Cheap Flights from Palermo to Istanbul — $78

Looking for cheap flights from Palermo to Istanbul? Look no further! Our air ticket search website provides you with a hassle-free way to find the best deals on flights between these two beautiful cities. Explore the enchanting streets of Palermo, Italy, with its vibrant markets and stunning architecture, before immersing yourself in the rich cultural heritage of Istanbul, Turkey, where east meets west. With our optimized search engine, you can compare prices from various airlines and choose the most affordable option that suits your budget. Say goodbye to endless searching and let us help you book your dream trip at the lowest possible fare. Start your journey now and experience the wonders of Palermo and Istanbul without breaking the bank!

The minimum one-way ticket price from Palermo to Istanbul is $99 (April 2026), while the maximum is $170 (July 2026). On average, a ticket costs $132–$269.

The Palermo — Istanbul route is served by a wide range of airlines: 11 in total, including Turkish Airlines, Ryanair, EasyJet, Wizz Air, South African Express, Volotea, Scandinavian Airlines, Air Serbia, ITA Airways, Transavia, and Aegean Airlines. Competition among carriers gives passengers the opportunity to find tickets at attractive fares — with prices starting from $78. Our service helps compare all available offers within seconds and choose the most convenient option. You can filter flights by price, departure time, or baggage rules to make your trip as comfortable as possible. With so many airlines, there’s always a chance to catch special promotions and save.

A non-stop flight is the most convenient and comfortable way to fly from Palermo to Istanbul, despite the fact that sometimes flights with transfers can cost significantly less.