There are most likely no direct flights on the Madrid — Santo Domingo route
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A non-stop flight is the most convenient and comfortable way to fly from Madrid to Santo Domingo, despite the fact that sometimes flights with transfers can cost significantly less.
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There are most likely no direct flights on the Madrid — Santo Domingo route
In different months, ticket prices from Madrid to Santo Domingo vary: minimum — $367 (September 2026), maximum — $701 (July 2026). Typically, the flight costs $540–$1,219.
On the Madrid — Santo Domingo route, prices first decline, hit a low, then start rising again. The middle of the period creates a price window — the best time to book.
Prices fall from July 2026 to September 2026 (48%), then rise from September 2026 to December 2026 (+70%). The best period is September 2026–October 2026 ($389), the most expensive is July 2026–August 2026 ($648).
The best time to buy is September 2026–October 2026, when prices are at their lowest. This can save you up to 40% compared to the expensive months (July 2026–August 2026).
Monthly price variation is 23.8%. On this route, your departure date noticeably affects the cost, and choosing wisely can lead to real savings.
Madrid — Santo Domingo
12/20/2026
Departure
Direct flight
IB263
starting at $885
Madrid — Santo Domingo
08/01/2026
Departure
Direct flight
2W3409
starting at $685
Madrid — Santo Domingo
03/01/2027
Departure
Direct flight
UX185
starting at $590
Madrid — Santo Domingo
05/05/2027
Departure
Direct flight
IB265
starting at $563
Madrid — Santo Domingo
08/06/2026
Departure
Direct flight
2W3409
starting at $644
Madrid — Santo Domingo
08/20/2026
Departure
Direct flight
UX185
starting at $510
Madrid — Santo Domingo
12/25/2026
Departure
Direct flight
IB265
starting at $804
Madrid — Santo Domingo
01/05/2027
Departure
Direct flight
UX089
starting at $623
Madrid — Santo Domingo
07/30/2026
Departure
Direct flight
IB263
starting at $857
Madrid — Santo Domingo
07/31/2026
Departure
Direct flight
IB263
starting at $988
starting at $563
starting at $385
starting at $510
starting at $484
starting at $600
starting at $623
starting at $679
The route Madrid — Santo Domingo is served by many carriers — 7 in total, including Iberia, Welcome Air, Air Europa, Avianca, Air Canada, Ryanair, and LASER Airlines. This gives passengers wide opportunities: from finding the lowest fare (from $385) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.
The cheapest flight ticket from Madrid to Santo Domingo according to data for the last 48 hours costs $385
Often the best time to buy tickets from Madrid to Santo Domingo is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Madrid to Santo Domingo can be found flying in these months: September, October, August.
The fastest flights from Madrid to Santo Domingo start from 8 hours 40 minutes in the air.
The following airlines operate direct flights on the route Madrid — Santo Domingo: Iberia, Welcome Air, Air Europa
The cheapest one-way flight from Madrid to Santo Domingo departs on 08/20/2026, is operated by Welcome Air and costs $385
The cheapest roundtrip flight from Madrid to Santo Domingo departs on 02/11/2027, is operated by Iberia and costs $726
Fastest flight from Madrid to Santo Domingo takes 8h 40m
There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa
The distance between Madrid and Santo Domingo is 6699km (4153 miles). The average flight duration is 9h 25m. There are 18 direct flights from Madrid to Santo Domingo. The time difference between Madrid and Santo Domingo is 5h. Flights from Madrid begin at 11:55 AM. The latest flight from Madrid departs at 4:10 PM
We couldn't find any special offers for flights from Madrid to Santo Domingo
