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Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Mexico City to Santo Domingo. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Mexico City to Santo Domingo, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Mexico City to Santo Domingo:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
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Mexico City — Santo Domingo
07/25/2026
Departure
Direct flight
AM654
starting at $723
Mexico City — Santo Domingo
04/25/2026
Departure
Direct flight
DM4163
starting at $244
Mexico City — Santo Domingo
04/26/2026
Departure
Direct flight
AM654
starting at $604
Mexico City — Santo Domingo
04/28/2026
Departure
Direct flight
AM654
starting at $551
Mexico City — Santo Domingo
04/29/2026
Departure
Direct flight
AM654
starting at $472
Mexico City — Santo Domingo
05/01/2026
Departure
Direct flight
DM4165
starting at $420
Mexico City — Santo Domingo
05/08/2026
Departure
Direct flight
AM654
starting at $477
Mexico City — Santo Domingo
05/09/2026
Departure
Direct flight
AM654
starting at $486
Mexico City — Santo Domingo
05/13/2026
Departure
Direct flight
AM654
starting at $470
Mexico City — Santo Domingo
05/15/2026
Departure
Direct flight
DM4165
starting at $204
starting at $458
starting at $136
starting at $203
starting at $212
starting at $231
The route Mexico City — Santo Domingo is served by many carriers — 5 in total, including Aeromexico, Asian Air, Copa Airlines, Volaris, and Avianca. This gives passengers wide opportunities: from finding the lowest fare (from $136) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.
The cheapest one-way flight from Mexico City to Santo Domingo departs on 09/29/2026, is operated by Asian Air and costs $136
There is no information about the cheapest roundtrip flight from Mexico City to Santo Domingo
Fastest flight from Mexico City to Santo Domingo takes 4h 25m
There are direct flights on this route 6 days a week: Su, Mo, Tu, We, Fr, and Sa
The distance between Mexico City and Santo Domingo is 3062km (1898 miles). There are 13 direct flights from Mexico City to Santo Domingo. The time difference between Mexico City and Santo Domingo is 2h. Flights from Mexico City begin at 10:15 PM. The latest flight from Mexico City departs at 1:05 AM
The cheapest flight ticket from Mexico City to Santo Domingo according to data for the last 48 hours costs $136
Often the best time to buy tickets from Mexico City to Santo Domingo is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Mexico City to Santo Domingo can be found flying in these months: April, June, July.
The fastest flights from Mexico City to Santo Domingo start from 4 hours 25 minutes in the air.
The following airlines operate direct flights on the route Mexico City — Santo Domingo: Aeromexico, Asian Air
In different months, ticket prices from Mexico City to Santo Domingo vary: minimum — $178 (April 2026), maximum — $414 (December 2026). Typically, the flight costs $243–$434.
Flight prices from Mexico City to Santo Domingo are steadily rising: from April 2026 to December 2026, ticket costs increased by 133%. The sooner you book, the better the deal.
The most significant price increase was from June 2026 to December 2026 — up 116%. The best time to fly is April 2026–May 2026, when the average price is $198. In July 2026–December 2026, tickets cost around $315.
Given the rising prices, it's best not to delay your purchase. Flying in April 2026–May 2026 can save you up to 37% compared to the most expensive months.
Price variation across months on this route is 35.6%. Your choice of departure month significantly affects the total flight cost.