Helping travelers to find the best flight offers
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Guayaquil to Panama City:
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Starting at $157
Unable to find information about the schedule of direct flights from
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Guayaquil to Panama City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
Below you will find a list of airlines operating flights on the Guayaquil — Panama City route and the starting prices for flights of each specific airline on it.
The cheapest one-way flight from Guayaquil to Panama City departs on 05/12/2025, is operated by Avianca and costs $163
The cheapest roundtrip flight from Guayaquil to Panama City departs on 04/21/2025, is operated by Avianca and costs $339
Fastest flight from Guayaquil to Panama City takes 5h 25m
There are no direct flights on this route.
The distance between Guayaquil and Panama City is 1238km (768 miles). There are 40 direct flights from Guayaquil to Panama City. Guayaquil and Panama City are in the same time zone. Flights from Guayaquil begin at 4:31 AM. The latest flight from Guayaquil departs at 6:32 PM.
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Guayaquil to Panama City
A direct flight is the most convenient and comfortable way to fly from Guayaquil to Panama City, despite the fact that sometimes flights with transfers can cost significantly less.
Guayaquil — Panama City
04/07/2025
Departure date
Direct flight
CM379
Starting at $255
Guayaquil — Panama City
06/01/2025
Departure date
Direct flight
CM377
Starting at $257
The cheapest flight ticket from Guayaquil to Panama City according to data for the last 48 hours costs $163
Often the best time to buy tickets from Guayaquil to Panama City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Guayaquil to Panama City can be found flying in these months: June, April.
The fastest flights from Guayaquil to Panama City start from 5 hours 25 minutes in the air.
The following airlines operate direct flights on the route Guayaquil — Panama City: Copa Airlines
We couldn't find any special offers for flights from Guayaquil to Panama City