Starting at $260
Helping travelers to find the best flight offers
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Guayaquil to Santiago:
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Starting at $260
Below you will find a list of airlines operating flights on the Guayaquil — Santiago route and the starting prices for flights of each specific airline on it.
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Guayaquil to Santiago
Unable to find information about the schedule of direct flights from
Guayaquil — Santiago
04/01/2025
Departure date
Direct flight
LA1447
Starting at $470
Guayaquil — Santiago
04/02/2025
Departure date
Direct flight
LA1447
Starting at $398
Guayaquil — Santiago
08/14/2025
Departure date
Direct flight
LA1447
Starting at $302
A direct flight is the most convenient and comfortable way to fly from Guayaquil to Santiago, despite the fact that sometimes flights with transfers can cost significantly less.
The cheapest flight ticket from Guayaquil to Santiago according to data for the last 48 hours costs $302
Often the best time to buy tickets from Guayaquil to Santiago is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Guayaquil to Santiago can be found flying in these months: March.
The fastest flights from Guayaquil to Santiago start from 4 hours 53 minutes in the air.
The following airlines operate direct flights on the route Guayaquil — Santiago: LATAM Chile
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Guayaquil to Santiago. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
The cheapest one-way flight from Guayaquil to Santiago departs on 08/14/2025, is operated by LATAM Chile and costs $302
The cheapest roundtrip flight from Guayaquil to Santiago departs on 06/19/2025, is operated by Copa Airlines and costs $385
Fastest flight from Guayaquil to Santiago takes 4h 53m
There are direct flights on this route 1 day a week: Th
The distance between Guayaquil and Santiago is 3610km (2238 miles). There are 8 direct flights from Guayaquil to Santiago. The time difference between Guayaquil and Santiago is 1h . Flights from Guayaquil begin at 2:45 PM. The latest flight from Guayaquil departs at 2:45 PM.
We couldn't find any special offers for flights from Guayaquil to Santiago
