Cheap Flights from Guayaquil to Panama City Starting at $182
Helping travelers to find the best flight offers
Cheapest flights from Guayaquil to Panama City
Fly from Guayaquil to Panama City with confidence — our search scans over 700 airlines, 50+ travel agencies, and more than 5 top booking systems to find the best prices, schedules, and booking conditions for your trip. Compare options in seconds and pick the flight that fits your budget and timing, then book quickly to secure the deal.
Remember that on average the ideal time to book flights is 2 months before departure!
The minimum one-way ticket price from Guayaquil to Panama City is $179 (January 2026), while the maximum is $215 (December 2025). On average, a ticket costs $183–$190.
Airlines operating on route
Direct Flights from Guayaquil to Panama City
Fly nonstop from Guayaquil to Panama City for the quickest, most convenient way to get between these vibrant cities — less travel time, fewer hassles, and more time to enjoy Panama’s sights. While connecting options can sometimes be cheaper, a direct flight means greater comfort and a simpler schedule, making it ideal for tight itineraries or relaxed travel plans.
Schedule of direct flights from Guayaquil to Panama City
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Guayaquil to Panama City:
Guayaquil airports overview
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Panama City airports overview
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Frequently asked questions (FAQ)
Answers to questions about the route that travelers are most interested in.
Special offers and sales on air tickets from Guayaquil to Panama City
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Alternative routes
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Cheapest one way flight
$182
Avianca
1 transfer
4h 55m
03/01/2026
The cheapest one-way flight from Guayaquil to Panama City departs on 03/01/2026, is operated by Avianca and costs $182
Cheapest round trip flight
$378
Avianca Ecuador
1 transfer
12h 5m
02/27/2026
The cheapest roundtrip flight from Guayaquil to Panama City departs on 02/27/2026, is operated by Avianca Ecuador and costs $378
The fastest flight
2h 10m
Fastest flight from Guayaquil to Panama City takes 2h 10m
Direct flights
Once a week
There are direct flights on this route 1 day a week: Su
Earliest flight
4:28 AM
Latest flight
3:35 AM
Average flight duration
5h 25m
Direct flights count
48
Distance
1238km
Timezone difference
0h
The distance between Guayaquil and Panama City is 1238km (768 miles). The average flight duration is 5h 25m. There are 48 direct flights from Guayaquil to Panama City. Guayaquil and Panama City are in the same time zone. Flights from Guayaquil begin at 4:28 AM. The latest flight from Guayaquil departs at 3:35 AM
January 2026
Lowest price
on average:
$179
December 2025
Highest price
on average:
$215
Avg Price
The route Guayaquil — Panama City is served by several airlines: Copa Airlines and Avianca. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $182 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.
José Joaquín de Olmedo International Airport (GYE) is Ecuador’s main gateway on the Pacific coast, serving both international flights and a busy mix of domestic services; it typically hosts full-service carriers as well as regional and low-cost operators. Located about 4–6 km northwest of central Guayaquil, the airport can be reached by taxi or rideshare in roughly 15–25 minutes depending on traffic, with fares commonly in a moderate range; public buses and airport shuttles provide lower-cost options though travel times can be longer. Facilities are usually compact but functional, offering basic dining and shopping; pros include proximity to the city and good domestic connections, while cons can be congestion at peak times and limited premium-lounge choices.
How much is the cheapest flight ticket from Guayaquil to Panama City?
The cheapest flight ticket from Guayaquil to Panama City according to data for the last 48 hours costs $182
When is the best time to buy air tickets on the route Guayaquil — Panama City?
Often the best time to buy tickets from Guayaquil to Panama City is 2 months before departure.
When is the cheapest time of year to fly from Guayaquil to Panama City?
Based on statistics over the past years, the lowest prices for flights from Guayaquil to Panama City can be found flying in these months: January, March, February.
How long does it take to fly from Guayaquil to Panama City?
The fastest flights from Guayaquil to Panama City start from 2 hours 10 minutes in the air.
Which airline can fly direct from Guayaquil to Panama City?
The following airlines operate direct flights on the route Guayaquil — Panama City: Copa Airlines
Tocumen International Airport (PTY) serves as Panama City’s main international gateway and regional hub, handling most long-haul and connecting flights with carriers such as Copa, American, and LATAM. It’s typically perceived as a mid-to-upper range airport with a wide choice of lounges, shops and transit connections. The airport lies about 24 km (roughly 30–45 minutes by road) from the historic Casco Viejo; taxis, ride-hailing services and airport shuttles are common, with fares that can vary from economical shared shuttles to higher-cost private transfers. Pros: extensive international connections and decent passenger facilities. Cons: can be busy at peak times and ground transfers may be impacted by city traffic.
We couldn't find any special offers for flights from Guayaquil to Panama City
