starting at $200
starting at $280
starting at $331
starting at $337
starting at $446
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Mexico City to Santo Domingo. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
In different months, ticket prices from Mexico City to Santo Domingo vary: minimum — $190 (October 2026), maximum — $344 (November 2026). Typically, the flight costs $267–$344.
A non-stop flight is the most convenient and comfortable way to fly from Mexico City to Santo Domingo, despite the fact that sometimes flights with transfers can cost significantly less.
The only airline operating direct flights from Mexico City to Santo Domingo is Asian Air. Flights operate on Monday, Wednesday, Thursday, and Friday.
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The route Mexico City — Santo Domingo is served by many carriers — 5 in total, including Asian Air, Volaris, Aeromexico, VivaAerobus, and Copa Airlines. This gives passengers wide opportunities: from finding the lowest fare (from $200) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.
starting at $200
starting at $280
starting at $331
starting at $337
starting at $446
Mexico City — Santo Domingo
02/04/2027
Departure
Direct flight
DM4163
starting at $200
Mexico City — Santo Domingo
02/02/2027
Departure
Direct flight
DM4163
starting at $201
Mexico City — Santo Domingo
02/05/2027
Departure
Direct flight
DM4165
starting at $201
Mexico City — Santo Domingo
11/27/2026
Departure
Direct flight
DM4165
starting at $241
Mexico City — Santo Domingo
10/29/2026
Departure
Direct flight
DM4163
starting at $242
Mexico City — Santo Domingo
12/01/2026
Departure
Direct flight
DM4163
starting at $243
Mexico City — Santo Domingo
10/31/2026
Departure
Direct flight
DM4163
starting at $244
Mexico City — Santo Domingo
11/28/2026
Departure
Direct flight
DM4163
starting at $255
Mexico City — Santo Domingo
10/30/2026
Departure
Direct flight
DM4165
starting at $255
Mexico City — Santo Domingo
11/12/2026
Departure
Direct flight
DM4163
starting at $310
Asian Air
Mo, We, Th, and Fr
starting at $177
The cheapest flight ticket from Mexico City to Santo Domingo according to data for the last 48 hours costs $200
Often the best time to buy tickets from Mexico City to Santo Domingo is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Mexico City to Santo Domingo can be found flying in these months: October, November.
The fastest flights from Mexico City to Santo Domingo start from 4 hours 15 minutes in the air.
The following airlines operate direct flights on the route Mexico City — Santo Domingo: Asian Air
All airports
The cheapest one-way flight from Mexico City to Santo Domingo departs on 02/04/2027, is operated by Asian Air and costs $200
The cheapest roundtrip flight from Mexico City to Santo Domingo departs on 06/11/2027, is operated by Asian Air and costs $387
Fastest flight from Mexico City to Santo Domingo takes 4h 15m
There are direct flights on this route 4 days a week: Tu, Th, Fr, and Sa
The distance between Mexico City and Santo Domingo is 3068km (1902 miles). The average flight duration is 4h 38m. There are 11 direct flights from Mexico City to Santo Domingo. The time difference between Mexico City and Santo Domingo is 2h. Flights from Mexico City begin at 11:34 PM. The latest flight from Mexico City departs at 1:01 AM
We couldn't find any special offers for flights from Mexico City to Santo Domingo