Unable to find information about the schedule of direct flights from
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A non-stop flight is the most convenient and comfortable way to fly from Madrid to Santiago, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Madrid to Santiago:
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Answers to questions about the route that travelers are most interested in.
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Looking for cheap flights from Madrid, Spain to Santiago, Dominican Republic? Look no further! Our air ticket search website offers a wide range of affordable options for your travel needs. With our user-friendly interface, finding the best deals has never been easier. We understand that saving money is important, so we ensure that you get the most competitive prices on the market without compromising on quality. Whether you're planning a vacation or a business trip, our website can help you find the perfect flight. Don't waste time searching multiple websites; let us do the work for you. Book your cheap flight from Madrid to Santiago today and embark on an unforgettable journey without breaking the bank. Start your search now and experience the convenience of booking with us.
Unable to find information about the schedule of direct flights from
Madrid — Santiago
07/09/2026
Departure
Direct flight
UX119
starting at $773
Madrid — Santiago
01/24/2026
Departure
Direct flight
UX119
starting at $756
The Madrid — Santiago route is served by multiple airlines, including Air Europa, TAP Portugal, and Iberia. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $527, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.
The cheapest flight ticket from Madrid to Santiago according to data for the last 48 hours costs $527
Often the best time to buy tickets from Madrid to Santiago is 2 months before departure.
The fastest flights from Madrid to Santiago start from 8 hours 40 minutes in the air.
The following airlines operate direct flights on the route Madrid — Santiago: Air Europa
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Madrid to Santiago
The cheapest one-way flight from Madrid to Santiago departs on 01/24/2026, is operated by TAP Portugal and costs $527
The cheapest roundtrip flight from Madrid to Santiago departs on 03/10/2026, is operated by TAP Portugal and costs $777
Fastest flight from Madrid to Santiago takes 8h 40m
There are direct flights on this route 2 days a week: Th and Sa
The distance between Madrid and Santiago is 6692km (4149 miles). There are 1 direct flight from Madrid to Santiago. The time difference between Madrid and Santiago is 5h. Flights from Madrid begin at 3:25 PM. The latest flight from Madrid departs at 3:25 PM
We couldn't find any special offers for flights from Madrid to Santiago
