbye to endless searching and let us help you book your dream trip at the lowest possible fare. Start your journey now and experience the wonders of Palermo and Istanbul without breaking the bank!
The cheapest one-way flight from Palermo to Istanbul departs on 05/14/2026, is operated by EasyJet and costs $79
The cheapest roundtrip flight from Palermo to Istanbul departs on 10/02/2026, is operated by Transavia and costs $245
Fastest flight from Palermo to Istanbul takes 2h 30m
There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa
The distance between Palermo and Istanbul is 1379km (855 miles). There are 5 direct flights from Palermo to Istanbul. The time difference between Palermo and Istanbul is 2h. Flights from Palermo begin at 9:30 AM. The latest flight from Palermo departs at 6:45 PM