Iberia
Every day
starting at $467
Compare airlines, prices, and flight durations for your trip
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Madrid to Santo Domingo. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Madrid to Santo Domingo:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Iberia
Every day
starting at $467
A non-stop flight is the most convenient and comfortable way to fly from Madrid to Santo Domingo, despite the fact that sometimes flights with transfers can cost significantly less.
Madrid — Santo Domingo
03/07/2026
Departure
Direct flight
IB265
starting at $640
Madrid — Santo Domingo
03/08/2026
Departure
Direct flight
2W3409
starting at $368
Madrid — Santo Domingo
02/10/2026
Departure
Direct flight
IB265
starting at $492
Madrid — Santo Domingo
05/16/2026
Departure
Direct flight
IB265
starting at $543
Madrid — Santo Domingo
02/14/2026
Departure
Direct flight
UX89
starting at $620
Madrid — Santo Domingo
02/15/2026
Departure
Direct flight
UX89
starting at $576
Madrid — Santo Domingo
02/19/2026
Departure
Direct flight
IB265
starting at $536
Madrid — Santo Domingo
02/22/2026
Departure
Direct flight
IB265
starting at $449
Madrid — Santo Domingo
03/03/2026
Departure
Direct flight
UX089
starting at $434
Madrid — Santo Domingo
03/13/2026
Departure
Direct flight
IB265
starting at $431
starting at $431
starting at $363
starting at $434
starting at $367
starting at $418
The route Madrid — Santo Domingo is served by many carriers — 5 in total, including Iberia, Welcome Air, Air Europa, Avianca, and JetBlue Airways. This gives passengers wide opportunities: from finding the lowest fare (from $363) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.
The cheapest one-way flight from Madrid to Santo Domingo departs on 02/19/2026, is operated by Welcome Air and costs $363
The cheapest roundtrip flight from Madrid to Santo Domingo departs on 04/20/2026, is operated by JetBlue Airways and costs $696
Fastest flight from Madrid to Santo Domingo takes 9h 15m
There are direct flights on this route 5 days a week: Su, Tu, Th, Fr, and Sa
The distance between Madrid and Santo Domingo is 6699km (4153 miles). There are 26 direct flights from Madrid to Santo Domingo. The time difference between Madrid and Santo Domingo is 5h. Flights from Madrid begin at 11:55 AM. The latest flight from Madrid departs at 4:20 PM
We couldn't find any special offers for flights from Madrid to Santo Domingo
The cheapest flight ticket from Madrid to Santo Domingo according to data for the last 48 hours costs $363
Often the best time to buy tickets from Madrid to Santo Domingo is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Madrid to Santo Domingo can be found flying in these months: April, February, August.
The fastest flights from Madrid to Santo Domingo start from 9 hours 15 minutes in the air.
The following airlines operate direct flights on the route Madrid — Santo Domingo: Iberia, Welcome Air, Air Europa
In different months, ticket prices from Madrid to Santo Domingo vary: minimum — $430 (April 2026), maximum — $536 (November 2026). Typically, the flight costs $497–$505.
