Aeromexico
Su, Mo, Tu, and Sa
starting at $208
Compare airlines, prices, and flight durations for your trip
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Mexico City to Santo Domingo. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Mexico City to Santo Domingo, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Mexico City to Santo Domingo:
•
•
•
•
•
•
Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Aeromexico
Su, Mo, Tu, and Sa
starting at $208
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Mexico City to Santo Domingo
Mexico City — Santo Domingo
01/19/2026
Departure
Direct flight
AM654
starting at $547
Mexico City — Santo Domingo
03/20/2026
Departure
Direct flight
AM654
starting at $553
Mexico City — Santo Domingo
03/27/2026
Departure
Direct flight
DM4069
starting at $202
starting at $547
starting at $168
The Mexico City — Santo Domingo route is served by multiple airlines, including Aeromexico and Asian Air. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $168, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.
The cheapest flight ticket from Mexico City to Santo Domingo according to data for the last 48 hours costs $168
Often the best time to buy tickets from Mexico City to Santo Domingo is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Mexico City to Santo Domingo can be found flying in these months: March.
The fastest flights from Mexico City to Santo Domingo start from 4 hours 15 minutes in the air.
The following airlines operate direct flights on the route Mexico City — Santo Domingo: Aeromexico, Asian Air
The cheapest one-way flight from Mexico City to Santo Domingo departs on 03/21/2026, is operated by Asian Air and costs $168
There is no information about the cheapest roundtrip flight from Mexico City to Santo Domingo
Fastest flight from Mexico City to Santo Domingo takes 4h 15m
There are direct flights on this route 2 days a week: Mo and Fr
The distance between Mexico City and Santo Domingo is 3062km (1898 miles). There are 13 direct flights from Mexico City to Santo Domingo. The time difference between Mexico City and Santo Domingo is 2h. Flights from Mexico City begin at 10:15 PM. The latest flight from Mexico City departs at 1:01 AM
We couldn't find any special offers for flights from Mexico City to Santo Domingo