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Find the best flights from Quito to Santiago quickly and confidently — we search over 700 airlines, 50+ travel agencies, and more than 5 top booking systems to uncover the cheapest fares, ideal schedules, and flexible conditions. Whether you’re planning a business trip or a getaway to Chile, compare options in one place and book with ease.
The minimum one-way ticket price from Quito to Santiago is $242 (April 2026), while the maximum is $353 (March 2026). On average, a ticket costs $304–$668.
Fly nonstop from Quito to Santiago for the fastest, most convenient way to get between Ecuador and Chile — fewer hassles, no layovers, and more time to enjoy your trip. While connecting flights can sometimes be cheaper, a direct service saves hours and offers a more comfortable, predictable journey, perfect for business or leisure travelers ready to book.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Quito to Santiago:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The cheapest one-way flight from Quito to Santiago departs on 04/17/2026, is operated by B&H Airlines and costs $228
There is no information about the cheapest roundtrip flight from Quito to Santiago
Fastest flight from Quito to Santiago takes 10h 22m
There are no direct flights on this route.
The distance between Quito and Santiago is 3791km (2350 miles). The time difference between Quito and Santiago is 1h
The route Quito — Santiago is served by several airlines: B&H Airlines, LATAM Chile, and Avianca. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $228 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.
There appear to be no non-stop flights from Quito to Santiago at this time.... Well, or something went wrong on our side and we couldn't find anything
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Mariscal Sucre International Airport (UIO) is Quito’s main international gateway and typically serves as the country’s premium hub for long-haul and regional flights, with carriers ranging from full-service network airlines to low-cost regional operators. Located roughly 18–20 km east of the historic center, travel times by taxi or rideshare can be 30–50 minutes depending on traffic; airport buses and private shuttles may take a similar span and can be a more economical option. Expect fares to be mid-range for taxis and lower for shuttle services. Pros: modern facilities and many international connections; cons: altitude and occasional traffic congestion can add to transfer times.
The cheapest flight ticket from Quito to Santiago according to data for the last 48 hours costs $228
Often the best time to buy tickets from Quito to Santiago is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Quito to Santiago can be found flying in these months: April, September, March.
The fastest flights from Quito to Santiago start from 10 hours 22 minutes in the air.
The following airlines operate direct flights on the route Quito — Santiago:
Arturo Merino Benítez International Airport (SCL) is Chile’s primary international gateway and a full-service hub for LATAM and several global carriers, handling most long-haul and regional flights. Located about 15–20 km northwest of downtown Santiago, transfer times to the city center usually run 20–40 minutes depending on traffic; options include the official airport bus and private shuttles (roughly CLP fares for buses, higher for taxis/rideshares), and a newly extended rail link that can be faster during peak hours. For travelers, SCL typically offers a wide range of services and lounge access but can be busy at peak times and walking distances between gates may be significant. Aeropuerto Eulogio Sánchez (Concepción) is not in Santiago — Santiago is mainly served by SCL and nearby smaller airfields for general aviation. Santiago’s secondary options can include smaller regional airports used for charter or private flights; these tend to be budget-oriented or specialized, with limited scheduled service and fewer passenger facilities. Such airfields are often closer to outskirts and offer quick access for private flyers, though they lack frequent commercial connections and extensive ground transport links, making them less convenient for standard commercial travelers.
We couldn't find any special offers for flights from Quito to Santiago