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Fly from Guayaquil to São Paulo with confidence — our search scans over 700 airlines, 50+ agencies and more than 5 top booking systems to find the best prices, schedules and ticket conditions tailored to your trip. Friendly filters and clear comparisons help you lock in the ideal flight fast, so you can focus on planning what to do once you land.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Guayaquil to Sao Paulo:
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We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The cheapest one-way flight from Guayaquil to Sao Paulo departs on 05/01/2026, is operated by LATAM Chile and costs $304
The cheapest roundtrip flight from Guayaquil to Sao Paulo departs on 01/24/2026, is operated by Avianca and costs $515
Fastest flight from Guayaquil to Sao Paulo takes 9h 55m
There are no direct flights on this route.
The distance between Guayaquil and Sao Paulo is 4298km (2665 miles). The time difference between Guayaquil and Sao Paulo is 2h
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Starting at $304
On the Guayaquil — Sao Paulo route, flights are operated only by LATAM Chile. This simplifies the choice for passengers, as all tickets come from a single trusted carrier. Our service lets you instantly check fares for upcoming dates and find the most advantageous option. The minimum ticket price starts at $304, making this trip affordable for a wide range of travelers. To save even more, we recommend booking early and keeping an eye on promotions — LATAM Chile regularly offers special deals.
José Joaquín de Olmedo International Airport (GYE) is the main international gateway for Guayaquil, serving as the city’s principal hub for both full-service and regional carriers as well as several low-cost airlines. Located about 5–7 km northwest of the historic center, the airport is typically reached in 15–25 minutes by taxi or rideshare; local buses and airport shuttles can take 30–45 minutes depending on traffic. Taxi fares are usually modest by international standards while private transfers and airport express options cost more. The terminal is generally compact and convenient for short connections, though peak hours can feel crowded; travellers trade quick access to the city for limited on-site dining and shopping compared with larger hubs.
Fly nonstop from Guayaquil to São Paulo for the fastest, most convenient way to link Ecuador’s coast with Brazil’s bustling metropolis — perfect for business trips or weekend getaways. Direct flights cut transfer stress and save hours compared with connections; while some multi-stop options can be cheaper, choosing a nonstop often means more comfort and valuable time back in your day.
São Paulo is served chiefly by three airports that cater to different traveler needs. São Paulo–Guarulhos (GRU) is the main international gateway and largest hub, typically handling most long-haul and full-service carriers; it’s about 25–35 km from downtown and can take 40–70 minutes by car depending on traffic. Options include airport buses (roughly 50–100 BRL), taxis or app rides and a fast rail line with variable fares, making it a solid choice for international connections though peak-hour congestion can add time. Congonhas (CGH) sits much closer to the city center—around 8–10 km—and is usually the busiest domestic airport, favored by short-haul and legacy carriers; road transfers often take 20–40 minutes with moderate fares, offering convenience for business travelers but limited long-haul services and fewer budget options. Viracopos (VCP) near Campinas operates as a secondary international/low-cost gateway and cargo hub about 90–110 km from São Paulo; it can be cheaper for some low-cost flights, though transfer times are longer (around 1.5–2.5 hours by shuttle or private transfer) and on-site amenities may be more limited compared with GRU.
We couldn't find any special offers for flights from Guayaquil to Sao Paulo
The cheapest flight ticket from Guayaquil to Sao Paulo according to data for the last 48 hours costs $304
Often the best time to buy tickets from Guayaquil to Sao Paulo is 2 months before departure.
The fastest flights from Guayaquil to Sao Paulo start from 9 hours 55 minutes in the air.
The following airlines operate direct flights on the route Guayaquil — Sao Paulo:
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Guayaquil to Sao Paulo